Certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) are used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. Th
Certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) are used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. The pumps may be configured specifically to impart low shear forces and low turbulence on the fluid as the fluid is pumped from an inlet to an outlet. Such pumps may be particularly useful in pumping fluids that may be damaged by such shear forces (e.g., blood, and particularly heated blood, which is prone to hemolysis) or turbulence (e.g., surfactants or other fluids that may foam or otherwise be damaged or become unstable in the presence of turbulence).
대표청구항▼
1. A pumping system comprising: a reciprocating positive-displacement pump comprising: a hemispherical rigid chamber wall;a rigid limit structure;a flexible membrane attached to the rigid chamber wall and interposed between the rigid chamber wall and the rigid limit structure, such that the flexible
1. A pumping system comprising: a reciprocating positive-displacement pump comprising: a hemispherical rigid chamber wall;a rigid limit structure;a flexible membrane attached to the rigid chamber wall and interposed between the rigid chamber wall and the rigid limit structure, such that the flexible membrane and rigid chamber wall together define a pumping chamber and the flexible membrane and the rigid limit structure together define an actuation chamber, and wherein the rigid limit structure is constructed and positioned to limit movement of the membrane and limit the maximum volume of the pumping chamber;an inlet for directing flow through the rigid chamber wall into the pumping chamber;an outlet for directing flow through the rigid chamber wall out of the pumping chamber; andan actuation system that alternately provides either a positive or a negative pressure to the actuation chamber; wherein the actuation system includes: a reservoir containing a control fluid at either a positive or a negative pressure, anda valving mechanism for controlling a flow of control fluid between the actuation chamber and the reservoir;an actuation-chamber pressure transducer for measuring a pressure of the actuation chamber; anda controller that receives pressure information from the actuation-chamber pressure transducer and controls the valving mechanism, wherein the controller determines a first measure of an integral of pressure information from the actuation-chamber pressure transducer as a function of time during a stroke, and uses said first measure in determining the presence of an aberrant flow condition. 2. The pumping system according to claim 1, further including: a reservoir pressure transducer for measuring a pressure of gas in the reservoir,wherein the controller receives pressure information from the reservoir pressure transducer. 3. The pumping system according to claim 2, wherein the controller compares the pressure information from the actuation-chamber and reservoir pressure transducers to determine whether either of the pressure transducers are malfunctioning. 4. The pumping system according to claim 1, wherein the inlet is configured and positioned for directing flow through the rigid chamber wall into the pumping chamber in a direction that is substantially tangential to the rigid chamber wall, and the outlet is configured and positioned for directing flow through the rigid chamber wall out of the pumping chamber in at least one of (a) a direction that is substantially tangential to the rigid chamber wall and (b) a direction that provides low-shear flow out of the pumping chamber. 5. The pumping system according to claim 1, further comprising a pathway adjacent the rigid chamber wall configured to maintain fluid communication between the inlet and the outlet even when the flexible membrane is fully extended towards the hemispherical rigid chamber wall such that the pumping chamber is at a minimum volume. 6. The pumping system according to claim 1, wherein the controller determines a second measure of an integral of pressure information from the actuation-chamber pressure transducer as a function of time during a series of pump strokes, the second measure following the first measure, compares the integral based on the second measure to the integral based on the first measure, and if the integral based on the first measure deviates from the integral based on the second measure by a predetermined amount, uses said comparison in determining the presence of an aberrant flow condition. 7. The pumping system according to claim 6, wherein the controller compares the first measure of the integral of pressure information of said pump stroke to a second measure of an integral of pressure information during three or fewer pump strokes preceding it, and if the integral based on the first measure of said pump stroke deviates from the integral based on the second measure of the preceding three or fewer pump strokes by a predetermined amount, uses said comparison in determining the presence of an aberrant flow condition. 8. The pumping system according to claim 6, wherein the controller monitors the actuation chamber pressure transducer to determine whether the end of a pump stroke has been reached by measuring a decrease in pressure fluctuations in the actuation chamber, and if so, generates a signal indicating that the aberrant flow condition is related to a downstream flow restriction, occlusion or a pneumatic actuation problem.
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