초록

Biocompatible sensors configured for implantation include a first body in communication with a plurality of remote sensor bodies to detect physiological parameters in vivo.

대표청구항 ▼

1. An implantable biocompatible device, comprising: a primary sensor body holding operating electronics; anda plurality of arms extending outwardly from the primary sensor body, each of said arms having distal portions containing at least one sensor thereon and having at least one signal path extend

1. An implantable biocompatible device, comprising: a primary sensor body holding operating electronics; anda plurality of arms extending outwardly from the primary sensor body, each of said arms having distal portions containing at least one sensor thereon and having at least one signal path extending between said operating electronics in said primary body portion to said sensors,wherein at least one of the sensors comprises a MOSFET radiation sensor that is passive during exposure to ionizing radiation and is configured to be inductively powered after a radiation exposure to wirelessly transmit data corresponding to a dose of radiation delivered internally at a target tumor treatment site while remaining implanted. 2. The device of claim 1, wherein at least one of said arms includes a plurality of sensor elements. 3. The device of claim 1, wherein said arms are configured with an anchor portion adapted to positionally attach to a desired solid tissue body portion thereby allowing attachment to a surface or at a depth into the tumor. 4. The device of claim 1, wherein said sensor elements include at least one temperature sensor element. 5. The device of claim 1, wherein the primary body comprises a transmitter coil and associated electronic components configured for wireless transmittal of the sensor data to a spatially remote receiver, wherein the primary body is inductively powered. 6. The device of claim 1, wherein said primary sensor body and arms are sized and configured to be chronically implanted in a subject. 7. The device of claim 1 in combination with an external reader in wireless communication with the primary sensor body. 8. The device of claim 1, wherein a plurality of the discrete sensors comprise at least one MOSFET radiation sensor element, the MOSFET radiation sensor element being passive during exposure to ionizing radiation and inductively powered after a radiation exposure to wirelessly transmit data via the primary sensor body to an external reader while remaining implanted, the data corresponding to a dose of radiation that was delivered internally at a target tumor site. 9. The device of claim 1, wherein at least one of the sensors is configured to detect temperature and/or oxygen.