초록 ▼

A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnos

A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and/or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and/or halt the delivery of medication to the patient until the alert is resolved.

대표청구항 ▼

1. A system for managing therapy provided to a patient, comprising: a two-way communication system;a database coupled to the communication system, the database comprising: a pharmacokinetic (PK) model configured to predict a concentration of at least one medication within at least a portion of the p

1. A system for managing therapy provided to a patient, comprising: a two-way communication system;a database coupled to the communication system, the database comprising: a pharmacokinetic (PK) model configured to predict a concentration of at least one medication within at least a portion of the patient's body tissue; andone or more limits for the concentration of the medication within the patient's body tissue;a medication delivery device comprising: a memory configured to store programs;a communication means coupled to the communication system; anda processor coupled to the memory and the communication means, the processor configured to retrieve the programs from the memory and operate the medication delivery device according to the programs to deliver medication to the patient at an adjustable rate, the processor further configured to accept input of delivery parameters; anda server coupled to the communication system and configured to: receive the delivery parameters from the medication delivery device;retrieve the PK model and limits from the database;utilize the PK model with the delivery parameters to predict the concentration of the medication within the body tissue of the patient if the medication is administered according to the retrieved delivery parameters;compare the predicted concentration to the concentration limits; andprovide an alert if the predicted concentration is outside any of the concentration limits. 2. The system of claim 1, wherein the server is further configured to: accept one or more laboratory test results; andmodify one or more of the concentration limits based on laboratory test results. 3. The system of claim 1, wherein the server is further configured to: accept patient-specific information comprises at least one of the group of an age, a weight, a gender, a diagnosis, a blood pressure, a result of a blood test, and a result of a urine test; andutilize the PK model with the patient-specific information. 4. The system of claim 1, wherein: the database further comprises: a pharmacodynamic (PD) model configured to predict a physiological response based on the concentration of the medication in the patient's body tissues; andone or more limits for the physiological response; andthe server is further configured to: accept a measurement of the physiological response;utilize the PD model to predict the physiological response based on the medication concentration predicted by the PK model;compare the predicted physiological response to the measured physiological response; andprovide an alert if the difference between the measured physiological response and the predicted physiological response exceeds any of the physiological response limits.