IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0575671
(2005-09-28)
|
등록번호 |
US-8413654
(2013-04-09)
|
우선권정보 |
AU-2004905584 (2004-09-28) |
국제출원번호 |
PCT/AU2005/001493
(2005-09-28)
|
§371/§102 date |
20080926
(20080926)
|
국제공개번호 |
WO2006/034549
(2006-04-06)
|
발명자
/ 주소 |
|
출원인 / 주소 |
|
대리인 / 주소 |
Lerner, David, Littenberg, Krumholz & Mentlik, LLP
|
인용정보 |
피인용 횟수 :
2 인용 특허 :
9 |
초록
A CPAP apparatus has a variable rise time (iii) from a base level of positive air pressure during expiration (EPAP) to a higher level during inspiration (IPAP). The rise time is adjusted in order to reduce obstruction, resistance or instability in the upper airway.
대표청구항
▼
1. A method for operating a CPAP apparatus having a flow generator, a patient interface, an air delivery conduit for delivering air from the flow generator to the patient interface, and a control mechanism that causes air to be delivered through the air delivery conduit at desired pressures at the p
1. A method for operating a CPAP apparatus having a flow generator, a patient interface, an air delivery conduit for delivering air from the flow generator to the patient interface, and a control mechanism that causes air to be delivered through the air delivery conduit at desired pressures at the patient interface, the method comprising the steps of: (i) controlling the flow generator to reduce the air flow through the delivery conduit to the patient interface to deliver a lower base level of positive air pressure (“EPAP”) in the patient interface during an expiratory portion of the patient's respiratory cycle;(ii) controlling the flow generator to increase air flow through the delivery conduit to the patient interface during inhalation so as to maintain the pressure in the patient interface at a higher level (“IPAP”) suitable for inhalation, wherein the time for the flow generator to increase the pressure from EPAP to IPAP is a variable rise time; and(iii) monitoring the shape of the inspiratory portion of the respiratory airflow and increasing the rise time upon detection of a shape indicative of the presence of upper airway obstruction, resistance or instability. 2. The method for operating a CPAP apparatus of claim 1, wherein the shape indicative of the presence of upper airway obstruction, resistance or instability is a flattened shape. 3. The method for operating a CPAP apparatus of claim 2, wherein the rise time is increased to a value that resolves the flattening. 4. The method for operating a CPAP apparatus of claim 1, wherein the patient receives a supply of air at about 13.5 cm H2O during inspiration and approximately 10 cm H2O during exhalation. 5. The method for operating a CPAP apparatus of claim 1, wherein the rise time is increased from approximately 150 ms to 500 ms. 6. The method for operating a CPAP apparatus of claim 1, further comprising the step of reducing the rise time when the patient's airway becomes stable. 7. The method for operating a CPAP apparatus of claim 1, further comprising the steps of (iv) discontinuing the increased rise time when the patient's airway becomes stable and reverting to a previous faster rise time. 8. The method for operating a CPAP apparatus of claim 1, further comprising the step of logging the changes in rise time performed by the device and providing a measure of the number of occurrences and duration of airway instability incident experienced. 9. A method for reducing or eliminating upper airway obstruction, resistance or instability by use of a CPAP apparatus having a variable rise time from EPAP to IPAP comprising the step of increasing the rise time of the apparatus in response to an indication of an upper airway obstruction, resistance or instability. 10. The method of claim 9 for use in a CPAP apparatus having a flow generator, a patient interface, an air delivery conduit for delivering air from the flow generator to the patient interface, and a control mechanism that causes air to be delivered through the air delivery conduit at desired pressures at the patient interface, the method comprising the steps of: (i) controlling the flow generator to reduce the air flow through the delivery conduit to the patient interface to deliver a lower base level of positive air pressure (“EPAP”) in the patient interface during an expiratory portion of the patient's respiratory cycle;(ii) controlling the flow generator to increase air flow through the delivery conduit to the patient interface during inhalation so as to maintain the pressure in the patient interface at a higher level (“IPAP”) suitable for inhalation, wherein the time for the flow generator to increase the pressure from EPAP to IPAP is a variable rise time; and(iii) monitoring patient effort for detection of the presence of upper airway obstruction, resistance or instability and upon such detection increasing ventilator rise-time. 11. The method of claim 10, wherein patient effort is monitored by an apparatus selected from the group consisting of pressure and flow sensors, bands around the chest and/or abdomen of the patient and suprasternal notch effort sensors. 12. The method of claim 10, wherein the patient receives a supply of air at about 13.5 cm H2O during inspiration and approximately 10 cm H2O during exhalation. 13. The method of claim 10, wherein the rise time is increased from approximately 150 ms to 500 ms. 14. The method of claim 10, wherein the rise time is increased to a value that resolves the upper airway obstruction, resistance or instability. 15. The method of claim 10, further comprising the step of reducing the rise time when the patient's airway becomes stable. 16. The method of claim 10, further comprising the steps of (iv) discontinuing the increased rise time when the patient's airway becomes stable and reverting to a previous faster rise time. 17. The method of claim 10, further comprising the step of logging the changes in rise time performed by the device and providing a measure of the number of occurrences and duration of airway instability incident experienced. 18. A CPAP apparatus having a flow generator, a patient interface, an air delivery conduit for delivering air from the flow generator to the patient interface, and a control mechanism that causes air to be delivered through the air delivery conduit at desired pressures at the patient interface, said apparatus having: (i) a lower base level of positive air pressure (“EPAP”) in the patient interface during an expiratory portion of the patient's respiratory cycle;(ii) a higher level (“IPAP”) suitable for inhalation, wherein the time for the flow generator to increase the pressure from EPAP to IPAP is a variable rise time; and(iii) a controller for monitoring the shape of the inspiratory portion of the respiratory airflow and, increasing the rise time upon detection of a shape indicative of the presence of upper airway obstruction, resistance or instability. 19. The CPAP apparatus of claim 18, wherein the shape indicative of the presence of upper airway obstruction, resistance or instability is a flattened shape. 20. The CPAP apparatus of claim 19, wherein the rise time is increased to a value that resolves the flattening. 21. The CPAP apparatus of claim 18, wherein the patient receives a supply of air at about 13.5 cm H2O during inspiration and approximately 10 cm H2O during exhalation. 22. The CPAP apparatus of claim 18, wherein the rise time is increased from approximately 150 ms to 500 ms. 23. The CPAP apparatus of claim 18, further comprising the step of reducing the rise time when the patient's airway becomes stable. 24. The CPAP apparatus of claim 18, wherein said controller discontinues the increased rise time when the patient's airway becomes stable and reverts to a previous faster rise time. 25. A CPAP apparatus having a flow generator, a patient interface, an air delivery conduit for delivering air from the flow generator to the patient interface, and a control mechanism that causes air to be delivered through the air delivery conduit at desired pressures at the patient interface, said apparatus having: (i) a lower base level of positive air pressure (“EPAP”) in the patient interface during an expiratory portion of the patient's respiratory cycle;(ii) a higher level positive air pressure (“IPAP”) suitable for inhalation, wherein the time for the flow generator to increase the pressure from EPAP to IPAP is a variable rise time; and(iii) a controller for monitoring patient effort for detection of the presence of upper airway obstruction, resistance or instability and upon such detection increasing ventilator rise time. 26. Apparatus for treating sleep disordered breathing comprising: a controllable source of breathable gas at positive pressure;an air delivery conduit and patient interface adapted to provide gas from said source to the entrance of a patient's airways;a flow transducer adapted to provide a flow signal indicative of the respiratory flow of air to the patient's airways;a controller programmed to determine the beginning of an inhalation portion of a patient's respiratory cycle from said flow signal and thereupon to increase the pressure of breathable gas from said source from an exhalatory pressure to an inhalatory pressure within an adjustable risetime; andwherein said controller is further adapted to determine an index of upper airway obstruction from said flow signal and increase said risetime when the index indicates the presence of upper airway obstruction. 27. Apparatus as claimed in claim 26 wherein said controller adjusts said risetime as a function of said index. 28. Apparatus as claimed in claim 26 wherein said index is a shape index. 29. Apparatus as claimed in claim 28 wherein said index is a flattening index. 30. Apparatus as claimed in claim 29 wherein risetime is increased when the flattening index has a value indicative of flattening occurring. 31. Apparatus as claimed in claim 26 wherein said index is a snore index. 32. Apparatus as claimed in claim 26 wherein said index is an hypopnea index. 33. A method for operating a CPAP apparatus having a flow generator, a patient interface, an air delivery conduit for delivering air from the flow generator to the patient interface, and a control mechanism that causes air to be delivered through the air delivery conduit at desired pressures at the patient interface, the method comprising the steps of: (i) controlling the flow generator to reduce the air flow through the delivery conduit to the patient interface to deliver a lower base level of positive air pressure (“EPAP”) in the patient interface during an expiratory portion of the patient's respiratory cycle;(ii) controlling the flow generator to increase air flow through the delivery conduit to the patient interface during inhalation so as to maintain the pressure in the patient interface at a higher level (“IPAP”) suitable for inhalation, wherein the time for the flow generator to increase the pressure from EPAP to IPAP is a variable rise time; and(iii) increasing the rise time upon detection of the presence of upper airway obstruction, resistance or instability. 34. A CPAP apparatus having a flow generator, a patient interface, an air delivery conduit for delivering air from the flow generator to the patient interface, and a control mechanism that causes air to be delivered through the air delivery conduit at desired pressures at the patient interface, said apparatus having: (i) a lower base level of positive air pressure (“EPAP”) in the patient interface during an expiratory portion of the patient's respiratory cycle;(ii) a higher level positive air pressure (“IPAP”) suitable for inhalation, wherein the time for the flow generator to increase the pressure from EPAP to IPAP is a variable rise time; and(iii) a controller for increasing the rise time upon detection of the presence of upper airway obstruction, resistance or instability.
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