IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
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출원번호 |
US-0118081
(2005-04-29)
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등록번호 |
US-8506646
(2013-08-13)
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발명자
/ 주소 |
- McKay, William F.
- Scifert, Jeffrey L.
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출원인 / 주소 |
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대리인 / 주소 |
Sorell Lenna & Schmidt LLP
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인용정보 |
피인용 횟수 :
0 인용 특허 :
32 |
초록
▼
Described are medical devices for supporting or inducing bone growth including an implant body defining one or more separation-assist lines that facilitate separation of the body into two or more substantially pre-defined pieces. The implant body can be used and implanted as a whole or may be separa
Described are medical devices for supporting or inducing bone growth including an implant body defining one or more separation-assist lines that facilitate separation of the body into two or more substantially pre-defined pieces. The implant body can be used and implanted as a whole or may be separated into multiple pieces, some or all of which can be used at one or multiple implant sites in a patient. Separation-assist lines in implant bodies can serve a dual role in imparting increased and controlled flexibility to the overall body when used as a whole at an implant site. Also described are methods of making and using, and kits including, such medical devices.
대표청구항
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1. A medical implant device, comprising: a biocompatible, three-dimensional osteoconductive or osteoinductive implant body, the implant body comprising a sponge including mineral particles disposed uniformly within the sponge, said body including an upper surface, a lower surface, and side walls int
1. A medical implant device, comprising: a biocompatible, three-dimensional osteoconductive or osteoinductive implant body, the implant body comprising a sponge including mineral particles disposed uniformly within the sponge, said body including an upper surface, a lower surface, and side walls interconnecting the upper surface and the lower surface, wherein the implant body has a thickness of from 2 cm to 15 cm; and at least one separation-assist line defined in said implant body, said separation-assist line configured to facilitate separation of a first portion of the implant body from a second portion of the implant body by manipulating the implant body to manually break or tear the implant body along the separation-assist line into multiple separate pieces, wherein said separation-assist line comprises at least a first score line extending inwardly from a first surface of said implant body and at least a second score line extending inwardly from a second surface of said implant body, said second score line oppositely faced to and aligned with said first score line, and said first score line and second score line having a depth that comprises 20% to 60% of said thickness of the implant body and the sponge comprising fibrillar and non-fibrillar collagen and the implant comprises a plurality of said separation-assist lines extending only partially across a width of the implant body. 2. The medical implant device of claim 1, wherein said sponge includes a porous matrix comprising a synthetic or naturally occurring polymer. 3. The medical implant device of claim 1, wherein the first score line and the second score line have a thickness that comprises 20% of said thickness of the implant body. 4. The medical implant device of claim 1, wherein said mineral particles comprise biphasic calcium phosphate. 5. The medical implant device of claim 1, wherein, said separation-assist lines are configured to facilitate separation of the implant body into two to ten pieces. 6. The medical implant device of claim 5, wherein said pieces each have a volume of about 1 cc to about 50 cc. 7. The medical implant device of claim 5, wherein said implant body has a volume of about 2 cc to about 100 cc. 8. The medical implant device of claim 1, wherein said implant body is osteoconductive. 9. The medical implant device of claim 1, wherein said implant body is osteoinductive. 10. The medical implant device of claim 1, wherein the sponge comprises collagen and the weight ratio of said mineral particles to said collagen is at least 4:1. 11. The medical implant device of claim 1, wherein said collagen comprises Type I collagen. 12. The medical implant device of claim 1, wherein said implant body is formed of a flexible material having an ability to conform to an implant site at which bone growth is desired. 13. A medical implant device according to claim 1, wherein the implant further comprises peripheral portions that are thicker than the at least one separation-assist line, the peripheral portions configured to reinforce the implant. 14. A medical device suitable for implant to support or induce bone growth, the device comprising: an osteoinductive or osteoconductive implant body, said implant body defining at least one separation-assist line configured to facilitate separation of a first portion of the implant body from a second portion of the implant body into multiple separate pieces by manipulating the implant body to manually break or tear the implant body along the separation-assist line, and said implant body comprises a sponge and a mineral disposed uniformly throughout the sponge, and the implant body has a thickness of from 2 cm to 15 cm, and wherein said separation-assist line comprises at least a first score line extending inwardly from a first surface of said implant body and at least a second score line extending inwardly from a second surface of said implant body, said second score line oppositely faced to and aligned with said first score line, and said first score line and second score line having a depth that comprises 20% to 60% of said thickness of the implant body and the sponge comprises fibrillar and non-fibrillar collagen and the implant comprises a plurality of said separation-assist lines extending only partially across a width of the implant body. 15. The medical device of claim 14, wherein said implant body comprises a resorbable flexible material having an ability to conform to an implant site at which bone growth is desired. 16. The medical device of claim 15, wherein the first score line and the second score line have a depth that comprises 20% of the thickness of the implant body. 17. A medical product, comprising: an osteoinductive or osteoconductive implant body, said implant body defining at least one separation-assist line configured to facilitate separation of a first portion of the implant body from a second portion of the implant body by manipulating the implant body to manually break or tear the implant body along the separation-assist line into multiple separate pieces; and packaging enclosing said implant body in a sterile condition, wherein said implant body comprises a sponge and a mineral disposed uniformly throughout the sponge and said implant body has a thickness of from 2 cm to 15 cm and wherein said separation-assist line comprises at least a first score line extending inwardly from a first surface of said implant body and at least a second score line extending inwardly from a second surface of said implant body, said second score line opposite faced to and aligned with said first score line, and said first score line and second score line having a depth that comprises 20% to 60% of said thickness of the implant body and the sponge comprises fibrillar and non-fibrillar collagen and the implant comprises a plurality of said separation-assist lines extending only partially across a width of the implant body. 18. The medical product of claim 17, wherein said implant body comprises a natural or synthetic polymer, wherein said implant body is formed of a flexible material having an ability to conform to an implant site at which bone growth is desired, and further wherein said at least one separation-assist line increases the flexibility of the implant body.
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