An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye. In some embodiments the implant has a body extending in a curved volume whose longitudinal axis forms an arc of a circle, and a plurality of open areas and strut areas formed in the body, the open areas
An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye. In some embodiments the implant has a body extending in a curved volume whose longitudinal axis forms an arc of a circle, and a plurality of open areas and strut areas formed in the body, the open areas extending over more than 50% of a surface defining the curved volume, the strut areas surrounding the open areas, the body having a diameter of between 0.005 inches and 0.04 inches. The invention also provides a method of treating glaucoma including the steps of supporting tissue forming Schlemm's canal in an eye with an implant extending at least partially in the canal along an axial length within the canal; and contacting with the implant less than 50% of the tissue forming the canal along the axial length.
대표청구항▼
1. A method of treating glaucoma comprising: inserting an ocular implant into a human eye, the ocular implant comprising an inlet portion at a proximal end, the inlet portion comprising an opening, a Schlemm's canal portion disposed distal to the inlet portion, the Schlemm's canal portion having an
1. A method of treating glaucoma comprising: inserting an ocular implant into a human eye, the ocular implant comprising an inlet portion at a proximal end, the inlet portion comprising an opening, a Schlemm's canal portion disposed distal to the inlet portion, the Schlemm's canal portion having an elongate opening extending longitudinally along the implant and a central channel extending through the inlet portion and the Schlemm's canal portion, the central channel being in fluid communication with the inlet opening and the elongate opening;advancing the Schlemm's canal portion of the implant into Schlemm's canal, so that the Schlemm's canal portion tracks Schlemm's canal as it is advanced;orienting the elongate opening toward collector channels in communication with Schlemm's canal; anddisposing the inlet portion opening in an anterior chamber of the eye. 2. The method of claim 1 wherein the inlet portion opening comprises an open channel extending longitudinally along the inlet portion, the step of disposing the inlet portion comprising disposing the inlet portion in the anterior chamber so that the open channel faces away from the meshwork. 3. The method of claim 1 wherein the step of disposing the Schlemm's canal portion of the inlet in Schlemm's canal comprises extending the Schlemm's canal portion within Schlemm's canal 60°-180° around the pupil of the eye. 4. A method of treating glaucoma comprising: inserting an ocular implant into a human eye, the ocular implant comprising a central channel;disposing an inlet portion of the implant in an anterior chamber of the eye, the inlet portion comprising an opening in fluid communication with the central channel;disposing a Schlemm's canal portion of the inlet in Schlemm's canal, the Schlemm's canal portion having an elongate opening extending longitudinally along the implant in fluid communication with the central channel; andorienting the elongate opening toward collector channels in communication with Schlemm's canal;wherein the Schlemm's canal portion of the implant comprises a first spine extending longitudinally along the central channel, a second spine extending longitudinally along the central channel, the second spine being disposed distal to the first spine, a first frame extending longitudinally along the central channel, the first frame being disposed distal to the first spine and proximal to the second spine, the first frame having a circumferential extent around the central channel greater than a circumferential extent of the first spine and a circumferential extent of the second spine, and a second frame extending longitudinally along the central channel, the second frame being disposed distal to the second spine, the second frame having a circumferential extent around the central channel greater than the circumferential extent of the first spine and the circumferential extent of the second spine, the elongate opening extending longitudinally along a portion of a curved volume bordered by the spines and the frames the method further comprising orienting the spines away from the collector channels. 5. The method of claim 4 wherein the method further comprises orienting the spines against the meshwork. 6. The method of claim 4 wherein the first and second frames each comprise an opening circumferentially offset from the elongate opening and in fluid communication with the central channel, the method further comprising orienting the first and second frame openings against the meshwork. 7. The method of claim 1 wherein the ocular implant is curved and the inlet portion extends along the curve. 8. The method of claim 1 wherein the ocular implant is curved, the elongate opening facing radially outward from the implant. 9. The method of claim 8 wherein the ocular implant further comprises a plurality of openings on a smaller radius side of the Schlemm's canal portion of the implant than the elongate opening. 10. The method of claim 9 further comprising orienting the plurality of openings toward trabecular meshwork. 11. The method of claim 1 further comprising supporting the trabecular meshwork with the inlet portion. 12. The method of claim 1 wherein the elongate opening extends along all of the Schlemm's canal portion of the implant, the advancing step comprising advancing all of the Schlemm's canal portion of the implant into and along Schlemm's canal. 13. A method of treating glaucoma comprising: inserting a curved ocular implant into a human eye, the ocular implant comprising an inlet portion at a proximal end, wherein the ocular implant terminates with the inlet portion, the inlet portion comprising an opening, a Schlemm's canal portion disposed distal to the inlet portion, the Schlemm's canal portion having an elongate opening extending longitudinally along the implant facing radially outward and a central channel extending through the inlet portion and the Schlemm's canal portion, the central channel being in fluid communication with the inlet opening and the elongate opening;advancing the Schlemm's canal portion of the implant into Schlemm's canal;orienting the elongate opening toward collector channels in communication with Schlemm's canal;disposing the inlet portion opening in an anterior chamber of the eye; andsupporting trabecular meshwork with the inlet portion. 14. The method of claim 13 wherein the inlet portion extends along the curve of the implant. 15. The method of claim 13 wherein the ocular implant further comprises a plurality of openings on a smaller radius side of the Schlemm's canal portion of the implant than the elongate opening, the method further comprising orienting the plurality of openings toward trabecular meshwork. 16. The method of claim 13 wherein the elongate opening extends along all of the Schlemm's canal portion of the implant, the advancing step comprising advancing all of the Schlemm's canal portion of the implant into and along Schlemm's canal. 17. The method of claim 13 wherein the inlet portion opening comprises an open channel extending longitudinally along the inlet portion, the step of disposing the inlet portion comprising disposing the inlet portion in the anterior chamber so that the open channel faces away from the meshwork. 18. The method of claim 13 wherein the step of disposing the Schlemm's canal portion of the inlet in Schlemm's canal comprises advancing the Schlemm's canal portion within Schlemm's canal 60°-180° around the pupil of the eye.
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이 특허에 인용된 특허 (82)
Suson John (362F Willow Grove Dr. Pewaukee WI 53072), Adjustable flow rate glaucoma shunt and method of using same.
Thomas Neuhann DE, Device for improving in a targeted manner and/or permanently ensuring the ability of the aqueous humor to pass through the trabecular meshwork.
Klemm Kurt R. (Santa Clara CA) Lau Lilip (Sunnyvale CA) Hartigan William M. (Fremont CA) Khosravi Farhad (Boston MA) Williams Michael S. (Chapel Hill NC) Beitelia Rainier (San Jose CA), Stent delivery system.
Ritch Robert (455 E. 57th St. New York NY 10022) Klein Edward E. (12 Haights Cross Rd. Chappaqua NY 10514), Transscleral drainage implant device for the treatment of glaucoma.
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