IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0568527
(2009-09-28)
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등록번호 |
US-8383092
(2013-02-26)
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발명자
/ 주소 |
- Lee, Bruce P.
- Vollenweider, Laura
- Murphy, John L.
- Xu, Fangmin
- Dalsin, Jeffrey L.
- Virosco, Jeanne
- Lew, William
- White, Jed
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출원인 / 주소 |
- KNC NER Acquisition Sub, Inc.
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인용정보 |
피인용 횟수 :
5 인용 특허 :
94 |
초록
▼
The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for exam
The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons.
대표청구항
▼
1. A bioadhesive construct, comprising: a support; anda coating comprising a multihydroxyphenyl (DHPD) functionalized polymer (DHPp) wherein the functionalized DHPp comprises the formula: CA-[Z-PA-(L)a-(DHPD)b]n whereinCA is a central atom that is carbon;each Z, independently, is a C1 to a C6 linear
1. A bioadhesive construct, comprising: a support; anda coating comprising a multihydroxyphenyl (DHPD) functionalized polymer (DHPp) wherein the functionalized DHPp comprises the formula: CA-[Z-PA-(L)a-(DHPD)b]n whereinCA is a central atom that is carbon;each Z, independently, is a C1 to a C6 linear or branched, substituted or unsubstituted alkyl group or a bond;each PA, independently, is a substantially poly(ethylene oxide) polyether;each L, independently, is a succinamic acid linker wherein an ester group links said succinamic acid linker to said PA and wherein an amide group links said succinamic acid linker to said DHPD;each DHPD, independently is a multihydroxy phenyl;“a” has a value of a value of 1;“b” has a value of 1; and“n” has a value of 4. 2. The bioadhesive construct of claim 1, further comprising an oxidant. 3. The bioadhesive construct of claim 1, wherein the oxidant is formulated with the coating. 4. The bioadhesive of claim 2, wherein the oxidant is applied to the coating. 5. The bioadhesive construct of claim 1, wherein the support is a film, a mesh, a membrane, or a prosthetic. 6. The bioadhesive construct of claim 4, wherein the support is a film, a mesh, a membrane, or a prosthetic. 7. The bioahesive construct of claim 1, wherein the construct is hydrated. 8. The bioadhesive construct of claim 4, wherein the construct is hydrated.
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