Lubricous coatings, methods for making and using lubricous coatings, and medical device that include lubricious coatings. An example lubricous coating may include a hydrophilic polymer, a flow modifier, an acrylic monomer, a photoinitiator, and a solvent. The coating can be used to coat a medical de
Lubricous coatings, methods for making and using lubricous coatings, and medical device that include lubricious coatings. An example lubricous coating may include a hydrophilic polymer, a flow modifier, an acrylic monomer, a photoinitiator, and a solvent. The coating can be used to coat a medical device along an inner surface, an outer surface, or an intermediate surface.
대표청구항▼
1. A lubricious coating material, comprising: a hydrophilic polymer;a binder substantially insoluble in water, wherein the binder swells in the presence of water;a flow modifier;an acrylic monomer, wherein upon polymerization the acrylic monomer forms an interpenetrating network;a photoinitiator; an
1. A lubricious coating material, comprising: a hydrophilic polymer;a binder substantially insoluble in water, wherein the binder swells in the presence of water;a flow modifier;an acrylic monomer, wherein upon polymerization the acrylic monomer forms an interpenetrating network;a photoinitiator; anda solvent. 2. The coating material of claim 1, wherein the hydrophilic polymer includes polyethylene oxide. 3. The coating material of claim 1, wherein the binder includes acrylic acid-styrene copolymer. 4. The coating material of claim 1, where the binder is soluble in isopropyl alcohol. 5. The coating material of claim 1, wherein the acrylic monomer includes ethoxylated trimethylol propane triacrylate esters. 6. The coating material of claim 1, wherein the photoinitator includes 2-methyl-1-[4-(methylthio)phenyl]-2-(4-morpholinyl)-1-propanone. 7. The coating material of claim 1, wherein the solvent includes water. 8. The coating material of claim 1, wherein the solvent includes an organic solvent. 9. The coating material of claim 8, wherein the solvent includes isopropyl alcohol. 10. The coating material of claim 9, wherein the solvent further includes water. 11. The coating material of claim 1, further comprising silane. 12. The coating material of claim 1, further comprising aziridine. 13. A lubricious coating material, comprising: polyethylene oxide;a flow modifier;a binder substantially insoluble in water, wherein the binder swells in the presence of water;an acrylic monomer, wherein upon polymerization the acrylic monomer forms an interpenetrating network;a photoinitiator; andisopropyl alcohol;wherein the interpenetrating network forms a web that holds the lubricious coating material on a substrate. 14. The coating material of claim 13, wherein the coating material includes about 1-15 wt-% polyethylene oxide. 15. The coating material of claim 13, wherein the coating material includes about 50-99.9 wt-% isopropyl alcohol. 16. The coating material of claim 13, further comprising aziridine. 17. The coating material of claim 13, further comprising a silane. 18. A medical device, comprising: an elongate shaft;a lubricious coating disposed on the shaft; andwherein the lubricious coating includes a hydrophilic polymer, a silane, a flow modifier, a photoinitiator, and an acrylic monomer, and wherein the acrylic monomer is cross-linked to form an interpenetrating network. 19. The medical device of claim 18, wherein the lubricious coating is disposed along an outer surface of the shaft. 20. The medical device of claim 18, wherein the shaft defines a lumen and an inner surface along the lumen, and wherein the lubricous coating is disposed along the inner surface. 21. The medical device of claim 18, wherein the lubricious coating is disposed along an intermediate surface of the shaft. 22. A lubricious coating material, comprising: a hydrophilic polymer;a silane;a flow modifier;a photoinitiator;aziridine; andan acrylic monomer that is cross-linked to form an interpenetrating network. 23. A method for forming a lubricious coating material, the method comprising: mixing together a hydrophilic polymer, a silane, a flow modifier, a photoinitiator, aziridine, and an acrylic monomer; andcross-linking the acrylic monomer to form an interpenetrating network. 24. The method of claim 23, wherein cross-linking the acrylic monomer to form an interpenetrating network includes exposing the acrylic monomer to UV light.
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