Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrode assemblies that are implantable at sites proximate the myocardium usi
Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrode assemblies that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Also disclosed are various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
대표청구항▼
1. An implantable wireless electrode assembly comprising: a first electrode configured to provide an electrostimulation to a myocardium of a heart;an attachment mechanism configured to secure at least a portion of the wireless electrode assembly to the myocardium, the attachment mechanism including
1. An implantable wireless electrode assembly comprising: a first electrode configured to provide an electrostimulation to a myocardium of a heart;an attachment mechanism configured to secure at least a portion of the wireless electrode assembly to the myocardium, the attachment mechanism including a distally extending helical tine, and at least one radially extending deformable tine, the helical tine configured to penetrate through the endocardium and into the myocardium, and the at least one radially extending deformable tine, including a sharp tip, configured to penetrate into the myocardium without penetrating entirely through the myocardium and beyond the epicardial wall opposite the interior heart wall; andwherein the at least one radially extending deformable tine includes a retracted substantially linear configuration and a user-actuatable extended curled configuration, and wherein the deformable tine is configured to be in the retracted substantially linear configuration when the helical tine is introduced into the myocardium, and wherein the deformable tine is user-actuatable to radially extend into the myocardium and curl without penetrating entirely through the myocardium and beyond the epicardial wall opposite the interior heart wall after the helical tine has been introduced into the myocardium. 2. The wireless electrode assembly of claim 1, comprising a second electrode spaced apart from the first electrode such that, when at least a portion of the attachment mechanism penetrates through endocardium and into the myocardium, the first electrode is positioned proximate to the myocardium while the second electrode is exposed to blood in an internal heart chamber. 3. The wireless electrode assembly of claim 2, comprising: an internal battery-free circuit; andan induction coil to wirelessly receive electromagnetic energy from an external source, wherein the first and second electrodes are configured to directly deliver a specified electrostimulation waveform to the myocardium using the battery-free circuit and using at least a portion of the electromagnetic energy received by the induction coil, and wherein the induction coil and the first and second electrodes are connected to the internal, battery-free circuit. 4. The wireless electrode assembly of claim 3, comprising a detachment mechanism configured to release the wireless electrode assembly from an intravascular delivery system after the wireless electrode assembly has been transluminally delivered to an interior of a heart chamber using the intravascular delivery system, and after at least a portion of the attachment mechanism penetrates through the endocardium and into the myocardium without penetrating entirely through the myocardium and beyond the epicardial wall opposite the interior heart wall. 5. The wireless electrode assembly of claim 4, wherein the detachment mechanism includes a threaded member. 6. The wireless electrode assembly of claim 3, wherein the internal, battery-free circuit is configured to provide the first and second electrodes with enough received electromagnetic energy to produce an electrostimulation waveform across the first and second electrodes having an amplitude greater than 0.5 Volts. 7. The wireless electrode assembly of claim 6, wherein the electrostimulation waveform amplitude is about 2 Volts. 8. The wireless electrode assembly of claim 6, wherein the electrostimulation waveform provided by the first and second electrodes includes a pulse duration of approximately 0.4 msec. 9. The wireless electrode assembly of claim 1, comprising an induction device to wirelessly receive electromagnetic energy from an external source, wherein the first electrode and the induction device are electrically connected to a circuit configured to provide electrostimulation energy to the first electrode using at least a portion of the electromagnetic energy received by the induction device. 10. The wireless electrode assembly of claim 9, wherein the circuit includes an energy storage element to store the electromagnetic energy received by the induction device, the energy storage element configured to periodically discharge electrical energy to be delivered as a specified electrostimulation waveform to the myocardium by the electrode. 11. The wireless electrode assembly of claim 9, wherein the induction device includes a coil that is inductively coupled to the external source. 12. The wireless electrode assembly of claim 1, comprising a detachment mechanism including a threaded member configured to release the wireless electrode assembly from an intravascular delivery system after the wireless electrode assembly has been transluminally delivered to an interior of a heart chamber using the intravascular delivery system, and after at least a portion of the attachment mechanism penetrates through endocardium and into the myocardium without penetrating entirely through the myocardium and beyond the epicardial wall opposite the interior heart wall. 13. The wireless electrode assembly of claim 1, comprising a second electrode spaced apart from the first electrode, wherein, when the attachment mechanism at least partially penetrates through the endocardium of the heart and into the myocardium without penetrating entirely through the myocardium and beyond the epicardial wall opposite the interior heart wall, the first electrode is positioned at least partially in the myocardium while the second electrode is exposed to an interior chamber of the heart. 14. The wireless electrode assembly of claim 1, wherein the deformable tine is user-actuatable to radially extend from the retracted substantially linear configuration from within a body portion of the wireless electrode assembly into the extended curled configuration in the myocardium without penetrating entirely through the myocardium and beyond the epicardial wall opposite the interior heart wall, after the helical tine has been introduced into the myocardium. 15. The wireless electrode assembly of claim 1, wherein the deformable tine is configured to self-bias, in response to actuation by the user to extend the deformable tine, from the retracted substantially linear configuration into the extended curled configuration.
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