A system relating to sample analyzers, and more particular, to sample analyzers that are simple to operate and have a reduced risk of providing an erroneous result to a user. In some cases, the sample analyzer may be a portable sample analyzer that includes a disposable fluidic cartridge. The operat
A system relating to sample analyzers, and more particular, to sample analyzers that are simple to operate and have a reduced risk of providing an erroneous result to a user. In some cases, the sample analyzer may be a portable sample analyzer that includes a disposable fluidic cartridge. The operators of the analyzers need not be trained.
대표청구항▼
1. A sample analyzer comprising: an instrument having a slot; anda cartridge including a flow channel, the cartridge configured to be inserted into the slot;a light source positioned on a first side of the flow channel proximate to the cartridge when inserted in the slot; anda detector positioned on
1. A sample analyzer comprising: an instrument having a slot; anda cartridge including a flow channel, the cartridge configured to be inserted into the slot;a light source positioned on a first side of the flow channel proximate to the cartridge when inserted in the slot; anda detector positioned on the first side of the flow channel proximate to the cartridge when inserted in the slot; andwherein:the flow channel comprises a channel wall;the channel wall has a first index of refraction;a sample fluid in the flow channel has a second index of refraction;the light source is for projecting light into the flow channel; andthe detector is configured to detect light reflected from an interface of the first and second indices of refraction and the light detected by the detector is indicative of the index of refraction of the fluid. 2. The analyzer of claim 1, wherein: if the index of refraction of the fluid is not within a specified range, then the sample analyzer may not perform an analysis, not provide a result, indicate an incorrect fluid, and/or provide an error indication. 3. The analyzer of claim 1, wherein the channel wall is thin enough to permit optical tunneling if a delta between the first and second indices of refraction is within a range for the fluid to be satisfactory. 4. The analyzer of claim 1, wherein if the index of refraction of the fluid is not within the specified range the fluid may be a incorrect specimen or sample, have an incorrect reagent, bubbles, clots, contaminants, and/or the like. 5. The analyzer of claim 1, wherein: the detector is for detecting light going through the channel wall and the fluid and out of the channel through the channel wall;the light to the detector is indicative of an index of refraction of the fluid; andif the index of refraction of the volume is not within a specified range for an appropriate sample fluid, then the sample analyzer may not perform an analysis, not provide a result, indicate an incorrect sample fluid, and/or provide an error indication. 6. A sample analyzer comprising: an instrument having a slot, an energy source and a detector; anda cartridge, having at least one flow channel, for insertion into the slot;wherein: the energy source and detector are positioned on a same side of the flow channel and adjacent to the flow channel; andthe detector is configured to detect a property of a fluid in the flow channel indicative of undesirable particles or bubbles in the fluid in the flow channel. 7. The analyzer of claim 6, wherein: the energy source is for providing light through the flow channel at an angle relative to a wall of the flow channel;the detector is for detecting a magnitude of scattered light from the flow channel;a magnitude of a certain range is indicative of undesirable particles or bubbles in a fluid in the flow channel; andif the magnitude of the certain range is detected, then the analyzer may not provide a result or may provide an error indication. 8. The analyzer of claim 6, wherein: the energy source is an ultrasound transducer, adjacent to the flow channel, for transmitting ultrasound into the flow channel;the detector is an ultrasound receiver, adjacent to the flow channel, for receiving reflected ultrasound energy from the flow channel;reflected ultrasound energy having a magnitude of a certain range is indicative of bubbles or other undesirable particles in the flow channel; andif reflected ultrasound energy having a magnitude of a certain range is received by the ultrasound receiver, then the analyzer would not provide a result and/or would provide an error indication. 9. The analyzer of claim 6, wherein: the energy source is a pressure source for applying a certain change of pressure to a sample fluid in the flow channel;the detector is a flow sensor, situated in the flow channel, for monitoring a flow rate in the flow channel;a flow rate of the sample fluid is monitored by the flow sensor while a certain change of pressure is applied by the pressure source to the fluid in the flow channel;a flow rate change per unit of time for the certain change of pressure indicates an amount of compressibility of the sample fluid; andthe amount of compressibility of a specific range is indicative of bubbles in the sample fluid. 10. The analyzer of claim 9, wherein the pressure source is a high frequency pulse piezoresistive pressure source. 11. The analyzer of claim 9, if bubbles are indicated to be in the sample fluid in the flow channel, the analyzer will not provide a result and/or will provide an error indication. 12. The analyzer of claim 6, wherein: the energy source is a pressure transducer for transmitting a pressure pulse in a sample fluid in the flow channel, at a first location along the flow channel to a terminal end of the sample fluid;the detector is a pressure receiver for receiving the pressure pulse reflected by the terminal end of the fluid, at a second location along the flow channel; anda duration of time between transmitting a pressure pulse down the flow channel and receiving the reflected pulse is indicative of a location of the terminal end along the flow channel relative to the first and second locations. 13. The analyzer of claim 6, wherein: the energy source is a pressure transducer for transmitting a pressure pulse in a sample fluid in the flow channel, at a first location along the flow channel to a terminal end of the sample fluid;the detector is a pressure receiver for receiving the pressure pulse reflected by the terminal end of the fluid, at a second location along the flow channel; anda duration of time between transmitting a pressure pulse down the flow channel and receiving the reflected pulse is indicative of a location of the terminal end along the flow channel relative to the first and second locations. 14. The analyzer of claim 6, wherein: the energy source is a pressure transducer for transmitting a pressure pulse in a first fluid in a first flow channel;the detector is a pressure receiver for receiving the pressure pulse from a second fluid in a second flow channel;a first fluid having a terminal end is in the first flow channel;a second fluid having a terminal end is in the second flow channel; andif a pressure pulse is produced in the first fluid by the pressure transducer, a significant pressure pulse signal will appear at the pressure receiver upon a meeting of the terminal ends of the first and second fluids.
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