IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0853139
(2010-08-09)
|
등록번호 |
US-8323311
(2012-12-04)
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발명자
/ 주소 |
|
출원인 / 주소 |
- Abbott Laboratories Vascular Enterprises Limited
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
2 인용 특허 :
12 |
초록
▼
The apparatus is provided for sealing a vascular puncture tract by forming the autologous plug within the puncture tract, and extruding that plug into the puncture tract. The apparatus of the present invention forms an autologous blood plug by drawing blood into the apparatus from a vessel, mixing a
The apparatus is provided for sealing a vascular puncture tract by forming the autologous plug within the puncture tract, and extruding that plug into the puncture tract. The apparatus of the present invention forms an autologous blood plug by drawing blood into the apparatus from a vessel, mixing a blood congealing agent with the drawn blood, and ejecting a plug formed from the clotted blood within the puncture tract. Also provided are various closure elements to isolate the drawn blood from the vessel during mixture with the blood congealing agent, and to facilitate placement of the apparatus relative to the vessel.
대표청구항
▼
1. A device for sealing a puncture tract by forming and extruding an autologous plug within the puncture tract, the device comprising: a housing having a lumen adapted to mix a volume of blood with a blood congealing agent to form the autologous plug;a selectively closable iris cooperating with a di
1. A device for sealing a puncture tract by forming and extruding an autologous plug within the puncture tract, the device comprising: a housing having a lumen adapted to mix a volume of blood with a blood congealing agent to form the autologous plug;a selectively closable iris cooperating with a distal opening of the lumen of the housing, the selectively closable iris is configured to be inserted into the puncture tract and to isolate the mixture of the volume of blood and the blood congealing agent from the vessel during formation of the autologous plug within the lumen; anda plunger disposed for translation within the lumen to extrude the autologous plug formed within the lumen. 2. The device of claim 1, wherein the housing comprises a second lumen to facilitate placement of a distal end of the device. 3. The device of claim 1, wherein the housing comprises an inner tube forming the lumen and an outer tube substantially extending along an axial length of the inner tube, wherein relative rotation between the inner tube and the outer tube moves the selectively closable iris between a first position, wherein the distal opening of the lumen is exposed, and a second position, wherein the distal opening of the lumen is substantially sealed by the selectively closable iris. 4. The device of claim 3, wherein the inner tube is axially fixed relative to the outer tube. 5. The device of claim 1, wherein the autologous plug formed in the lumen has a length and a form factor that causes the autologous plug to engage tissue surrounding the puncture tract after ejection by the plunger into the puncture tract. 6. The device of claim 1, wherein the selectively closable iris a plate having a plurality of tracks and an opening disposed therethrough, and a plurality of blades operably engaged to the plurality of tracks. 7. The device of claim 1, wherein the blood congealing agent is pre-disposed within the lumen. 8. The device of claim 7, wherein the blood congealing agent is coated onto an interior surface of the lumen. 9. The device of claim 1, wherein the blood congealing agent is introduced into the lumen subsequent to actuation of the selectively closable iris. 10. The device of claim 9, wherein the blood congealing agent comprises a platinum wire. 11. The device of claim 10, wherein the blood congealing agent comprises a thermo-resistive wire. 12. The device of claim 1, wherein the blood congealing agent is chosen from the group consisting of thrombin, fibrin, human factor VIII, and combinations thereof. 13. The device of claim 1, wherein the blood congealing agent comprises a matrix. 14. The device of claim 13, wherein the matrix is chosen from the group consisting of gauze, biocompatible foam, and spun fiber. 15. The device of claim 13, wherein the matrix is biodegradable. 16. The device of claim 13, wherein the matrix has a cross-sectional geometry at least partially defining a plurality of longitudinal channels and at least one inner lumen disposed therethrough. 17. A device for sealing a puncture tract by forming and extruding an autologous plug within the puncture tract, the device comprising: a housing having a lumen adapted to mix a volume of blood with a blood congealing agent;a membrane cooperating with the lumen of the housing that is permeable to blood and impermeable to the blood congealing agent, the membrane is configured to be inserted into the puncture tract and to isolate the mixture of the volume of blood and the blood congealing agent from the vessel during formation of the autologous plug; anda plunger disposed for translation within the lumen to extrude the autologous plug formed within the lumen. 18. A device for sealing a puncture tract by forming and extruding an autologous plug within the puncture tract, the device comprising: a housing including an inner tube forming a central lumen adapted to mix a volume of blood with a blood congealing agent, and an outer tube forming an annular lumen between the inner tube and the outer tube, the annular lumen extending substantially along an axial length of the inner tube;a closure element cooperating with a distal opening of the central lumen, the closure element is configured to be inserted into the puncture tract and to isolate the mixture of the volume of blood and the blood congealing agent from the vessel during formation of the autologous plug within the central lumen, wherein relative rotation between the inner tube and the outer tube moves the closure element between a first position, wherein the distal opening of the central lumen is exposed, and a second position, wherein the distal opening of the central lumen is substantially sealed by the closure element; anda plunger disposed for translation within the central lumen to extrude the autologous plug formed within the lumen. 19. The device of claim 18, wherein the annular lumen is in fluid communication with the central lumen via a plurality of apertures disposed through and along the axial length of the inner tube. 20. The device of claim 18, wherein the closure element comprises first and second plates, each of the first and second plates having a plurality of through-wall slots, the first and second plates being relatively rotatable to selectively align the pluralities of through-wall slots.
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