Compositions comprising a UV-absorbing chromophore
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-008/00
A61K-008/18
A61Q-017/04
출원번호
US-0776876
(2010-05-10)
등록번호
US-8357353
(2013-01-22)
발명자
/ 주소
Laszlo, Joseph A.
Compton, David L.
DeFilippi, Louis J.
Grall, Steven
출원인 / 주소
Biotechnology Research & Development Corporation
인용정보
피인용 횟수 :
0인용 특허 :
17
초록▼
A chemical composition comprising a linker agent and a compound comprising at least one UV-absorbing chromophore, wherein the linker agent is characterized by the general formula: wherein X1 and X2 are the same or different, and at least one of X1 or X2 is a functional group that bonds with the com
A chemical composition comprising a linker agent and a compound comprising at least one UV-absorbing chromophore, wherein the linker agent is characterized by the general formula: wherein X1 and X2 are the same or different, and at least one of X1 or X2 is a functional group that bonds with the compound comprising at least one UV-absorbing chromophore, and b+f≧2, Y comprises an O, N, or S that is substituted or unsubstituted, each a, b, c, e and f is ≧0 and a+b+c+e+f≧2, d is 0 or 1, n1 and n2 represent the number of hydrogen atoms required to complete the undesignated valencies, and m ranges from 1 to about 100 and each individual m unit may be the same or different.
대표청구항▼
1. A composition comprising a compound having a formula I: wherein:at least one of X1 and X2 is present; X1 and X2 are the same or different; at least one of X1 or X2 has at least one UV-absorbing chromophore; and b+f≧2;at least one of X3 and X4 is present; X3 and X4 are the same or different and ar
1. A composition comprising a compound having a formula I: wherein:at least one of X1 and X2 is present; X1 and X2 are the same or different; at least one of X1 or X2 has at least one UV-absorbing chromophore; and b+f≧2;at least one of X3 and X4 is present; X3 and X4 are the same or different and are selected from the group consisting of a moiety characterized by the formula: —CH═CH—(CH2)nCH3 where n ranges from 8 to 24; a moiety characterized by the formula: —NCO—(CH2)—CH═CH—(CH2)7CH3; a sphingosine; a ceramide; and combinations thereof;Y comprises an O, N, or S that is substituted or unsubstituted;each a, b, c, e and f is ≧0 and a+b+c+e+f≧2;d is 0 or 1;n1, n2, n3, n4, n5, and n6 represent the number of hydrogen atoms required to complete the undesignated valencies; andm ranges from 1 to 100 and each individual m unit is the same or different. 2. The composition of claim 1 wherein the compound having at least one UV-absorbing chromophore is a phytochemical. 3. The composition of claim 2 wherein the phytochemical has a carboxyl containing group. 4. The composition of claim 1 having anti-aging properties, anti-neoplastic properties, antibacterial properties, antioxidant properties, or combinations thereof. 5. The composition of claim 2 wherein the phytochemical is selected from the group consisting of an aromatic species, an unsaturated isoprenoid, an unsaturated terpenoid, a hindered hydroxy-substituted cinnamic acid, and an unhindered hydroxy-substituted cinnamic acid. 6. The composition of claim 2 wherein the phytochemical is selected from the group consisting of maleanilic acid, homovanillic acid, folic acid, crocetin, coumaric acid, caffeic acid, ferulic acid, and sinapic acid (sinapinic acid). 7. The composition of claim 1 wherein the X3, X4 or both are selected from the group consisting of a sphingosine, a ceramide and combinations thereof. 8. The composition of claim 1 wherein the Ca-Cb-Cc—(Y)d—Cc-Cf portion of formula I is a sphingosine or a ceramide. 9. The composition of claim 1 wherein X1 or X2 is ferulic acid and the ferulic acid provides the at least one UV-absorbing chromophore. 10. The composition of claim 1 wherein X1 and X2 are ferulic acid and the ferulic acid provides the at least one UV-absorbing chromophore. 11. The composition of claim 9 wherein X1, X2, or both are ferulic acid and the ferulic acid provides the at least one UV-absorbing chromophore. 12. A product for topical application comprising the composition of claim 1. 13. A product comprising the composition of claim 1, wherein the product is a lotion, a sunscreen, a cosmetic product, an agrochemical, a pharmaceutical, a nutritional product or combinations thereof. 14. The composition of claim 5 wherein the Ca-Cb-Cc—(Y)d—Ce-Cf portion of formula I is a sphingosine or a ceramide. 15. The composition of claim 5 wherein X1 or X2 comprises ferulic acid and the ferulic acid provides the at least one UV-absorbing chromophore. 16. The composition of claim 14 wherein X1 or X2 comprises ferulic acid and the ferulic acid provides the at least one UV-absorbing chromophore. 17. A product comprising the composition of claim 5, wherein the product is a lotion, a sunscreen, a cosmetic product, an agrochemical, a pharmaceutical, a nutritional product or combinations thereof. 18. A product containing the composition of claim 5, wherein the composition has at least two different compounds having the formula I, wherein the product is a lotion, a sunscreen, a cosmetic product, an agrochemical, a pharmaceutical, a nutritional product or combinations thereof. 19. A composition comprising a compound having a formula I: wherein: at least one of X1 and X2 is present; and X1, X2, or both are ferulic acid, wherein the ferulic acid or provides at least one UV-absorbing chromophore; and b+f≧2;at least one of X3 and X4 is present; X3 and X4 are the same or different and are selected from the group consisting of a moiety characterized by the formula: —CH═CH—(CH2)nCH3 where n ranges from 8 to 24; a moiety characterized by the formula: —NCO—(CH2)—CH═CH—(CH2)7CH3; a sphingosine; a ceramide; and combinations thereof;Y comprises an O, N, or S that is substituted or unsubstituted;each a, b, c, e and f is ≧0 and a+b+c+e+f≧2;d is 0 or 1;n1, n2, n3, n4, n5, and n6 represent the number of hydrogen atoms required to complete the undesignated valencies; andm ranges from 1 to 100 and each individual m unit is the same or different. 20. The composition of claim 19 wherein the compound having the Ca-Cb-Cc—(Y)d—Ce-Cf portion of formula I is a sphingosine or a ceramide. 21. A product comprising the composition of claim 19, wherein the product is a lotion, a sunscreen, a cosmetic product, an agrochemical, a pharmaceutical, a nutritional product or combinations thereof.
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이 특허에 인용된 특허 (17)
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