IPC분류정보
국가/구분 |
United States(US) Patent
등록
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국제특허분류(IPC7판) |
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출원번호 |
US-0469127
(2009-05-20)
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등록번호 |
US-8475370
(2013-07-02)
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발명자
/ 주소 |
- McCombie, Devin
- Dhillon, Marshal
- Banet, Matt
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 |
피인용 횟수 :
32 인용 특허 :
138 |
초록
▼
The invention provides a system and method for measuring vital signs (e.g. SYS, DIA, SpO2, heart rate, and respiratory rate) and motion (e.g. activity level, posture, degree of motion, and arm height) from a patient. The system features: (i) first and second sensors configured to independently gener
The invention provides a system and method for measuring vital signs (e.g. SYS, DIA, SpO2, heart rate, and respiratory rate) and motion (e.g. activity level, posture, degree of motion, and arm height) from a patient. The system features: (i) first and second sensors configured to independently generate time-dependent waveforms indicative of one or more contractile properties of the patient's heart; and (ii) at least three motion-detecting sensors positioned on the forearm, upper arm, and a body location other than the forearm or upper arm of the patient. Each motion-detecting sensor generates at least one time-dependent motion waveform indicative of motion of the location on the patient's body to which it is affixed. A processing component, typically worn on the patient's body and featuring a microprocessor, receives the time-dependent waveforms generated by the different sensors and processes them to determine: (i) a pulse transit time calculated using a time difference between features in two separate time-dependent waveforms, (ii) a blood pressure value calculated from the time difference, and (iii) a motion parameter calculated from at least one motion waveform.
대표청구항
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1. A method for monitoring a patient, comprising the following steps: (a) detecting a first time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a first sensor comprising a first detector configured to be worn on the patient's body;(b) de
1. A method for monitoring a patient, comprising the following steps: (a) detecting a first time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a first sensor comprising a first detector configured to be worn on the patient's body;(b) detecting a second time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a second sensor comprising a second detector configured to be worn on the patient's body;(c) detecting sets of time-dependent motion waveforms with at least two motion-detecting sensors positioned on different locations on the patient's body, wherein each motion-detecting sensor detects a set of motion waveforms indicative of motion of the location on the patient's body to which the motion-detecting sensor is affixed;(d) processing the first and second time-dependent physiological waveforms to determine at least one vital sign from the patient;(e) analyzing at least a portion of each set of time-dependent motion waveforms, or a mathematical derivative thereof, to determine a motion parameter;(f) processing the motion parameter to determine a probability that the patient is undergoing a specific activity state; and(g) estimating the patient's activity state based on the probability,wherein step (e) further comprises analyzing a time-dependent variation of least one motion waveform, and calculating a mathematical derivative of at least one motion waveform to determine the motion parameter. 2. A method for monitoring a patient, comprising the following steps: (a) detecting a first time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a first sensor comprising a first detector configured to be worn on the patient's body;(b) detecting a second time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a second sensor comprising a second detector configured to be worn on the patient's body;(c) detecting sets of time-dependent motion waveforms with at least two motion-detecting sensors positioned on different locations on the patient's body, wherein each motion-detecting sensor detects a set of motion waveforms indicative of motion of the location on the patient's body to which the motion-detecting sensor is affixed;(d) processing the first and second time-dependent physiological waveforms to determine at least one vital sign from the patient;(e) analyzing at least a portion of each set of time-dependent motion waveforms, or a mathematical derivative thereof, to determine a motion parameter;(f) processing the motion parameter to determine a probability that the patient is undergoing a specific activity state; and(g) estimating the patient's activity state based on the probability,wherein step (e) further comprises analyzing a time-dependent variation of least one motion waveform, and comparing at least a portion of the motion waveform to a mathematical function. 3. A method for monitoring a patient, comprising the following steps: (a) detecting a first time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a first sensor comprising a first detector configured to be worn on the patient's body;(b) detecting a second time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a second sensor comprising a second detector configured to be worn on the patient's body;(c) detecting sets of time-dependent motion waveforms with at least two motion-detecting sensors positioned on different locations on the patient's body, wherein each motion-detecting sensor detects a set of motion waveforms indicative of motion of the location on the patient's body to which the motion-detecting sensor is affixed;(d) processing the first and second time-dependent physiological waveforms to determine at least one vital sign from the patient;(e) analyzing at least a portion of each set of time-dependent motion waveforms, or a mathematical derivative thereof, to determine a motion parameter;(f) processing the motion parameter to determine a probability that the patient is undergoing a specific activity state; and(g) estimating the patient's activity state based on the probability,wherein step (e) further comprises calculating an amplitude of at least one frequency component of the power spectrum, or a mathematical derivative thereof, to determine the motion parameter and determining a logit variable z, or a mathematical derivative thereof, wherein z is defined as: z=b0+b1x1+b2x2+ . . . +bmxm wherein b0, b1, b2, and bm are predetermined constants related to motion, and at least one of x0, x1, x2, and xm is a motion parameter determined from an amplitude of at least one frequency component of the power spectrum. 4. The method of claim 3, wherein step (f) further comprises processing the logit variable z, or a mathematical derivative thereof, with a mathematical function to determine the probability that the patient is undergoing a specific activity state. 5. The method of claim 4, wherein step (f) further comprises processing the logit variable z, or a mathematical derivative thereof, with a probability function P, or a mathematical derivative thereof, wherein P is defined as: P=11-exp(-z)and wherein P indicates a probability of an activity state. 6. The method of claim 5, wherein step (g) further comprises comparing P, or a mathematical derivative thereof, to a predetermined threshold value to estimate the patient's activity state. 7. The method of claim 5, wherein each of the first and second time-dependent physiological waveforms are selected from a group consisting of an optical waveform, an electrical waveform, an acoustic waveform, and a pressure waveform. 8. The method of claim 7, wherein steps (a) and (b) each further comprise detecting a time-dependent physiological waveform with a sensor selected from a group consisting of: (i) an optical sensor comprising a light source and a photodiode; (ii) an electrical sensor comprising at least two electrodes operably connected to an electrical circuit; (iii) an acoustic sensor comprising a microphone; and (iv) a pressure sensor comprising a transducer. 9. A method for monitoring a patient, comprising the following steps: (a) detecting a first time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a first sensor comprising a first detector configured to be worn on the patient's body;(b) detecting a second time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a second sensor comprising a second detector configured to be worn on the patient's body;(c) detecting sets of time-dependent motion waveforms with at least two motion-detecting sensors positioned on different locations on the patient's body, wherein each motion-detecting sensor detects a set of motion waveforms indicative of motion of the location on the patient's body to which the motion-detecting sensor is affixed;(d) processing the first and second time-dependent physiological waveforms to determine at least one vital sign from the patient;(e) analyzing at least a portion of each set of time-dependent motion waveforms, or a mathematical derivative thereof, to determine a motion parameter;(f) processing the motion parameter to determine a probability that the patient is undergoing a specific activity state; and(g) estimating the patient's activity state based on the probability,wherein step (e) further comprises analyzing a time-dependent variation of least one motion waveform, and determining a logit variable z, or a mathematical derivative thereof, wherein z is defined as: z=b0+b1x1+b2x2+ . . . +bmxm wherein b1, b1, b2, and bm are predetermined constants related to motion, and at least one of x0, x1, x2, and xm is a motion parameter determined from a time-dependent variation of least one motion waveform. 10. The method of claim 9, wherein step (f) further comprises processing the logit variable z, or a mathematical derivative thereof, with a mathematical function to determine the probability that the patient is undergoing a specific activity state. 11. The method of claim 10, wherein step (f) further comprises processing the logit variable z, or a mathematical derivative thereof, with a probability function P, or a mathematical derivative thereof, wherein P is defined as: P=11-exp(-z)and wherein P indicates a probability of an activity state. 12. The method of claim 11, wherein step (g) further comprises comparing P, or a mathematical derivative thereof, to a predetermined threshold value to estimate the patient's activity state. 13. The method of claim 9, wherein the first time-dependent physiological waveform is an electrical waveform, and step (a) further comprises detecting the electrical waveform with at least two electrodes attached to the patient and operably connected to an electrical circuit. 14. The method of claim 13, wherein the second time-dependent physiological waveform is an optical waveform, and step (b) further comprises detecting the optical waveform with an optical sensor comprising a light source and a photodiode. 15. A method for monitoring a patient, comprising the following steps: (a) detecting a first time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a first sensor comprising a first detector configured to be worn on the patient's body;(b) detecting a second time-dependent physiological waveform indicative of one or more contractile properties of the patient's heart with a second sensor comprising a second detector configured to be worn on the patient's body;(c) detecting sets of time-dependent motion waveforms with at least two motion-detecting sensors positioned on different locations on the patient's body, wherein each motion-detecting sensor detects a set of motion waveforms indicative of motion of the location on the patient's body to which the motion-detecting sensor is affixed;(d) processing the first and second time-dependent physiological waveforms to determine at least one vital sign from the patient;(e) analyzing at least a portion of each set of time-dependent motion waveforms, or a mathematical derivative thereof, to determine a motion parameter;(f) processing the motion parameter to determine a probability that the patient is undergoing a specific activity state; and(g) estimating the patient's activity state based on the probability,wherein step (d) further comprises determining at least one vital sign by calculating a time difference between a feature in the first time-dependent physiological waveform and a feature in the second time-dependent physiological waveform. 16. The method of claim 15, wherein step (d) further comprises calculating a blood pressure from the time difference.
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