IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0154848
(2011-06-07)
|
등록번호 |
US-8431086
(2013-04-30)
|
우선권정보 |
WO-PCT/US2007/074003 (2007-07-20) |
발명자
/ 주소 |
- Lurvey, Kent L.
- Sternberg, Shmuel
- Krongauz, Vadim V.
- Yeh, Rosa H.
- Pauley, Robin G.
- Cawthon, Dustin C.
- Hai, Ton That
- Woo, Lecon L.
- Khanna, Ashok K.
- Lal, Birendra K.
- Ling, Michael Tung-Kiung
- Hoerle, William S.
- Sandford, Craig L.
- Nordhaus, Mark A.
- Savitski, Alexander
- Kirichkow, Nicklaus J.
- Suh, Kenneth Glen
- Krishnamoorthy, Sivaramakrishnan
- Yang, Hsinjin E.
- Clarke, Robert A.
|
출원인 / 주소 |
- Baxter International Inc.
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
6 인용 특허 :
63 |
초록
▼
A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been
A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.
대표청구항
▼
1. A medical fluid access device comprising: a housing and a valve member defining a fluid access site for introduction and withdrawal of fluids; anda polymeric porous indicator including a color changing dye,wherein the polymeric porous indicator is disposed at the access site, wherein upon exposur
1. A medical fluid access device comprising: a housing and a valve member defining a fluid access site for introduction and withdrawal of fluids; anda polymeric porous indicator including a color changing dye,wherein the polymeric porous indicator is disposed at the access site, wherein upon exposure to an antiseptic solution the color changing dye changes from a first color to a second color, and wherein the dye resumes the first color after a period of time. 2. The access device of claim 1, wherein the color changing dye is a solvatochromic dye. 3. The access device of claim 2, wherein the color changing dye is a merocyanine dye or a salt or derivative thereof, or Reichardt's dye or a salt or derivative thereof. 4. The access device of claim 1, wherein the color changing dye comprises a compound having the structure: and derivatives and salts thereof, and wherein R1 is acryloyl, methacryloyl, or hydrogen, R2 is C4 to C10 alkyl, R3 is ethene, R4 and R6 are bromide, chloride, fluoride, iodide, and mixtures thereof, R5 is one of hydrogen or O−, and R7 is the other of hydrogen and O−. 5. The access device of claim 4, wherein if R1 is acryloyl, the derivatives comprise ammonium hydroxide, alkali and alkaline earth salts, and mixtures thereof, and if R1 is hydrogen, the derivatives comprise a hydrobromide, hydrochloride, hydrofluoride, phosphate, sulfate, and mixtures thereof. 6. The access device of claim 4, wherein R1 is hydrogen, R2 is n-hexyl, R4 and R6 are chloride, R5 is hydrogen, and R7 is O−. 7. The access device of claim 1, wherein the indicator is alcohol permeable and the polymer from which the indicator is made has an index of refraction from about 1.25 to about 1.6. 8. The access device of claim 1, wherein the indicator further comprises a solvatochromic dye or a salt or a derivative thereof in an amount from about 0.1% to about 0.5% of the weight of the material. 9. The access device of claim 1, wherein the polymer is at least one of acrylic, COC, nylon, methacrylic, elastomer, polycarbonate, polyurethane, epoxy, polyester, and vinylester. 10. The access device of claim 1, wherein the porous polymeric indicator comprises a membrane made from a polymer having an index of refraction from about 1.25 to about 1.6, and further comprising a coating containing the color changing dye. 11. The access device of claim 1, wherein the color changing dye is chemically bonded to the access site.
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