최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0055227 (2008-03-25) |
등록번호 | US-8364230 (2013-01-29) |
발명자 / 주소 |
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출원인 / 주소 |
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인용정보 | 피인용 횟수 : 1 인용 특허 : 468 |
Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a
Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
1. A device for the detection of at least one analyte in a circulatory system of a host in vivo, comprising: an apparatus configured for fluid communication with the circulatory system of the host, wherein the apparatus comprises a lumen, an external surface, a first orifice and a second orifice, wh
1. A device for the detection of at least one analyte in a circulatory system of a host in vivo, comprising: an apparatus configured for fluid communication with the circulatory system of the host, wherein the apparatus comprises a lumen, an external surface, a first orifice and a second orifice, wherein at least one of the first orifice or the second orifice is configured to couple with a fluid flow device;at least one analyte sensor disposed within the lumen of the apparatus, wherein the at least one analyte sensor comprises at least one working electrode; andsensor electronics operably connected to the at least one sensor, wherein the sensor electronics comprise a module configured to detect a fluidics malfunction in the device by monitoring a pattern of signal increases or decreases generated on the at least working electrode. 2. The device of claim 1, wherein the at least one analyte sensor comprises a plurality of sensors, and wherein the apparatus further comprises a plurality of sensor sites, wherein each sensor site of the plurality of sensor sites is configured to receive a sensor of the plurality of sensors. 3. The device of claim 2, wherein at least one of the plurality of sensor sites comprises a breakaway portion configured for insertion of the sensor therethrough, whereby at least a portion of the sensor is disposed within the lumen. 4. The device of claim 3, wherein at least another portion of the sensor is disposed at the external surface. 5. The device of claim 1, wherein the apparatus is a vascular access device comprising an in vivo portion and an ex vivo portion, and wherein the at least one sensor is disposed within the ex vivo portion. 6. The device of claim 1, wherein the apparatus is configured to be disposed outside of the host's body. 7. The device of claim 1, wherein the at least one analyte sensor is configured to generate a signal associated with a concentration of an analyte in a sample from the host's circulatory system. 8. The device of claim 7, wherein the at least one analyte sensor comprises at least two sensors that are configured to generate signals associated with a concentration of at least one analyte. 9. The device of claim 7, wherein the analyte is selected from the group consisting of glucose, oxygen, lactate, glutamine, succinate, Cytochrome Oxidase, a medicament, and heparin. 10. The device of claim 1, wherein the at least one analyte sensor is configured to generate a signal associated with a property of a sample from the host's circulatory system. 11. The device of claim 1, wherein the at least one analyte sensor is disposed above a plane defined by the host's skin. 12. The device of claim 1, wherein the at least one sensor is integrally formed within the apparatus. 13. The device of claim 1, wherein the apparatus is a vascular access device comprising an in vivo portion and an ex vivo portion, and wherein the at least one sensor is disposed within the in vivo portion. 14. The device of claim 1, wherein the at least one analyte sensor is screen-printed within the lumen. 15. The device of claim 1, wherein the apparatus is injection molded around the at least one analyte sensor. 16. The device of claim 1, wherein the at least one analyte sensor comprises a first sensor and a second sensor. 17. The device of claim 16, wherein the first sensor comprises an enzymatic electrode and the second sensor comprises a non-enzymatic electrode. 18. The device of claim 1, wherein the apparatus is a fluid coupler, and wherein at least of one of the first orifice or the second orifice is configured to couple with a vascular access device. 19. The device of claim 18, wherein the fluid flow device comprises IV equipment. 20. The device of claim 1, wherein the signal pattern is compared to an expected waveform comprising an upper limit and a lower limit, and wherein the module is configured to detect the fluidic malfunction when the signal is above the upper limit or below the lower limit. 21. The device of claim 1, wherein the module is configured to evaluate the detected fluidics malfunction against a preprogrammed criterion. 22. The device of claim 1, wherein the module is configured to provide at least one of an alert, alarm, or an instruction responsive to detection of the fluidics malfunction.
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