Devices and methods for the delivery of molecular sieve materials for the formation of blood clots
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61L-015/14
A61L-015/16
A61L-015/18
A61K-009/14
A61F-013/00
출원번호
US-0555876
(2009-09-09)
등록번호
US-8257731
(2012-09-04)
발명자
/ 주소
Horn, Jeffry
Huey, Raymond
출원인 / 주소
Z-Medica Corporation
대리인 / 주소
Knobbe Martens Olson & Bear, LLP
인용정보
피인용 횟수 :
17인용 특허 :
77
초록▼
An apparatus for promoting the clotting of blood and controlling bleeding comprises a receptacle for retaining molecular sieve material in particulate form therein. A pad for controlling bleeding comprises a mesh structure and a rigid or semi-rigid support attached to the mesh structure to facilitat
An apparatus for promoting the clotting of blood and controlling bleeding comprises a receptacle for retaining molecular sieve material in particulate form therein. A pad for controlling bleeding comprises a mesh structure and a rigid or semi-rigid support attached to the mesh structure to facilitate the application of pressure to the pad and the wound. A bandage applicable to a bleeding wound comprises a mesh structure and a flexible substrate attached to the mesh structure, the substrate being a cloth or plastic member that may be adhesively attached to cover a wound. In any embodiment, at least a portion of the receptacle or mesh structure is defined by a mesh having openings therein, and at least a portion of the particulate molecular sieve material is in direct contact with blood.
대표청구항▼
1. A device for promoting the clotting of blood comprising: a pouch that is closed on all sides; anda molecular sieve in particle form which is retained in the pouch;wherein the pouch is composed of a mesh comprising a plurality of openings;wherein the molecular sieve particles are: sufficiently lar
1. A device for promoting the clotting of blood comprising: a pouch that is closed on all sides; anda molecular sieve in particle form which is retained in the pouch;wherein the pouch is composed of a mesh comprising a plurality of openings;wherein the molecular sieve particles are: sufficiently large to be retained by the mesh; andsufficiently small so that at least a portion of the particles can protrude through at least a portion of the openings of the mesh to make direct contact with blood outside of the pouch. 2. The device of claim 1, wherein the molecular sieve comprises a zeolite. 3. The device of claim 1, wherein the mesh comprises at least one of polyester, cotton, wool, or silk. 4. The device of claim 1, wherein the particles have a diameter from about 2 mm to about 5 mm. 5. The device of claim 1, further comprising a pharmaceutically-active composition which is mixed with, associated with, or incorporated into the molecular sieve. 6. The device of claim 1, further comprising sterile packaging within which the pouch is stored until the pouch is used. 7. A method of promoting the clotting of blood comprising: applying a device of claim 1 to a bleeding area of a mammal in need thereof. 8. The method of claim 6, wherein the molecular sieve comprises an A-type zeolite. 9. The method of claim 7, wherein the mesh comprises at least one of polyester, cotton, wool, or silk. 10. The method of claim 7, wherein the molecular sieve particles are sufficiently large to reduce an exothermia produced by contact with blood. 11. The method of claim 7, wherein the molecular sieve has a moisture content which is sufficiently high to reduce an exothermia associated with contact between blood and the molecular sieve, and wherein the moisture content is sufficiently low for the molecular sieve to be effective to promote the clotting of blood. 12. The method of claim 6, further comprising an antimicrobial agent which is mixed with, associated with, or incorporated into the molecular sieve. 13. The device of claim 2, wherein the molecular sieve comprises an A-type zeolite. 14. The device of claim 1, further comprising an anti-inflammatory agent which is mixed with, associated with, or incorporated into the molecular sieve. 15. The device of claim 1, further comprising an analgesic which is mixed with, associated with, or incorporated into the molecular sieve. 16. The device of claim 1, further comprising an antibiotic which is mixed with, associated with, or incorporated into the molecular sieve. 17. The device of claim 1, further comprising silver ions or a compound containing silver ions. 18. The device of claim 1, further comprising magnesium sulfate, sodium metaphosphate, calcium chloride, dextrin, a polysaccharide, combinations of the foregoing materials, or hydrates of the foregoing materials. 19. The device of claim 1, wherein the mesh is woven.
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