IPC분류정보
국가/구분 |
United States(US) Patent
등록
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국제특허분류(IPC7판) |
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출원번호 |
US-0717886
(2010-03-04)
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등록번호 |
US-8292952
(2012-10-23)
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발명자
/ 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 |
피인용 횟수 :
0 인용 특허 :
64 |
초록
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A lens for placement in a human eye, such as intraocular lens, has at least some of its optical properties formed with a laser. The laser forms modified loci in the lens when the modified loci have a different refractive index than the refractive index of the material before modification. Different
A lens for placement in a human eye, such as intraocular lens, has at least some of its optical properties formed with a laser. The laser forms modified loci in the lens when the modified loci have a different refractive index than the refractive index of the material before modification. Different patterns of modified loci can provide selected dioptic power, toric adjustment, and/or aspheric adjustment provided. Preferably both the anterior and posterior surfaces of the lens are planar for ease of placement in the human eye.
대표청구항
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1. A lens sized for use in a human eye comprising: a) a body formed of a polymeric optical material having a first refractive index, the body having opposed anterior and posterior surfaces and an optical axis; andb) a plurality of contiguous modified loci configured in a contiguous patterned microst
1. A lens sized for use in a human eye comprising: a) a body formed of a polymeric optical material having a first refractive index, the body having opposed anterior and posterior surfaces and an optical axis; andb) a plurality of contiguous modified loci configured in a contiguous patterned microstructure formed in a layer of the body, the polymeric optical material of the modified loci having a second refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, each modified locus being right cylindrically shaped and having an axis substantially parallel to the optical axis and an axial depth of at least 5 μm;wherein the contiguous patterned microstructure of modified loci adjusts an optical effect of the lens. 2. The lens of claim 1, wherein the contiguous patterned microstructure comprises a refractive structure. 3. The lens of claim 1, wherein the contiguous patterned microstructure comprises a refractive with phase wrapping structure. 4. The lens of claim 1, wherein the contiguous patterned microstructure comprises a refractive without phase wrapping structure. 5. The lens of claim 1, wherein the contiguous patterned microstructure comprises a diffractive phase structure. 6. The lens of claim 1, wherein the contiguous patterned microstructure comprises an annular ring pattern. 7. The lens of claim 1, wherein the optical effect comprises changing the diopter power of the body by at least plus or minus 0.5. 8. The lens of claim 1, wherein at least some of the modified loci have an optical path length of from 0.1 to about 1 wavelength greater than the optical path length of a non-modified locus, wherein the wavelength is with respect to light of wavelength of 555 nm. 9. The lens of claim 1, wherein at least some of the modified loci are configured in a substantially circular pattern around the optical axis. 10. The lens of claim 1, wherein the body includes sufficient modified loci configured in the contiguous patterned microstructure formed in the layer that at least 90% of light projected onto the anterior surface in a direction generally parallel to the optical axis passes through at least one modified locus. 11. The lens of claim 1, wherein there are at least 1,000,000 modified loci in the contiguous patterned microstructure formed in the layer of the body. 12. The lens of claim 1, wherein the layer is substantially perpendicular to the optical axis. 13. The lens of claim 12 further comprising a second layer that is substantially perpendicular to the optical axis, wherein there are at least two modified loci in the second layer and the second layer is spaced apart from the first layer. 14. The lens of claim 1, wherein both the posterior and anterior surfaces are substantially planar. 15. The lens of claim 1 wherein the material includes a UV light absorber of at least 0.01% by weight. 16. The lens of claim 15 wherein the UV light absorber comprises a yellow dye that absorbs at a wavelength of 390 nm. 17. The lens of claim 1 sized to be an intraocular lens. 18. The lens of claim 17 wherein the body has at least one haptic. 19. The lens of claim 1 wherein substantially all optical effects provided by the lens are provided by the modified loci. 20. The lens of claim 1 wherein the optical effect comprises a diopter power of from about −15 to about +42. 21. The lens of claim 1 wherein the optical effect provides a toric adjustment to the lens. 22. The lens of claim 1 wherein the optical effect provides an aspheric adjustment to the lens. 23. The lens of claim 1 wherein at least one of the surfaces is substantially convex. 24. The lens of claim 23 wherein at least one of the surfaces is substantially concave. 25. The lens of claim 1 wherein at least one of the surfaces is substantially concave. 26. The lens of claim 1 wherein the body is disc shaped. 27. The lens of claim 1 wherein the optical effect comprises a diopter power of at least 15. 28. The lens of claims 1 wherein the maximum thickness of the body is from about 50 to about 400 μm. 29. The lens of claim 28 wherein the maximum thickness of the body is about 250 μm. 30. The lens of claim 1 wherein each modified locus has from 1 to 10 sites, the sites being arranged in an axial direction, each site being formed by a single laser burst. 31. The lens of claim 1 wherein each modified locus has a diameter of about 1 μm and an axial depth of no more than about 50 μm. 32. The lens of claim 31 wherein each modified locus has an axial depth of from 5 to 50 μm. 33. The lens of claim 31 wherein the modified loci have axial depths varying from about 5 to 50 μm. 34. The lens of claim 1 wherein the layer has a thickness of about 50 μm. 35. The lens of claim 34 further comprising a second planar layer having a thickness of about 50 μm, wherein there are at least two modified loci in the second layer and the second layer is spaced apart from the first layer by at least one micron. 36. The lens of claim 35 wherein, the second layer is spaced apart from the first layer by at least five microns. 37. The lens of claim 35 wherein each modified locus in the second layer has an axial depth of at least five microns. 38. The lens of claim 35 wherein each modified locus has from 1 to 10 sites, the sites being arranged in an axial direction, each site being formed by a single laser burst. 39. A lens sized for use in a human eye comprising: a) a body formed of a polymeric optical material having a first refractive index, the body having opposed anterior and posterior surfaces and an optical axis, and comprising a first planar layer that is substantially perpendicular to the optical axis;b) a plurality of contiguous modified loci configured in a contiguous patterned microstructure formed in the first layer, the polymeric optical material of the modified loci having a second refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, wherein each modified locus is right cylindrically shaped and has an axis substantially parallel to the optical axis and an axial depth of at least 5 μm;wherein the contiguous patterned microstructure of modified loci in the first layer adjusts an optical effect of the lens. 40. The lens of claim 39, wherein the contiguous patterned microstructure comprises a refractive structure. 41. The lens of claim 39, wherein the contiguous patterned microstructure comprises a refractive with phase wrapping structure. 42. The lens of claim 39, wherein the contiguous patterned microstructure comprises a refractive without phase wrapping structure. 43. The lens of claim 39, wherein the contiguous patterned microstructure comprises a diffractive phase structure. 44. The lens of claim 39, wherein the contiguous patterned microstructure includes an annular ring pattern. 45. The lens of claim 39 wherein the lens has sufficient modified loci configured in the contiguous patterned microstructure formed in the first layer that at least 90% of light projected onto the anterior surface in a direction generally parallel to the optical axis passes through at least one modified locus. 46. The lens of claim 39 wherein there are at least 1,000,000 modified loci in the contiguous patterned microstructure formed in the first layer of the body. 47. The lens of claim 39 sized to be an intraocular lens. 48. The lens of claim 47 wherein the body has at least one haptic. 49. The lens of claim 39 wherein substantially all optical effects provided by the lens are provided by the modified loci. 50. The lens of claim 39 wherein the optical effect comprises a diopter power of from about −15 to about +42. 51. The lens of claim 39 wherein the optical effect provides a toric adjustment to the lens. 52. The lens of claim 39 wherein the optical effect provides an aspheric adjustment to the lens. 53. The lens of claim 39 wherein at least one of the surfaces is substantially convex. 54. The lens of claim 53 wherein at least one of the surfaces is substantially concave. 55. The lens of claim 39 wherein at least one of the surfaces is substantially concave. 56. The lens of claim 39 wherein the body is disc shaped. 57. The lens of claim 39 wherein the optical effect comprises a diopter power of at least 15. 58. The lens of claims 39 wherein the maximum thickness of the body is from about 50 to about 400 μm. 59. The lens of claim 58 wherein the maximum thickness of the body is about 250 μm. 60. The lens of claim 39 wherein each modified locus has a diameter of about 1 μm and an axial depth of no more than about 50 μm. 61. The lens of claim 60 wherein each modified locus has an axial depth of from 5 to 50 μm. 62. The lens of claim 60 wherein each modified locus has from 1 to 10 sites, the sites being arranged in an axial direction, each site being formed by a single laser burst. 63. The lens of claim 60 wherein the modified loci have axial depths varying from about 5 to 50 μm. 64. The lens of claim 39 wherein the first layer has a thickness of about 50 μm. 65. The lens of claim 64 further comprising a second planar layer having a thickness of about 50 μm, wherein there are at least two modified loci in the second layer and the second layer is spaced apart from the first layer by at least one micron. 66. The lens of claim 65 wherein, the second layer is spaced apart from the first layer by at least five microns. 67. The lens of claim 65 wherein each modified locus in the second layer has an axial depth of at least five microns. 68. The lens of claim 65 wherein each modified locus has from 1 to 10 sites, the sites being arranged in an axial direction, each site being formed by a single laser burst. 69. The lens of claim 39 wherein the material includes a UV light absorber of at least 0.01% by weight. 70. The lens of claim 69 wherein the UV light absorber comprises a yellow dye that absorbs light at a wavelength of 390 nm. 71. An achromatic lens sized for use as an intraocular lens comprising: a) a body formed of a polymeric optical material having a first refractive index, the body having opposed anterior and posterior surfaces and an optical axis, and comprising first and second planar layers that are substantially perpendicular to the optical axis;b) a first plurality of contiguous modified loci configured in a first contiguous patterned microstructure formed in the first layer in the body, the polymeric optical material of the modified loci in the first layer having a second refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, wherein at least some of modified loci in the first layer have an optical path length of at least 0.1 wavelength greater than the optical path length of a non-modified locus, and wherein the wavelength is with respect to light of a first wavelength; andc) a second plurality of contiguous modified loci configured in a second contiguous patterned microstructure formed in the second layer in the body, the polymeric optical material of the modified loci in the second layer having a third refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, wherein at least some of the modified loci in the second layer have an optical path length of at least 0.1 wavelength greater than the optical path length of a non-modified locus, and wherein the wavelength is with respect to light of a second wavelength different from the first wavelength by at least 50 nm;wherein each modified locus in the first and second layers is right cylindrically shaped and has an axis substantially parallel to the optical axis and an axial depth of at least 5 μm. 72. The lens of claim 71 wherein light of the first wavelength is green light and light of the second wavelength is red light. 73. The lens of claim 71 wherein the thickness of the each layer is about 50 μm. 74. The lens of claim 73 wherein the layers are spaced apart from one another by at least one micron. 75. The lens of claim 73 wherein the layers are spaced apart from one another by at least 5 microns. 76. The lens of claims 71 wherein the material includes a UV light absorber of at least 0.01% by weight. 77. The lens of claim 76 wherein the UV light absorber comprises a yellow dye that absorbs light at a wavelength of 390 nm. 78. The lens of claim 71 further comprising a third plurality of contiguous modified loci configured in a third contiguous patterned microstructure formed in a third layer in the body, the polymeric optical material of the modified loci in the third layer having a fourth refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, wherein each modified locus in the third layer is right cylindrically shaped and has an axis substantially parallel to the optical axis and an axial depth of at least 5 μm, and at least some of modified loci in the third layer have an optical path length of at least 0.1 wavelength greater than the optical path length of a non-modified locus, wherein the wavelength is with respect to light of a third wavelength, the third wavelength being different from the first wavelength by at least 50 nm and different from the second wavelength by at least 50 nm. 79. The lens of claim 78 wherein the light of the first wavelength is green light, light of the second wavelength is red light, and light of the third wavelength is blue light. 80. The lens of claim 78 wherein the thickness of the each layer is about 50 μm. 81. The lens of claim 80 wherein the layers are spaced apart from one another by at least one micron. 82. The lens of claim 80 wherein the layers are spaced apart from one another by at least 5 microns. 83. The lens of claims 78 wherein the material includes a UV light absorber of at least 0.01% by weight. 84. The lens of claim 83 wherein the UV light absorber comprises a yellow dye that absorbs light at a wavelength of 390 nm. 85. A multi-focal lens sized for placement in a human eye comprising: a) a body formed of a polymeric optical material having a first refractive index, the body having opposed anterior and posterior surfaces and an optical axis, and comprising first and second layers that are each substantially perpendicular to the optical axis;b) a first plurality of contiguous modified loci configured in a first contiguous patterned microstructure formed in the first layer of the body, each modified locus in the first plurality being right cylindrically shaped and having an axis substantially parallel to the optical axis and an axial depth of at least 5 μm, the polymeric optical material of the first plurality of modified loci in the first layer having a second refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, wherein at least some of the first plurality of modified loci in the first layer have an optical path length of at least 0.1 wavelength greater than the optical path length of a non-modified locus in the first layer, wherein the first plurality of contiguous modified loci in the first layer focus light transmitted therethrough at a first focal spot; andc) a second plurality of contiguous modified loci configured in a second contiguous patterned microstructure formed in the second layer of the body, each modified locus in the second plurality being right cylindrically shaped and having an axis substantially parallel to the optical axis and an axial depth of at least 5 μm, the polymeric optical material of the second plurality of modified loci in the second layer having a third refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, wherein at least some of the second plurality of modified loci in the second layer have an optical path length of at least 0.1 wavelength greater than the optical path length of a non-modified locus in the second layer, wherein the second plurality of contiguous modified loci in the second layer focus light transmitted therethrough at a second focal spot spaced apart from the first focal spot. 86. The lens of claim 85 further comprising a third layer that is substantially perpendicular to the optical axis, the third layer having a third plurality of contiguous modified loci configured in a third contiguous patterned microstructure formed therein, each modified locus in the third plurality being right cylindrically shaped and having an axis substantially parallel to the optical axis and an axial depth of at least 5 μm, the polymeric optical material of the third plurality of modified loci in the third layer having a fourth refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, wherein at least some of the third plurality of modified loci in the third layer have an optical path length of at least 0.1 wavelength greater than the optical path length of a non-modified locus adjacent to the modified locus in the third layer, wherein the third plurality of contiguous modified loci in the third layer focus light transmitted therethrough at a third focal spot spaced apart from both the first and second focal spots. 87. The lens of claim 85 wherein the polymeric optical material of the body comprises a polymeric matrix and an absorber for UV light of the laser light wavelength. 88. The lens of claim 87 wherein the polymeric optical material of the body includes a UV light absorber of at least 0.01% by weight. 89. An achromatic lens sized for use in a human eye comprising: a) a body formed of a polymeric optical material having a first refractive index, the body having opposed anterior and posterior surfaces and an optical axis, and comprising first and second layers that are each substantially perpendicular to the optical axis;b) a first plurality of contiguous modified loci configured in a first contiguous patterned microstructure formed in the first layer of the body, each modified locus in the first layer being right cylindrically shaped and having an axis substantially parallel to the optical axis and an axial depth of at least 5 μm, the polymeric optical material of the first plurality of modified loci in the first layer having a second refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, wherein at least some of the first plurality of contiguous modified loci in the first layer have an optical path length of at least 0.1 wavelength greater than the optical path length of a non-modified locus in the first layer, and wherein the first plurality of contiguous modified loci in the first layer provide a diopter adjustment; andc) a second plurality of contiguous modified loci configured in a second contiguous patterned microstructure formed in the second layer of the body, each modified locus in the second layer being right cylindrically shaped and having an axis substantially parallel to the optical axis and an axial depth of at least 5 μm, the polymeric optical material of the second plurality of modified loci in the second layer having a third refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, wherein at least some of the second plurality of contiguous modified loci in the second layer have an optical path length of at least 0.1 wavelength greater than the optical path length of a non-modified locus in the second layer, and wherein the second plurality of contiguous modified loci in the second layer provide at least one of a toric adjustment and aspheric adjustment. 90. The lens of claim 89 wherein the second plurality of contiguous modified loci in the second layer provides a toric adjustment, and further comprising a third layer that is substantially perpendicular to the optical axis, the third layer including a third plurality of contiguous modified loci configured in a third contiguous patterned microstructure formed therein, each modified locus in the third layer being right cylindrically shaped and having an axis substantially parallel to the optical axis and an axial depth of at least 5 μm, the polymeric optical material of the third plurality of contiguous modified loci in the third layer having a fourth refractive index, which is different from the first refractive index and caused by nonlinear absorption of photons resulting from exposure to focused laser light, wherein at least some of the third plurality of contiguous modified loci in the third layer have an optical path length of at least 0.1 wavelength greater than the optical path length of a non-modified locus in the third layer, and wherein the third plurality of contiguous modified loci in the third layer provides an aspheric adjustment.
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