[특허]Neurostimulator involving stimulation strategies and process for using it

Neurostimulator involving stimulation strategies and process for using it 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61N-001/00 A61B-005/04
출원번호	US-0106747 (2011-05-12)
등록번호	US-8412333 (2013-04-02)
발명자 / 주소	Pless, Benjamin D
출원인 / 주소	NeuroPace, Inc.
인용정보	피인용 횟수 : 0 인용 특허 : 102

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This is a neurostimulator that is configured to treat epilepsy and other neurological disorders using certain stimulation strategies, particularly changing various pulse parameters, during the imposition of a burst of those pulses. The invention includes the processes embodying those stimulation str

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1. A method for treating an abnormal neurological condition comprising: detecting electrical activity of brain tissue wherein the detected electrical activity is characterized by at least one detected parameter;applying a plurality of bursts of electrical stimulation to the brain tissue, wherein each burst of the plurality of bursts comprises a determined number of electrical pulses being characterizable by a plurality of burst parameters; andvarying at least one of the burst parameters during at least a portion of the time the plurality of bursts of electrical stimulation is applied to vary the bursts so that the burst parameters of at least one burst of the plurality of bursts are different from the burst parameters of at least one other burst of the plurality of bursts, wherein the varying is based on a timing of the at least one detected parameter. 2. The method of claim 1 further including varying at least one of the burst parameters based on the timing of the at least one detected parameter relative to a timing of an application of the at least one burst of the plurality of bursts. 3. The method of claim 1 wherein the at least one detected parameter is a pulse-to-pulse interval and the method further includes varying at least one of the burst parameters of the plurality of burst parameters based on the detected pulse-to-pulse interval. 4. A method for treating an abnormal neurological condition comprising: detecting electrical activity of brain tissue wherein the detected electrical activity is characterized by at least one detected parameter;applying a plurality of bursts of electrical stimulation to the brain tissue, wherein each burst of the plurality of bursts comprises a determined number of electrical pulses being characterizable by a plurality of burst parameters and at least one burst of the plurality of bursts is applied at a time that is synchronized to a time at which the at least one detected parameter is detected; andvarying at least one of the burst parameters during at least a portion of the time the plurality of burst parameters of electrical stimulation is applied to vary the bursts so that the burst parameters of at least one burst of the plurality of bursts are different from the burst parameters of at least one other burst of the plurality of bursts. 5. A method for treating an abnormal neurological condition comprising: detecting a rate of electrical activity in signals sensed from brain tissue;identifying an interval corresponding to the detected rate;applying a plurality of bursts of electrical stimulation to the brain tissue, wherein each burst of the plurality of bursts comprises a determined number of electrical pulses being characterizable by a plurality of burst parameters and at least one burst of the plurality of bursts is applied based on detection of the interval; andvarying at least one of the burst parameters during at least a portion of a time the plurality of bursts of electrical stimulation is applied to vary the bursts so that the burst parameters of at least one burst of the plurality of bursts are different from the burst parameters of at least one other burst of the plurality of bursts.

이 특허에 인용된 특허 (102)

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Pless,Benjamin D., Electrical stimulation strategies to reduce the incidence of seizures.
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Abrams Richard (Chicago IL) Swartz Conrad M. (Lake Forest IL), Electroconvulsive therapy apparatus and method for automatic monitoring of patient seizures.
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Baker ; Jr. Ross G. (Houston TX), Electrode assembly for nerve stimulation.
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David R. Fischell ; Stephen T. Archer ; Robert E. Fischell ; Adrian R. M. Upton CA, Implantable device for patient communication.
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