IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
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출원번호 |
US-0805311
(2007-05-23)
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등록번호 |
US-8271080
(2012-09-18)
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발명자
/ 주소 |
- Thompson, Julie A.
- Dalal, Yousufali H.
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 |
피인용 횟수 :
0 인용 특허 :
54 |
초록
▼
Assessing decongestive therapy delivered to a heart failure patient involves use of an implantable sensor configured to sense a physiologic parameter indicative of the patient's diuresis status and a processor coupled to the implantable sensor. The sensor may comprise a thoracic fluid sensor, a hear
Assessing decongestive therapy delivered to a heart failure patient involves use of an implantable sensor configured to sense a physiologic parameter indicative of the patient's diuresis status and a processor coupled to the implantable sensor. The sensor may comprise a thoracic fluid sensor, a heart sounds sensor, a cardiac chamber or arterial pressure sensor, a respiration sensor, or a blood chemistry sensor, for example. The processor is configured to determine if a target level of patient diuresis has been achieved based on a relationship between the sensed physiologic parameter and a threshold developed for the patient, and to produce an output in response to determining that the target level of patient diuresis has been achieved. The processor may be disposed in an implantable housing, in a patient-external housing, or in a network server system.
대표청구항
▼
1. A system for assessing decongestive therapy delivered to a heart failure patient, comprising: an implantable sensor configured to sense a physiologic parameter indicative of the patient's diuresis status responsive to delivery of a decongestive therapy; anda processor coupled to the implantable s
1. A system for assessing decongestive therapy delivered to a heart failure patient, comprising: an implantable sensor configured to sense a physiologic parameter indicative of the patient's diuresis status responsive to delivery of a decongestive therapy; anda processor coupled to the implantable sensor, the processor configured to determine if the patient is being subject to over-therapeuting when a target level of patient diuresis has been achieved based on a relationship between the sensed physiologic parameter and a threshold developed for the patient, produce a first output in response to determining that the target level of patient diuresis has been achieved, and produce a second output in response to determining that the patient is being subject to over-therapeuting, wherein the second output comprises an alert indicating detection of over-diuresis of the patient, wherein the relationship is based on a rate of change of the sensed physiologic parameter relative to the threshold. 2. The system of claim 1, wherein the system further comprises a sensor configured to sense a signal indicative of cardiac congestion, and wherein the processor is further configured to detect a congestive event based on the signal and control sensing of the physiologic parameter by the implantable sensor responsive to detection of the congestive event. 3. The system of claim 1, wherein the processor is configured to adjust the decongestive therapy based on the determination of over-therapeuting. 4. The system of claim 1, wherein the processor is configured to detect non-responsiveness of the patient to the decongestive therapy and generate an alert in response to detecting the non-responsiveness. 5. The system of claim 1, wherein the processor is configured to adjust sensing of the physiologic parameter by the implantable sensor based on a type of medication administered to the patient for decongestive therapy. 6. The system of claim 1, wherein the processor is configured to adjust sensing of the physiologic parameter by the implantable sensor based on the manner of delivering the decongestive therapy. 7. The system of claim 1, wherein the processor is configured to determine the patient's sensitivity of response to the decongestive therapy. 8. The system of claim 1, wherein the threshold is associated with a prior successful therapy delivered to the patient. 9. The system of claim 1 wherein the relationship between the sensed physiologic parameter and the threshold comprises at least one of: a rate of change of increase or decrease of the sensed physiologic parameter relative to the threshold; anda rate of change of increase or decrease of the sensed physiologic parameter relative to a safe level of patient diuresis established as the threshold. 10. A system for assessing decongestive therapy delivered to a heart failure patient, comprising: an implantable sensor configured to sense a physiologic parameter indicative of the patient's diuresis status responsive to delivery of a decongestive therapy; anda processor coupled to the implantable sensor, the processor configured to determine if the patient is being subject to over-therapeuting when a target level of patient diuresis has been achieved based on a relationship between the sensed physiologic parameter and a threshold developed for the patient, produce a first output in response to determining that the target level of patient diuresis has been achieved, and produce a second output in response to determining that the patient is being subject to over-therapeuting, wherein the second output comprises an alert indicating detection of over-diuresis of the patient, wherein the relationship is based on a rate of change of the sensed physiologic parameter relative to the threshold, and wherein the therapy comprises at least one of a drug therapy, a neurostimulation therapy, and a cardiac electrical stimulation therapy. 11. A system for assessing decongestive therapy delivered to a heart failure patient, comprising: an implantable sensor configured to sense a physiologic parameter indicative of the patient's diuresis status responsive to delivery of a decongestive therapy; anda processor coupled to the implantable sensor, the processor configured to determine if the patient is being subject to over-therapeuting when a target level of patient diuresis has been achieved based on a relationship between the sensed physiologic parameter and a threshold developed for the patient, produce a first output in response to determining that the target level of patient diuresis has been achieved, and produce a second output in response to determining that the patient is being subject to over-therapeuting, wherein the second output comprises an alert indicating detection of over-diuresis of the patient, wherein the relationship is based on a rate of change of the sensed physiologic parameter relative to the threshold, and wherein the threshold is a threshold developed specifically for the patient.
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