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Self-buffering medical implants

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-002/06
출원번호 US-0715577 (2010-03-02)
등록번호 US-8267992 (2012-09-18)
발명자 / 주소
  • Atanasoska, Liliana
  • Shippy, III, James Lee
  • Holman, Tom
  • Arney, Michael S.
  • Schoenle, Victor
  • Genovese, Frank
  • Feng, James Q.
  • Flanagan, Aiden
  • Weber, Jan
출원인 / 주소
  • Boston Scientific Scimed, Inc.
대리인 / 주소
    Fish & Richardson P.C.
인용정보 피인용 횟수 : 16  인용 특허 : 570

초록

A medical implant includes a bioerodible portion that includes a bioerodible polymer and a bioerodible metal. The bioerodible polymer matrix degrades under physiological conditions to form acidic degradation products. The bioerodible metal degrades under physiological conditions to form basic degrad

대표청구항

1. A medical implant comprising a bioerodible portion comprising: a bioerodible polymer matrix that degrades under physiological conditions to form acidic degradation products; anda bioerodible metal within the bioerodible polymer matrix, wherein the bioerodible metal degrades under physiological co

이 특허에 인용된 특허 (570)

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  194. Hideki Etori JP; Toshihiro Koike JP; Yasunori Sugiyama JP, Front scattering film.
  195. Ehrenberg Scott G. (Fishkill NY) Serpico Joseph (Troy NY) Wnek Gary E. (Latham NY) Rider Jeffrey N. (Troy NY), Fuel cell incorporating novel ion-conducting membrane.
  196. Alkhimov Anatoly P. (ulitsa Vyazemskogo 2 ; kv. 72 Novosibirsk SUX) Papyrin Anatoly N. (ulitsa Vyazemskogo 2 ; kv. 72 Novosibirsk SUX) Kosarev Vladimir F. (Novosibirsk SUX) Nesterovich Nikolai I. (No, Gas-dynamic spraying method for applying a coating.
  197. Schulz Andreas,DEX ; Schmid Gunter,DEX ; Hornyak Gabor Louis ; Sawitowski Thomas,DEX, Gold-containing nanoporous aluminum oxide membranes a process for their production and their use.
  198. Kveen Graig L. ; Doran Burns P. ; Judnitch Robert T., Helical stent design.
  199. Kouyama, Yuka; Hasegawa, Shinya; Numazawa, Yoichi, High frequency sputtering device.
  200. Greenwald Richard B. (Somerset NJ) Pendri Annapurna (Matawan NJ), High molecular weight polymer-based prodrugs.
  201. Konya, Andres; Wallace, Sidney; Wright, Kenneth C., Hoop stent.
  202. Hong, James; Bhagat, Rahul; Hossainy, Syed; Prabhu, Santosh; Rao, K.T. Venkateswara; Shah, Ashok; Sridharan, Srinivasan, Hybrid intravascular stent.
  203. Fan You-Ling (East Brunswick NJ), Hydrophilic lubricious coatings.
  204. Brandau, Wolfgang; Fischer, Alfons; Sawitowski, Thomas; Schmid, Guenter, Implant with cavities containing therapeutic agents.
  205. Brandau, Wolfgang; Fischer, Alfons; Sawitowski, Thomas; Schmid, Günter, Implant with permeable element.
  206. Stoll, Hans-Peter, Implant with proliferation-inhibiting substance.
  207. Edward A. Schroeppel ; Mark W. Kroll, Implantable device and method for the electrical treatment of cancer.
  208. Jean-Luc Dubois-Rande FR; Trung Le Doan FR; Minh Chau Pham FR; Benoit Piro FR; Emmanuel Teiger FR; Jean Pierre Tenu FR, Implantable device covered with polymer capable of releasing biologically active substances.
  209. Van Tassel,Robert A.; Holmes, Jr.,David R.; Schwartz,Robert S., Implantable device for promoting repair of a body lumen.
  210. Rehberg Christoph,DEX ; Kraus Werner,DEX,DEX, Implantable device having an internal electrode for stimulating growth of tissue.
  211. Hossainy, Syed F. A.; Ghio, Jacqueline; Chen, Li, Implantable device having substances impregnated therein and a method of impregnating the same.
  212. Uhland,Scott A., Implantable drug delivery device.
  213. Wu, Steven Z.; Sanders-Millare, Deborra; Harish, Sameer; Santos, Ryan J.; Chen, Li, Implantable drug delivery prosthesis.
  214. Jhabvala Murzban D. (Seabrook MD), Implantable electrical device.
  215. Wu Steven Z. ; Harish Sameer ; Sanders-Millare Deborra ; Guruwaiya Judy A., Implantable medical device having protruding surface structures for drug delivery and cover attachment.
  216. Shanley,John F.; Parker,Theodore L., Implantable medical device with drug filled holes.
  217. Miller, Kathleen M.; Sydney, Gregory T.; Geitz, Kurt; Dayton, Peter L.; Sahatjian, Ronald A., Implantable or insertable medical device resistant to microbial growth and biofilm formation.
  218. Vachon David J. ; Moaddeb Shahram, Implantable stimulation lead having an advanceable therapeutic drug delivery system.
  219. Soykan Orhan ; Donovan Maura G., Implantable system with drug-eluting cells for on-demand local drug delivery.
  220. Bolz Armin,DEX ; Popp Thomas,DEX, Implantable, bioresorbable vessel wall support, in particular coronary stent.
  221. Ellingsen, Jan Eirik; Videm, Ketil; Opsahl, Lars; Ronold, Hans Jacob, Implants with modified surfaces for increased biocompatibility, and method for production thereof.
  222. Andersen Erik (Roskilde DKX), Impregnated stent.
  223. Andersen Erik (Roskilde DKX), In situ apparatus for generating an electrical current in a biological environment.
  224. Dang, Kenny L.; Matin, Nazanine; Ho, Henjen, Increased drug-loading and reduced stress drug delivery device.
  225. Altman Peter A. (San Francisco CA) Bush M. Elizabeth (Fremont CA) Carson Dean F. (Mountain View CA), Intracardiac lead having a compliant fixation device.
  226. Altman Peter A. ; Bush M. Elizabeth ; Carson Dean F., Intracardiac lead having a compliant fixation device.
  227. Wolff Rodney G. (Minnetonka Beach MN) Hull Vincent W. (Ham Lake MN), Intralumenal drug eluting prosthesis.
  228. DiMatteo, Kristian; Ravenscroft, Adrian, Intraluminal lining.
  229. DeSimone, Joseph M.; Williams, Michael S., Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same.
  230. Schwartz Robert S., Intraluminal stent.
  231. Tseng, David; Golds, Ellen; Parsons, Bruce, Intraluminal stent.
  232. Motasim Sirhan ; John Yan, Intravascular delivery of mycophenolic acid.
  233. Drasler William J. ; Thielen Joseph M., Intravascular folded tubular endoprosthesis.
  234. Schwartz Robert S. (Rochester MN) Tuch Ronald G. (Plymouth MN) Wolff Rodney G. (Minnetonka MN), Intravascular medical device.
  235. Schwartz Robert S. (Rochester MN) Bresnahan John (Rochester MN) Bergman Rebecca M. (North Oaks MN) Coury Arthur J. (St. Paul MN) Lindell Elaine (Blaine MN) Hull Vincent W. (Fridley MN) Dror Michael (, Intravascular radially expandable stent.
  236. Wiktor Dominik M. (Cranford NJ), Intravascular radially expandable stent and method of implant.
  237. Jang G. David, Intravascular stent.
  238. Sigwart Ulrich (Morges CHX), Intravascular stent.
  239. Yip, Philip S.; Prabhu, Santosh, Intravascular stent.
  240. Yip, Philip S.; Tsang, P. H. Wilson; Ho, Henjen; Limon, Timothy A.; Atladottir, Svava Maria, Intravascular stent.
  241. Berg Eric P. (Plymouth MN) Tuch Ronald J. (Plymouth MN) Dror Michael (Edina MN) Wolff Rodney G. (Minnetonka Beach MN), Intravascular stent and method.
  242. Tuch Ronald J. (Plymouth MN), Intravascular stent and method.
  243. Palmaz Julio C. ; Sprague Eugene A., Intravascular stent and method for manufacturing an intravascular stent.
  244. Jang, G. David, Intravascular stent with increasing coating retaining capacity.
  245. Tuch Ronald J., Intravasoular stent and method.
  246. White,Jennifer K., Involuted endovascular valve and method of construction.
  247. Atanasoska Ljiljana ; Maurer Donald ; Stripsky Marc, Iontophoresis electrode.
  248. Milder Fredric L. (Brookline MA), Iontophoretic structure for medical devices.
  249. Van Steenkiste Thomas H. ; Smith John R. ; Teets Richard E. ; Moleski Jerome J. ; Gorkiewicz Daniel W., Kinetic spray coating apparatus.
  250. Van Steenkiste Thomas H. ; Smith John R. ; Teets Richard E. ; Moleski Jerome J. ; Gorkiewicz Daniel W., Kinetic spray coating method and apparatus.
  251. Whitesides, George M.; Kumar, Amit, Kit For Microcontact Printing.
  252. Gustafson Gary E., Laser cutting tool for cutting elongated hollow workpieces.
  253. Kenneth M. Merdan ; Vitaliy N. Shapovalov, Laser deposition of elements onto medical devices.
  254. Flanagan, Aiden, Laser stent cutting.
  255. Holloway, Ken A.; Christoforou, Christofer T., Layered stent-graft and methods of making the same.
  256. Pathak,Chandrashekhar, Liquid and low melting coatings for stents.
  257. Nonami Tohru (Ichikawa JPX) Yasui Nobuo (Narita JPX), Living hard tissue replacement, its preparation.
  258. Hastings Roger N. ; Wang Lixiao ; Yang Dachuan ; Ungs Mark T. ; Urick Michael J., Local application of oxidizing agents to prevent restenosis.
  259. Llanos,Gerard H.; Lentz,David Christian, Local drug delivery devices and methods for maintaining the drug coatings thereon.
  260. Lennox Charles D., Localized delivery of drug agents.
  261. Lennox, Charles D., Localized delivery of drug agents.
  262. Bucay-Couto, Weenna; Li, Jamie (Jianmin), Long-term indwelling medical devices containing slow-releasing antimicrobial agents and having a surfactant surface.
  263. Brown, Brian J.; Davis, Michael; Friesen, David; Ley, Timothy J.; Skubitz, Sean P., Longitudinally flexible expandable stent.
  264. Brown,Brian J.; Davis,Michael L., Longitudinally flexible expandable stent.
  265. Sage, Jr., Burton H.; DeNuzzio, John R.; Bock, C. Randolph; Haynes, John L.; Reddy, Vilambi, Low cost electrodes for an iontophoretic device.
  266. Burrell, Robert Edward; Yin, Hua Qing; Naylor, Antony George; Moxham, Peter Howard; Cholowski, Walter Carlton Theodore; Bowlby, Leonard Salvin; Field, David James, Lubricious coatings for substrates.
  267. Elton Richard K. (Glens Falls NY), Lubricious hydrogel coatings.
  268. Igaki, Keiji; Tamai, Hideo, Luminal stent, holding structure therefor and device for attaching luminal stent.
  269. Deininger William D. (Pasadena CA) Gabriel Stephen B. (La Crescenta CA), Luminal surface fabrication for cardiovascular prostheses.
  270. Melzer, Andreas; Busch, Martin, MR imaging method and medical device for use in method.
  271. Pacetti, Stephen Dirk, MRI compatible stent.
  272. Zimmermann, Michael, Magnesium ammonium phosphate cement composition.
  273. Wang, Xingwu; Greenwald, Howard J.; Helfer, Jeffrey L.; Gray, Robert W.; Weiner, Michael L., Magnetic resonance imaging coated assembly.
  274. Wang, Xingwu; Helfer, Jeffrey L.; MacDonald, Stuart G., Magnetically shielded assembly.
  275. Wang, Xingwu; Helfer, Jeffrey L.; MacDonald, Stuart G., Magnetically shielded assembly.
  276. Wang, Xingwu, Magnetically shielded conductor.
  277. Berg Eric P. ; Dinh Thomas Q., Medical device for delivering a therapeutic substance and method therefor.
  278. Berg, Eric P.; Dinh, Thomas Q., Medical device for delivering a therapeutic substance and method therefor.
  279. Parsonage, Edward, Medical device including cylindrical micelles.
  280. Zabetakis Paul M. (Stamford CT) Cotell Catherine M. (Alexandria VA) Chrisey Douglas B. (Bowie MD), Medical device with infection preventing feature.
  281. Ding, Ni, Medical device with porous surface for controlled drug release and method of making the same.
  282. Ni Ding ; W. Scott Andrus, Medical device with sponge coating for controlled drug release.
  283. Gregorich, Daniel J.; Stinson, Jonathan S., Medical devices and methods of making the same.
  284. Gregorich,Daniel J.; Stinson,Jonathan S., Medical devices and methods of making the same.
  285. Palmaz,Julio C., Medical devices having MEMs functionality and methods of making same.
  286. Lye,Whye Kei; Looi,Kareen; Reed,Michael L., Medical devices having porous layers and methods for making same.
  287. Koziak, Joseph; Naicker, Selvaraj; Yatscoff, Randall W.; Foster, Robert T., Medical devices incorporating deuterated rapamycin for controlled delivery thereof.
  288. Stewart, Mark T.; Iverson, Vernon B.; Keeney, Kenneth W.; Taylor, Catherine E., Medical electrical lead having controlled texture surface and method of making same.
  289. Yan, John Y., Medicated porous metal prosthesis.
  290. Chen, Yung-Ming, Metal prosthesis coated with expandable ePTFE.
  291. Yoon, Jung-Han, Metal stent for insertion in coronary artery.
  292. Scheuermann,Torsten; Stehling,Lutz, Metal stent with surface layer of noble metal oxide and method of fabrication.
  293. Birdsall,Matthew J.; Klein,Richard L.; Maier,Nathan, Metallic composite coating for delivery of therapeutic agents from the surface of implantable devices.
  294. Schofield Andrew,CHX, Method and apparatus for asynchronously calling and implementing objects.
  295. Yoe, Brandon J., Method and apparatus for coating an implantable device.
  296. Sceusa, Nicholas A., Method and apparatus for delivery of medication.
  297. Richard J. Saunders, Method and apparatus for direct laser cutting of metal stents.
  298. Saunders Richard J., Method and apparatus for direct laser cutting of metal stents.
  299. Saunders Richard J., Method and apparatus for direct laser cutting of metal stents.
  300. Kroll Kai ; Kroll Mark W., Method and apparatus for electrically forcing cardiac output in an arrhythmia patient.
  301. Dufresne Michael J. ; Lundblad LeRoy J., Method and apparatus for etching-manufacture of cylindrical elements.
  302. Feiring Andrew J. (4454 N. Murray Ave. Milwaukee WI 53211), Method and apparatus for inducing the permeation of medication into internal tissue.
  303. Kumar B. Ajit ; Khanwilkar Pratap ; Olsen Don B., Method and apparatus for providing a conductive, amorphous non-stick coating.
  304. Feldman,Marc D.; Bailey,Stephen R.; Agrawal,C. Mauli; Athanasiou,Kyriacos A., Method and apparatus for stent deployment with enhanced delivery of bioactive agents.
  305. Davis William M. (Tucson AZ) Chvapil Milos (Tucson AZ), Method and apparatus for treatment of fibrotic lesions.
  306. Joel R. Studin, Method and composition for the treatment of scars.
  307. Kaplan Aaron V. (3477 Thomas Dr. Palo Alto CA 94303), Method and device for treating and enlarging body lumens.
  308. Clapper David L., Method and implantable article for promoting endothelialization.
  309. Reiss, Paul, Method and system for creating a textured surface on an implantable medical device.
  310. Kirkpatrick, Allen R.; Becker, Robert K.; Freytsis, Avrum, Method and system for improving the effectiveness of medical stents by the application of gas cluster ion beam technology.
  311. Reiss, Paul, Method for creating a textured surface on an implantable medical device.
  312. Leone James E. ; Hennemann ; III Willard W. ; Rowland Stephen M., Method for delivering a liquid solution to the interior wall surface of a vessel.
  313. Tuch Ronald J., Method for delivering a therapeutic substance to a body lumen.
  314. Shirkanzadeh Morteza (Kingston CAX), Method for depositing bioactive coatings on conductive substrates.
  315. Hossainy, Syed F. A.; Chen, Li, Method for etching a micropatterned microdepot prosthesis.
  316. Buscemi Paul J. ; Stejskal Elizabeth A. ; Palme ; II Donald F. ; Wang Lixiao, Method for making a biodegradable stent.
  317. Charles V. Tomonto, Method for making a multi-laminate stent having superelastic articulated sections.
  318. Clubb Thomas L. ; Donadio ; III James V. ; Dustrude Mark O. ; Shapland ; II J. Edward, Method for making a stent.
  319. Donadio ; III James V., Method for making a tubular stent for use in medical applications.
  320. Flanagan, Aiden, Method for making and measuring a coating on the surface of a medical device using an ultraviolet laser.
  321. Weber, Jan, Method for manufacturing a medical device having a coated portion by laser ablation.
  322. Lorenz Hans P. (Schwarzenbruk DEX) Straehler Bernd (Berlin DEX) Lindegren Ulf (Enskede SEX), Method for manufacturing a medical electrode.
  323. Ding Ni, Method for manufacturing an expandable stent.
  324. Bales, Thomas O.; Jahrmarkt, Scott L., Method for microporous surface modification of implantable metallic medical articles.
  325. Egitto Frank Daniel (Binghamton NY) Matienzo Luis Jesus (Endicott NY) Morrison ; Jr. Bruce Otho (Vestal NY), Method for producing a diffusion barrier and polymeric article having a diffusion barrier.
  326. George A. Shukov, Method for production of an expandable stent.
  327. Whitney Douglass G. (11200 Bowen Rd. Roswell GA 30075), Method for promoting blood vessel healing.
  328. Weber, Jan; Kocur, Gordon John, Method for spray-coating a medical device having a tubular wall such as a stent.
  329. Hansen, Henrik, Method for spray-coating medical devices.
  330. Schmitz Klaus-Peter,DEX ; Behrend Detlef,DEX, Method for the manufacture of intraluminal stents of bioresorbable polymeric material.
  331. Schaldach, Jr., Max; Schmitz, Klaus-Peter; Gobrecht, Jens; Rzany, Alexander; Behrend, Detlef, Method of applying a marker element to an implant and an implant provided with a marker element.
  332. Weber,Jan, Method of coating a medical device using an electrowetting process.
  333. Banas Conrad M. (Manchester CT), Method of cutting with laser radiation and liquid coolant.
  334. Alt Eckhard,DEX, Method of fabricating a biocompatible stent.
  335. Johnson Michael W., Method of forming a stent.
  336. Guruwaiya Judy A. ; Millare Deborra Sanders ; Wu Steven Z-H, Method of layering a three-coated stent using pharmacological and polymeric agents.
  337. Dinh Thomas Q. (Minnetonka MN) Tuch Ronald J. (Plymouth MN) Schwartz Robert S. (Rochester MN), Method of making a drug eluting stent.
  338. Thompson Paul J., Method of making a stent-graft covered with expanded polytetrafluoroethylene.
  339. Campbell Patrick K. (Georgetown MA), Method of making metal reinforced polymer stent.
  340. Susawa Takashi (13-2-309 ; Okubo-cho Tanakakami ; Sakyo-ku ; Kyoto-shi ; Kyoto-fu JPX) Ioaki Keiji (1-21 ; Wakakusa 2-chome Kusatsu-shi ; Shiga-ken JPX) Tamai Hideo (50-19 ; Miyake-cho Moriyama-shi ;, Method of manufacturing a device to dilate ducts in vivo.
  341. Yan John Y., Method of manufacturing a medicated porous metal prosthesis.
  342. Padilla, Orlando; Esser, Keith; Zeltinger, Joan, Method of manufacturing a prosthesis.
  343. Lee, Dosuk D.; Rey, Christian; Aiolova, Maria; Tofighi, Aliassghar, Method of preparing a poorly crystalline calcium phosphate and methods of its use.
  344. Chekanov Valeri S., Method of prevention and treatment of atherosclerosis and article of manufacture therefor.
  345. McGill Robert Andrew ; Chrisey Douglas Brian, Method of producing a film coating by matrix assisted pulsed laser deposition.
  346. Loeb Gerald E.,CAX ; Richmond Frances J. R.,CAX, Method of reducing the incidence of medical complications using implantable microstimulators.
  347. Talton,James D., Methods for coating particles and particles produced thereby.
  348. Sheppard, Jr., Norman F.; Feakes, Christina M., Methods for conformal coating and sealing microchip reservoir devices.
  349. Ding, Ni; Sanders Millare, Deborra; Hossainy, Syed F. A., Methods for polymeric coatings stents.
  350. Talton,James D.; Hochhaus,Guenther; Singh,Rajiv K.; Fitz Gerald,James M., Methods for preparing coated drug particles and pharmaceutical formulations thereof.
  351. Elkins,Christopher J.; Dake,Michael D.; Waugh,Jacob M., Methods for the inhibition of neointima formation.
  352. Zadno-Azizi Gholam-Reza ; Luehrs Kirsten F. ; Gittings Darin C. ; Turovskiy Roman ; Cox Brian J. ; Shiu Brian ; Hayes Michael B. ; Coombs Craig J., Methods for the manufacture of radially expansible stents.
  353. Blinn,Stephen M.; Zide,Barry M.; DiFilippo,Vincent; Kirkpatrick,Sean, Methods of adhering drugs to the surface of medical devices through ion beam surface modification.
  354. Jeffrey M. Garibaldi ; Bevil J. Hogg ; Roger N. Hastings ; Brooke Ren, Methods of and compositions for treating vascular defects.
  355. Harish, Sameer; Wu, Steven Z.; Scheinpflug, Kurt W.; Yoe, Brandon, Methods of coating an implantable device having depots formed in a surface thereof.
  356. Harish, Sameer; Wu, Steven; Sanders Millare, Deborra; Guruwaiya, Judy; Pacetti, Stephen; Hossainy, Syed Faiyaz Ahmed, Methods of forming a coating for a prosthesis.
  357. Stinson, Jonathan S., Methods of making medical devices.
  358. Kramer, Pamela A.; Carlson, James M., Methods of manufacture of fully consolidated or porous medical devices.
  359. Lynn Cook Winterton ; Juergen Vogt CH; John Martin Lally ; Friedrich Stockinger CH, Methods of modifying surface characteristics.
  360. Jacobsen Stephen C. ; Lippert John, Micro-machined stent for vessels, body ducts and the like.
  361. Rourke Jonathan M. ; Yang Yi, Micro-porous mesh stent with hybrid structure.
  362. Takada Shigeyuki,JPX ; Kurokawa Tomofumi,JPX ; Iwasa Susumu,JPX, Microcapsule containing amorphous water-soluble 2-piperazinone-1-acetic acid compound.
  363. Santini ; Jr. John T. ; Cima Michael J. ; Langer Robert S., Microchip drug delivery devices.
  364. Broderick Patricia A., Microelectrodes and their use in an electrochemical arrangement with telemetric application.
  365. John T. Santini, Jr. ; Charles E. Hutchinson ; Scott A. Uhland ; Michael J. Cima ; Robert S. Langer ; Dennis Ausiello, Microfabricated devices for the delivery of molecules into a carrier fluid.
  366. Naimark, Wendy; Palasis, Maria, Microparticle protection of therapeutic agents.
  367. Zaffaroni Alejandro (Atherton CA), Microporous drug delivery device.
  368. McDonald Edward A. ; Henson Michael ; Young Joe W., Microporous tubular prosthesis.
  369. Tu Roger (Lake Forrest CA) Chen David (Irvine CA) Mathewson Wilfred F. (Dana Point CA), Microporous vascular graft.
  370. Dayton Michael P. (14802 Hadleigh Way Tampa FL 33624), Minimally invasive bioactivated endoprosthesis for vessel repair.
  371. Dayton Michael P. (14802 Hadleigh Way Tampa FL 33624), Minimally invasive bioactivated endoprosthesis for vessel repair.
  372. Wright Carol ; Llanos Gerard H. ; Rakos Ronald ; King Kristen, Modified stent useful for delivery of drugs along stent strut.
  373. Rubner Michael F. (Westford MA) Cheung Josephine Ho-Wah (Columbia MD), Molecular self-assembly of electrically conductive polymers.
  374. Chuanting You, Monolayer modification to gold coated stents to reduce adsorption of protein.
  375. Palasis,Maria, Multi-balloon catheter with hydrogel coating.
  376. Tomonto Charles V., Multi-laminate stent having superelastic articulated sections.
  377. Henderson, Jamie S., Multi-lumen vascular grafts having improved self-sealing properties.
  378. Camrud Allen R. ; Schwartz Robert S. ; Holmes ; Jr. David R. ; Argo Timothy D. ; Berry David, Multi-section stent.
  379. Gopalraja,Praburam; Fu,Jianming; Chen,Fusen; Dixit,Girish; Xu,Zheng; Wang,Wei; Sinha,Ashok K., Multi-step magnetron sputtering process.
  380. Omprakash S. Kolluri, Multilayer and multifunction vascular graft.
  381. Eckert John K. ; Farina Jeffrey M. ; Gadda Joseph P. ; Kelly Jeffrey C. ; Thomas John G., Multilayer composite tubular structure and method of making.
  382. Hamlin Robert N. (Stillwater MN), Multilayer extrusion of angioplasty balloons.
  383. Eury Robert P. (Cupertino CA), Multilayered biodegradable stent and method of manufacture.
  384. Legome Mark J. ; Conrad Georgia L. ; Laurenson Michael R., Mushroom and loop material closure system for high shear strength and low peel strength applications.
  385. Namavar, Fereydoon, Nano-crystalline, homo-metallic, protective coatings.
  386. Namavar,Fereydoon, Nano-crystalline, homo-metallic, protective coatings.
  387. Lan Tie ; Westphal Erin K., Nanocomposites formed by onium ion-intercalated clay and rigid anhydride-cured epoxy resins.
  388. Maxfield MacRae (Plainfield NJ) Christiani Brian R. (Maplewood NJ) Murthy Sanjeeva N. (Neshanic Station NJ) Tuller Harold (Long Valley NJ), Nanocomposites of gamma phase polymers containing inorganic particulate material.
  389. Ying Jackie Y. ; Ahn Edward S. ; Nakahira Atsushi,JPX, Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production.
  390. Wang, Xingwu; Greenwald, Howard J.; Miller, Ronald E., Nanomagnetic composition.
  391. McNamara Thomas O. (919 Levering #505 Los Angeles CA 90024) Mednik Gregory (1530 N. Pointettia Place #221 Los Angeles CA 90046), Nitinol stent for hollow body conduits.
  392. Mather,Patrick T.; Kim,Byoung Suhk; Ge,Qing; Liu,Changdeng, Nonionic telechelic polymers incorporating polyhedral oligosilsesquioxane (POSS) and uses thereof.
  393. Zaffaroni Alejandro (Atherton CA), Novel drug delivery device.
  394. Kubota Takeshi (Tokyo-to JPX), Optical card.
  395. Barry, James J.; Kamath, Kalpana R., Optimized dosing for drug coated stents.
  396. Golds Ellen ; Lentz David J. ; Henderson Jamie ; Dormier Edward J. ; Zdrahala Richard J., PTFE vascular prosthesis and method of manufacture.
  397. Yanjing Liu ; Guy A. Schick, Patterned molecular self-assembly.
  398. Porat Yariv,ILX ; Tsaliah Yoseph,ILX ; Doron Eyal,ILX, Piezoelectric transducer.
  399. Zamora, Paul O.; Osaki, Shigemasa; Chen, Meng, Plasma-deposited coatings, devices and methods.
  400. Castro, Daniel; Pacetti, Stephen D., Poly(butylmethacrylate) and rapamycin coated stent.
  401. Swetlin,Brian J.; Mazich,Kenneth A., Polyester compositions, methods of manufacturing said compositions, and articles made therefrom.
  402. David Tseng ; William Donahue ; Bruce A. Parsons, Polymer coated stent.
  403. Rypacek,Frantisek; Lapcikova,Monika; Machova,Ludka, Polymer coating for medical devices.
  404. Van Antwerp, William P., Polymer compositions containing bioactive agents and methods for their use.
  405. Tartaglia Joseph M. (Redwood City CA) Loeffler Joseph P. (Mountain View CA) Turnlund Todd H. (Mountain View CA), Polymer film for wrapping a stent structure.
  406. Kalpana R. Kamath ; James J. Barry ; Sepideh H. Nott, Polymeric coatings for controlled delivery of active agents.
  407. Pinnavaia Thomas J. (East Lansing MI) Kwon Taehyun (Ithaca NY) Dimotakis Emmanuel D. (East Lansing MI) Amarasekera Jayantha (East Lansing MI), Polyoxometalate intercalated layered double hydroxides.
  408. Yan John Y., Porous medicated stent.
  409. Hossainy Syed F. A. ; Chen Li, Porous prosthesis and a method of depositing substances into the pores.
  410. Date, Kenji; Nakai, Masumi, Porous sintered metal and filter thereof, and method for producing porous sintered metal.
  411. Johnson Michael W., Porous stent drug delivery system.
  412. Mano Hiroshi (Osaka JPX), Porous structure of polytetrafluoroethylene and process for production thereof.
  413. Hoshino Kouji,JPX ; Mayuzumi Yoshitaka,JPX ; Kohno Tohru,JPX ; Komada Norikazu,JPX, Porus metallic material having high specific surface area, method of producing the same, porus metallic plate material and electrode for alkaline secondary battery.
  414. Jeutter Dean C. (Grafton WI), Position sensitive power transfer antenna.
  415. LaForge David H. (Kensington CA) Portner Peer M. (Berkeley CA), Power supply for body implant and method for operation.
  416. LaForge David H. (Kensington CA) Lee James (Benicia CA), Power supply for body implant and method of use.
  417. Alt Eckhard,DEX, Premounted stent delivery system for small vessels.
  418. Zhang,Xinghang; Misra,Amit; Nastasi,Michael A.; Hoagland,Richard G., Preparation of high-strength nanometer scale twinned coating and foil.
  419. Scheuermann,Torsten; Alt,Eckhard, Primarily niobium stent.
  420. Hossainy Syed F. A. ; Roller Mark B. ; Llanos Gerard H. ; Kopia Gregory A., Process for coating stents.
  421. Hines, Richard A., Process for forming a porous drug delivery layer.
  422. Flanagan, Aiden, Process for laser joining dissimilar metals and endoluminal stent with radiopaque marker produced thereby.
  423. Thompson Paul J., Process for manufacturing braided composite prosthesis.
  424. Heller Adam (Austin TX) Argitis Panagiotis (Piraeus TX GRX) Carls Joseph C. (Austin TX), Process for metal deposition for microelectronic interconnections.
  425. Kaese, Volker; Pinkvos, Arne; Haferkamp, Heinz; Niemeyer, Matthias; Bach, Friedrich-Wilhelm, Process for producing bioresorbable implants.
  426. Sterzel Hans-Josef,DEX ; Hesse Michael,DEX ; Kleinke Andreas,DEX, Process for producing open-celled, inorganic sintered foam products.
  427. Panagiotou Thomai ; Levendis Yiannis, Process for producing polymer coatings with various porosities and surface areas.
  428. Sagiv, Jacob, Process for the production of built-up films by the stepwise adsorption of individual monolayers.
  429. Callahan James L. (Norwich NY) Desmond Michael J. (Cleveland Heights OH) Pepera Marc A. (Northfield Center OH), Process for the reductive deposition of polyoxometallates.
  430. Sridharan, Srinivasan; Simhambhatla, Murthy V., Process of making polymer articles.
  431. Epstein, Samuel J.; Naimark, Wendy, Processes for producing polymer coatings for release of therapeutic agent.
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