System and method for performing an ocular irradiation procedure
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61F-009/007
A61B-018/18
A61N-005/01
출원번호
US-0027069
(2008-02-06)
등록번호
US-8506558
(2013-08-13)
발명자
/ 주소
Gertner, Michael
Arnoldussen, Mark
Herron, Matt
출원인 / 주소
Oraya Therapeutics, Inc.
대리인 / 주소
Hill, James W.
인용정보
피인용 횟수 :
8인용 특허 :
155
초록▼
A method and system for performing an ocular irradiation procedure on a patient's eye is disclosed. The system includes a head support for supporting the patient's head, an eye-contact device attachable to the front portion of the patient's eye, to stabilize the position of the eye; and a position d
A method and system for performing an ocular irradiation procedure on a patient's eye is disclosed. The system includes a head support for supporting the patient's head, an eye-contact device attachable to the front portion of the patient's eye, to stabilize the position of the eye; and a position detector for determining the position of the contact device in the external coordinate system. A source of a collimated electromagnetic radiation beam in the system is controlled by a beam-positioning assembly for positioning the beam source such that the beam, when activated, is aimed along a selected path at a selected coordinate in the external coordinate system corresponding to a selected target region in the patient's eye.
대표청구항▼
1. A system for performing an ocular irradiation procedure on a patient's eye, comprising (a) a head support for supporting the patient's head,(b) an eye-contact device attachable to the front portion of the patient's eye, to stabilize the position of the eye relative to the eye-contact device,(c) m
1. A system for performing an ocular irradiation procedure on a patient's eye, comprising (a) a head support for supporting the patient's head,(b) an eye-contact device attachable to the front portion of the patient's eye, to stabilize the position of the eye relative to the eye-contact device,(c) means for determining the position of the patient's eye, the eye being stabilized with respect to the contact device, and with the patient's head supported in the head support, in an external coordinate system,(d) a source of a collimated irradiation beam, and(e) a beam-positioning assembly for positioning the beam source in the external coordinate system such that the beam, when activated, is aimed along a selected path at a selected coordinate in the external coordinate system corresponding to a selected target region in the patient's eye;wherein said determining means includes a position detector for determining the position of the contact device, and thus the position of the patient's eye attached to the contact device, in the external coordinate system;wherein the system further includes an eye-positioning assembly for moving the eye-contact device to place the device at a selected position in the external coordinate system, and the position detector is operable to determine the position of the contact device in the external coordinate system, with such placed at said selected position;wherein the eye-positioning assembly is operable to adjust the angular position of the contact device with respect to the patient's head, and the position detector detects an angle of a beam emanating from the contact device;wherein the eye-contact device includes (i) a concave contact surface adapted to be placed against the front surface of a patient's eye, (ii) an outer surface, (iii) a port in fluid communication with the contact surface, by which a negative pressure can be applied between the eye and the contact surface, to stabilize the position of the eye with respect to the contact device, and (iv) a connector carried on the outer surface of the device, and the system further includes a biasing mechanism coupled to the connector of the contact device for pressing the eye-contact device against the eye with a force sufficient to the hold the contact device against the eye, when the eye is stabilized with respect to the device by application of a negative pressure between the eye and the device's contact surface;wherein the eye-positioning assembly includes an arm that is pivotally attached to the connector of the eye-contact device, and an arm control mechanism for controlling the movement of the arm in at least one direction in the external coordinate system, and the position detector is operable to determine the position of the contact device in the external coordinate system from the position of the eye-positioning assembly arm in the external coordinate system;wherein said determining means includes a reference-beam light source operatively connected to the irradiation-beam source, for producing a reference light beam along a path coincident with the collimated irradiation beam produced by the irradiation beam source, and said beam-positioning assembly is operable to place the irradiation beam source at a position such that the collimated irradiation beam is aimed at the selected target region of patient's eye. 2. The system of claim 1, wherein the position detector includes a plurality of beam elements mounted on the contact device, for directing beams in accordance with the position and orientation of the beam elements, sensors for detecting the directions of the beams, and a processor for determining from the detected beam directions, the position and orientation of the contact device in the external coordinate system. 3. The system of claim 1, which further includes a vacuum source operable to apply a negative pressure of between about 20-50 mm Hg to the contact device contact surface. 4. The system of claim 1, for use in treating macular degeneration in a patient eye, wherein the beam source is a source of soft collimated x-rays, and the beam-positioning assembly is operable to position the beam source to direct a collimated x-ray beam at the macular region of the eye, along a path through an outer side region of the eye that makes an angle with an axis normal to the cornea of the eye, between about 5 and 45 degrees. 5. The system of claim 1, wherein the eye-contact device is a curved structure which is centered on a center axis extending through the contact device, substantially normal thereto, and said connector is disposed along the center axis of the contact device. 6. The system of claim 1, wherein the eye-contact device is a curved structure which is centered on a center axis extending through the contact device, substantially normal thereto, and said connector is disposed along an axis offset from the center axis. 7. The system of claim 1, wherein the connector is detachably coupled to the biasing mechanism, allowing the mechanism to break away from the eye-contact device when an above-threshold force is applied by or to the eye. 8. A system for performing an ocular irradiation procedure on a patient's eye, comprising (a) a head support for supporting the patient's head,(b) an eye-contact device attachable to the front portion of the patient's eye, to stabilize the position of the eye relative to the eye-contact device,(c) means for determining the position of the patient's eye, with the eye being stabilized with respect to the contact device, and with the patient's head supported in the head support, in an external coordinate system,(d) a source of a collimated irradiation beam, and(e) a beam-positioning assembly for positioning the beam source in the external coordinate system such that the beam, when activated, is aimed along a selected path at a selected coordinate in the external coordinate system corresponding to a selected target region in the patient's eye;(f) a position detector for determining the position of the contact device, and thus the position of the patient's eye attached to the contact device, in the external coordinate system(g) an eye-positioning assembly operable to adjust the angular position of the contact device with respect to the patient's head, the position detector being operable to detect an angle of a beam emanating from the contact device;wherein the eye-contact device includes (i) a concave contact surface adapted to be placed against the front surface of a patient's eye, (ii) an outer surface, (iii) a port in fluid communication with the contact surface, by which a negative pressure can be applied between the eye and the contact surface, to stabilize the position of the eye with respect to the contact device, and (iv) a connector carried on the outer surface of the device, and the system further includes a biasing mechanism coupled to the connector of the contact device for pressing the eye-contact device against the eye with a force sufficient to the hold the contact device against the eye, when the eye is stabilized with respect to the device by application of a negative pressure between the eye and the device's contact surface;wherein the eye-positioning assembly includes an arm that is pivotally attached to the connector of the eye-contact device, and an arm control mechanism for controlling the movement of the arm in at least one direction in the external coordinate system, and the position detector is operable to determine the position of the contact device in the external coordinate system from the position of the eye-positioning assembly arm in the external coordinate system;wherein said determining means includes a reference-beam light source operatively connected to the irradiation-beam source, for producing a reference light beam along a path coincident with the collimated irradiation beam produced by the irradiation beam source, and said beam-positioning assembly is operable to place the irradiation beam source at a position such that the collimated irradiation beam is aimed at the selected target region of patient's eye. 9. The system of claim 8, wherein the position detector includes a plurality of beam elements mounted on the contact device, for directing beams in accordance with the position and orientation of the beam elements, sensors for detecting the directions of the beams, and a processor for determining from the detected beam directions, the position and orientation of the contact device in the external coordinate system. 10. The system of claim 8, which further includes a vacuum source operable to apply a negative pressure of between about 20-50 mm Hg to the contact device contact surface. 11. The system of claim 8, for use in treating macular degeneration in a patient eye, wherein the beam source is a source of soft collimated x-rays, and the beam-positioning assembly is operable to position the beam source to direct a collimated x-ray beam at the macular region of the eye, along a path through an outer side region of the eye that makes an angle with an axis normal to the cornea of the eye, between about 5 and 45 degrees. 12. The system of claim 8, wherein the eye-contact device is a curved structure which is centered on a center axis extending through the contact device, substantially normal thereto, and said connector is disposed along the center axis of the contact device. 13. The system of claim 8, wherein the eye-contact device is a curved structure which is centered on a center axis extending through the contact device, substantially normal thereto, and said connector is disposed along an axis offset from the center axis. 14. The system of claim 8, wherein the connector is detachably coupled to the biasing mechanism, allowing the mechanism to break away from the eye-contact device when an above-threshold force is applied by or to the eye.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (155)
Feichtner John D. (Los Altos Hills CA) Depp Joseph G. (San Jose CA), 3-dimensional radiation dosimeter.
Fu,Dongshan; Kuduvalli,Gopinath; Qureshi,Shehrzad, Apparatus and method for registering 2D radiographic images with images reconstructed from 3D scan data.
Chandler William P. ; Hartmann-Siantar Christine L. ; Rathkopf James A., Calculation of radiation therapy dose using all particle Monte Carlo transport.
Wallace David A. (Beverly Hills CA) Feldon Steven E. (San Marino CA) Mezack Gary (Norco CA) Whiting Douglas L. (South Pasadena CA) Dally William J. (Pasadena CA) Karns Scott A. (Pomona CA), Digital ultrasonic instrument for ophthalmic use.
Hsueh Chi-Fu (Escondido CA) Morris Gregory J. (La Jolla CA) Goelz Stefan (Plankstadt DEX), Eye stabilizing mechanism for use in ophthalmic laser surgery.
Blumhofer, Andreas; Fr?hlich, Stephan; Lachner, Rainer; Schlossbauer, Cornel, Method and device for accurately positioning a patient in radiotherapy and/or radiosurgery.
Wessol, Daniel E.; Frandsen, Michael W.; Wheeler, Floyd J.; Nigg, David W., Methods and computer readable medium for improved radiotherapy dosimetry planning.
Webb, Kyle R.; Brownell, Michael F.; Horvath, Christopher; Juhasz, Tibor; Kurtz, Ronald M.; Nagy, Laszlo I.; Ross, Mark W.; Suarez, Carlos G., Ocular fixation and stabilization device for ophthalmic surgical applications.
Fu, Dongshan; Saracen, Michael J.; Kuduvalli, Gopinath, Precision registration of X-ray images to cone-beam CT scan for image-guided radiation treatment.
Fu, Dongshan; Khan, Robert D.; Wang, Hongwu; Wang, Bai; Mu, Zhiping; Core, Matthew A.; Kuduvalli, Gopinath; Maurer, Jr., Calvin R., Target tracking using direct target registration.
Smith Donald O. (Lexington MA) Sliski Alan P. (Lincoln MA) Harte Kenneth J. (Carlisle MA) Dinsmore Mark T. (Sudbury MA), X-ray source with shaped radiation pattern.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.