최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0210078 (2008-09-12) |
등록번호 | US-8374688 (2013-02-12) |
발명자 / 주소 |
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출원인 / 주소 |
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인용정보 | 피인용 횟수 : 80 인용 특허 : 370 |
An adherent device to monitor a tissue hydration of a patient comprises an adhesive patch to adhere to a skin of the patient. At least four electrodes are connected to the patch and capable of electrically coupling to the patient. Impedance circuitry is coupled to the at least four electrodes to mea
An adherent device to monitor a tissue hydration of a patient comprises an adhesive patch to adhere to a skin of the patient. At least four electrodes are connected to the patch and capable of electrically coupling to the patient. Impedance circuitry is coupled to the at least four electrodes to measure a tissue resistance of the patient, where the circuitry is configured to determine the tissue hydration in response to tissue resistance. The circuitry may comprise a processor system and the tissue resistance may correspond to a change in patient body fluid. The impedance circuitry is configured to measure the hydration signal using at least one low measurement frequency, which may be in the range of 0 to 10 kHz. Multiple measurement frequencies may be used and the hydration signal may include a tissue reactance measurement.
1. An adherent device to monitor a tissue hydration of a patient, the device comprising: an adhesive patch to adhere to a skin of the patient;at least four electrodes connected to the patch and capable of electrically coupling to the patient; andcircuitry coupled to the at least four electrodes to m
1. An adherent device to monitor a tissue hydration of a patient, the device comprising: an adhesive patch to adhere to a skin of the patient;at least four electrodes connected to the patch and capable of electrically coupling to the patient; andcircuitry coupled to the at least four electrodes to measure a tissue resistance of the patient at a plurality of frequencies greater than zero, wherein the circuitry is configured to determine the tissue hydration using the measured tissue resistance, and wherein the circuitry is configured to detect a low frequency droop in the tissue resistance and to, when low frequency droop is detected, temporarily suspend data collection based at least in part on the fact that the low frequency droop has been detected. 2. The adherent device of claim 1, wherein the circuitry comprises a processor system configured to determine the hydration of the patient in response to the tissue resistance. 3. The adherent device of claim 2, wherein the circuitry is further configured to determine the tissue hydration based on a tissue resistance measured at a single frequency. 4. The adherent device of claim 1, wherein the tissue resistance corresponds to a change in patient body fluid. 5. The adherent device of claim 4, further comprising a processor coupled to the circuitry, wherein the processor is configured to determine an amount of extracellular edema from the change in patient body fluid. 6. The adherent device of claim 1, wherein the circuitry is further configured to measure extracellular fluid. 7. The adherent device of claim 1, wherein the circuitry is further configured to measure a tissue reactance of the patient. 8. The adherent device of claim 1, wherein the circuitry is configured to measure the tissue resistance using at least one low measurement frequency. 9. The adherent device of claim 8, wherein the at least one low measurement frequency is in the range of 5 to 15 kHz. 10. The adherent device of claim 8, wherein the at least one low measurement frequency comprises a single measurement frequency used to determine the tissue hydration. 11. The adherent device of claim 10, wherein the single measurement frequency is less than 10 kHz. 12. The adherent device of claim 8, wherein the at least one low measurement frequency comprise multiple measurement frequencies. 13. The adherent device of claim 12, wherein the circuitry is further configured to measure a tissue reactance of the patient. 14. An adherent device to monitor a patient, the device comprising: an adhesive patch to adhere to a skin of the patient;at least four electrodes connected to the patch and capable of electrically coupling to the patient at a skin-electrode interface;impedance circuitry coupled to the at least four electrodes to measure a hydration signal of the patient, wherein the impedance circuitry is configured to measure multiple frequencies; anda processor coupled to the impedance circuitry configured to determine a quality of the skin-electrode interface based on multiple measurements of the hydration signal at frequencies below 50 kHz, wherein the processor is configured to measure a low frequency droop in the tissue resistance, and to, when low frequency droop is detected, temporarily suspend data collection based at least in part on the fact that the low frequency droop has been detected. 15. The adherent device of claim 14, wherein the hydration signal comprises a tissue resistance measurement and a tissue reactance measurement. 16. The adherent device of claim 15, wherein the processor is further configured to determine a quality of the skin-electrode interface from at least one of an ECG signal-to-noise ratio, a tissue reactance, and a tissue impedance measured between any two of the at least four electrodes. 17. A method of monitoring a patient, the method comprising: adhering an adhesive patch to a skin of the patient to couple at least four electrodes to the skin of the patient to form a skin-electrode interface;measuring a hydration signal of the patient at a plurality of frequencies greater than zero with impedance circuitry coupled to the at least four electrodes, wherein the hydration signal comprises a tissue resistance measurement;detecting a low frequency droop in the tissue resistance measurement;determining a hydration of the patient using the tissue resistance measurement; andtemporarily suspending data collection based at least in part on the fact that the low frequency droop has been detected. 18. The method of claim 17, wherein the tissue resistance measurement corresponds to a change in patient body fluid. 19. The method of claim 18, further comprising determining an amount of extracellular edema from the change in patient body fluid with a processor coupled to the impedance circuitry. 20. The method of claim 17, wherein the hydration signal is measured with at least one low measurement frequency. 21. The method of claim 20, wherein the at least one low measurement frequency is less than 10 kHz. 22. The method of claim 20, wherein the at least one low measurement frequency comprise a single measurement frequency used to determine the tissue hydration. 23. The method of claim 20, wherein the at least one low measurement frequency comprise multiple measurement frequencies. 24. The method of claim 17, wherein the hydration signal further comprises a tissue reactance measurement. 25. The method of claim 24, further comprising determining a quality of the skin-electrode coupling from the tissue reactance measurement. 26. The method of claim 17 further comprising determining the quality of the skin-electrode coupling, and wherein determining the quality of the skin-electrode coupling comprises at least one of determining an ECG signal-to-noise ratio, determining a tissue reactance, measuring the impedance between any two of the at least four electrodes, and measuring resistance at a second measurement frequency. 27. The method of claim 26, wherein determining the quality of the skin-electrode coupling further comprises identifying a poor skin-electrode coupling when the tissue reactance is greater than a threshold of about 10Ω. 28. The method of claim 26, wherein determining the quality of the skin-electrode coupling further comprises identifying an irregular skin-electrode coupling when the tissue resistance droop exceeds a threshold of 10% of a nominal value. 29. The method of claim 26, wherein determining the quality of the skin-electrode coupling further comprises identifying a poor skin-electrode coupling when an impedance measured between two of the at least four electrodes is greater than a threshold of 5 kΩ. 30. A method of monitoring a patient, the method comprising: adhering an adhesive patch to a skin of the patient to couple at least four electrodes to the skin of the patient to form a skin-electrode interface;measuring a hydration signal of the patient with impedance circuitry coupled to the at least four electrodes, wherein the hydration signal comprises a tissue resistance measurement and a tissue reactance measurement;determining an amount of extracellular edema using the tissue resistance measurement;detecting a low frequency droop in the tissue resistance measurement; anddetermining a quality of skin-electrode coupling using the tissue reactance measurement and without using the tissue resistance measurement; andtemporarily suspending data collection based at least in part on the fact that the low frequency droop has been detected. 31. The method of claim 30, further comprising indicating a replacement status of the adhesive patch based on the quality of the skin-electrode coupling. 32. An adherent device to monitor a patient, the device comprising: an adhesive patch to adhere to a skin of the patient;at least four electrodes mechanically coupled to the patch and capable of electrically coupling to the patient, the at least four electrodes comprising at least two force electrodes and at least two sense electrodes;impedance circuitry electrically coupled to the at least two force electrodes to force an electrical current and coupled to the at least two sense electrodes to measure a hydration signal of the patient, wherein the hydration signal comprises a tissue resistance measurement; anda processor system coupled to the impedance circuitry configured to determine an amount of extracellular edema from the hydration signal,wherein the processor system is configured to calculate and report a patient risk of an adverse cardiac event to at least one of a remote center or a physician based on the amount of extracellular edema;and wherein the processor system is configured to detect a low frequency droop in the tissue resistance measurement;and wherein the processor system is further configured to, when low frequency droop is detected, temporarily suspend data collection based at least in part on the fact that the low frequency droop has been detected. 33. A method of monitoring a patient, the method comprising: adhering an adhesive patch to a skin of the patient so as to couple at least four electrodes to the skin of the patient, the at least four electrodes comprising at least two force electrodes and at least two sense electrodes;measuring a tissue resistance of the patient with impedance circuitry electrically coupled to the at least two force electrodes and to the at least two sense electrodes, such that the force electrodes force an electrical current at a frequency less than 10 kHz between the at least two force electrodes, wherein the impedance circuitry generates a hydration signal;detecting a low frequency droop in the tissue resistance measurement;determining an amount of extracellular edema from the hydration signal; andtemporarily suspending data collection based at least in part on the fact that the low frequency droop has been detected.
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