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특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Stabilised prostaglandin composition

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61K-009/14   
미국특허분류(USC) 424/486;
출원번호 US-0429678 (2012-03-26)
등록번호 US-8460707 (2013-06-11)
우선권정보 GB-0417401.7 (2004-08-05)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Fish & Richardson P.C.
인용정보 피인용 횟수 : 1  인용 특허 : 260
초록

A pharmaceutical delivery device, such as a suppository or pessary, comprises a synthetic prostaglandin PGE1 analogue (e.g. misoprostol) in a solid polyurethane hydrogel. The polyurethane is either linear or cross-linked.

대표
청구항
▼

1. A method for the stabilization of a PGE1 analogue, comprising: drying a pharmaceutical delivery device comprising a polyurethane hydrogel and a PGE1 analogue disposed in the hydrogel, thereby achieving a water content of the hydrogel in the range of 0.1% to 0.2% by weight. 2. A method according to claim 1, further comprising storing the delivery device at a temperature above 4° C. after drying. 3. A method according to claim 2, wherein the delivery device is stored at a temperature of about 25° C. 4. A method according to claim 3 wherein the polyureth...

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