최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0267494 (2008-11-07) |
등록번호 | US-8425417 (2013-04-23) |
발명자 / 주소 |
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출원인 / 주소 |
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인용정보 | 피인용 횟수 : 5 인용 특허 : 467 |
Systems and methods of use for continuous analyte measurement of a host's vascular system and the simultaneous control of a flow control device are provided. In some embodiments, an integrated system includes a vascular access device, a continuous analyte sensor, system electronics and an electronic
Systems and methods of use for continuous analyte measurement of a host's vascular system and the simultaneous control of a flow control device are provided. In some embodiments, an integrated system includes a vascular access device, a continuous analyte sensor, system electronics and an electronic cable for communication with a third-party infusion device, the system being configured for insertion into fluid communication with a host's circulatory system.
1. A system for analyte detection in and fluid infusion into a host, comprising: an analyte sensor configured and arranged to generate sensor data associated with an analyte;a fluid coupler configured to connect an IV equipment with a vascular access device configured for fluid communication with a
1. A system for analyte detection in and fluid infusion into a host, comprising: an analyte sensor configured and arranged to generate sensor data associated with an analyte;a fluid coupler configured to connect an IV equipment with a vascular access device configured for fluid communication with a circulatory system of the host; andsystem electronics operably connected to the analyte sensor and configured to process the sensor data, wherein the system electronics comprise: a processor module configured to control a flow profile of a flow control device, wherein the flow profile is configured to intermittently control flow of a fluid through the vascular access device into the circulatory system of the host and to intermittently control a flow of a sample from the circulatory system of the host into the vascular access device when the vascular access device is in fluid communication with the circulatory system of the host and operably connected to the flow control device;a data storage memory configured to store the sensor data associated with the analyte of the host; andan output module configured and arranged to operably connect with the flow control device so as to enable the processor module to control the flow profile of the flow control device anda cable configured to provide a wired connection between the system electronics and the analyte sensor, wherein the cable comprises the data storage memory wherein the system electronics are configured to be powered at least in part by a flow control device. 2. The system of claim 1, wherein the cable is configured to operably connect with a flow control device. 3. The system of claim 2, wherein at least a portion of the system electronics is physically connected to the cable such that the at least a portion of the system electronics is located within a distance of about 8 feet or less of the analyte sensor. 4. The system of claim 1, wherein the system electronics are located on the electrical cable. 5. The system of claim 4, wherein the system electronics are located within a distance of about 3 feet or less of the analyte sensor. 6. The system of claim 1, wherein the system electronics are non-releasably connected with the analyte sensor. 7. The system of claim 1, wherein the system electronics are releasably connected to the analyte sensor. 8. The system of claim 1, wherein the output module is configured and arranged for wireless communication with a flow control device. 9. The system of claim 1, wherein the processor module comprises a fail-safe module. 10. The system of claim 1, wherein the system electronics are configured to process the sensor data to obtain one or more sensor analyte values, and wherein the flow profile is determined based at least in part on the one or more sensor analyte values. 11. The system of claim 1, further comprising a source of a solution comprising a medicament. 12. The system of claim 11, wherein the flow profile is configured to intermittently control flow of the solution comprising the medicament through the vascular access device into the circulatory system of the host. 13. The system of claim 1, wherein the vascular access device comprises a catheter, wherein the analyte sensor comprises an electrode, and wherein the electrode is located within or on the catheter. 14. The system of claim 1, wherein the fluid coupler comprises a first end configured for fluid communication with a catheter configured for implantation in a host's circulatory system and a second end configured for fluid communication with tubing associated with a flow control device. 15. The system of claim 1, wherein at least a portion of the analyte sensor is located within the vascular access device. 16. The system of claim 1, wherein the analyte sensor is located within a distance of about 40 mm or less of an opening in the vascular access device through which a biological sample from the circulatory system of the host is obtained when the vascular access device is in fluid communication with the circulatory system of the host. 17. The system of claim 1, wherein the analyte sensor is located such that the analyte sensor is bathed in a biological sample from the circulatory system of the host when a volume of about 300 μL or less of the biological sample is drawn back into the vascular access device when the vascular access device is in fluid communication with the circulatory system of the host. 18. The system of claim 1, wherein the analyte sensor is configured to continuously measure glucose in a host. 19. The system of claim 1, wherein the analyte sensor is configured to measure a signal associated with at least one analyte selected from the group consisting of albumin, alkaline phosphatase, alanine transaminase, aspartate aminotransferase, bilirubin, blood urea nitrogen, calcium, CO2 chloride, creatinine, glucose, gamma-glutamyl transpeptidase, hematocrit, lactate, lactate dehydrogenase, magnesium, oxygen, pH, phosphorus, potassium, sodium, total protein, uric acid, a metabolic marker, and a drug. 20. The system of claim 1, further comprising a flow control device configured for fluid communication with the vascular access device and configured to intermittently infuse a fluid and draw back a biological sample of the circulatory system responsive to the flow profile. 21. The system of claim 20, wherein the flow control device comprises a pump. 22. The system of claim 21, wherein the pump comprises a bi-directional pump. 23. The system of claim 21, wherein the pump comprises a peristaltic pump. 24. A system for analyte detection in and fluid infusion into a host, comprising: an analyte sensor configured and arranged to generate sensor data associated with an analyte;a fluid coupler configured to connect an IV equipment with a vascular access device configured for fluid communication with a circulatory system of the host; andsystem electronics operably connected to the analyte sensor and configured to process the sensor data, wherein the system electronics comprise: a processor module configured to control a flow profile of a flow control device, wherein the flow profile is configured to intermittently control flow of a fluid through the vascular access device into the circulatory system of the host and to intermittently control a flow of a sample from the circulatory system of the host into the vascular access device when the vascular access device is in fluid communication with the circulatory system of the host and operably connected to the flow control device;a data storage memory configured to store the sensor data associated with the analyte of the host; andan output module configured and arranged to operably connect with the flow control device so as to enable the processor module to control the flow profile of the flow control device; anda cable configured to provide a wired connection between the system electronics and the analyte sensor, wherein the cable comprises the data storage memory,wherein the system electronics are actuated upon engagement of the system electronics with a flow control device.
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