A system for separating components of a composition according to density. The system includes a torque generating device, a separation device, and a housing. The separation device separates the composition into different components according to density. The housing accommodates the separation device
A system for separating components of a composition according to density. The system includes a torque generating device, a separation device, and a housing. The separation device separates the composition into different components according to density. The housing accommodates the separation device. The housing includes a base having an interface that transfers torque from the torque generating device to the separation device, a cover, and a conduit for introducing the composition into the separation device without opening the cover.
대표청구항▼
1. A system for separating components of a composition according to density comprising: a torque generating device;a separation device for separating the composition into different components according to density, the separation device including: a first end and a second end opposite to the first en
1. A system for separating components of a composition according to density comprising: a torque generating device;a separation device for separating the composition into different components according to density, the separation device including: a first end and a second end opposite to the first end, wherein a longitudinal axis extends between the first end and the second end;a sidewall extending between the first end and the second end, the sidewall defining a separation chamber;a separator within the separation chamber along the longitudinal axis;an inlet port and an outlet port each extending through the sidewall between the first end and the second end; anda counterbalance between the second end and the inlet port; anda housing that accommodates the separation device to maintain the separation device in a sterile condition when seated therein;wherein the torque generating device is external to the housing and is configured to supply torque to the separation device when seated in the housing. 2. The system of claim 1, wherein the torque generating device includes a motorized rotating platform. 3. The system of claim 1, wherein the separator includes a buoy slidable along the longitudinal axis having a density less than that of red blood cells of whole blood. 4. A separation device for separating components of a composition according to density comprising: a first end, a second end, a sidewall that extends between the first end and the second end to define a separation chamber, wherein a longitudinal axis extends through the separation chamber between the first end and the second end;a separator slidably mounted within the separation chamber along the longitudinal axis and having a density such that the separator is operable to move to an equilibrium between two of the components to be separated after the separation device is rotated;a first outlet port including a first outlet tube that extends from a first side of the sidewall and through the buoy to provide fluid communication between an exterior of the separation device and a first area of the separation chamber between the separator and the second end;a second outlet port including a second outlet tube that extends from the first side of the sidewall to a second area of the separation chamber that is between the first end and the buoy separator; anda coupling device at a second side of the sidewall that is opposite to the first side of the sidewall surface, the coupling device is configured to receive torque generated by a torque generating device;wherein upon rotation of the separation device about a midpoint between the first end and the second end along the longitudinal axis in a plane that is perpendicular to a longitudinal axis along which the torque is applied, the separator is operable to separate a first component of the composition having a first density from a second component of the composition having a second density, the first component is isolated in the first area of the separation chamber and the second component is isolated in the second area of the separation chamber. 5. The separation device of claim 4, further comprising an inlet port that provides fluid communication with an interior of the separation device, the inlet port is at the first side of the sidewall and spaced apart from the first and second outlet ports. 6. The separation device of claim 4, wherein a first distance between the first end and the second end is greater than a second distance between the first side of the sidewall and the second side of the sidewall. 7. The separation device of claim 4, wherein the separator further includes a buoy and a divider that is spaced apart from the buoy and mounted to the buoy to define a collection compartment between the divider and the buoy; wherein the first outlet tube extends across the collection compartment to the divider. 8. A device for separating components of a composition according to density comprising: a separation device including: a first end, a second end opposite to the first end, a cylindrical sidewall extending between the first end and the second end to define a separation chamber, and a longitudinal axis extending through an axial center of the separation chamber from the first end to the second end;a counter-balance within the separation chamber and proximate to the first end;a separator including a buoy within the separation chamber and slidably mounted along the longitudinal axis between the second end and the counter-balance;a divider mounted to the buoy at a side of the buoy proximate to the second end, the buoy has a density such that it is operable to move to an equilibrium between two of the components to be separated;a first outlet port including a first outlet tube that extends from a first side of the sidewall to the divider, the first outlet tube extends through the buoy;a second outlet port including a second outlet tube that extends from the first side of the sidewall to a location within the separation chamber that is between the counter-balance and the buoy;an inlet port that provides fluid communication between an exterior of the separation device and the separation chamber, the inlet port is at the first side of the sidewall and spaced apart from the first and second outlet ports; anda locking device at a second side of the sidewall that is opposite to the first side and is operable to cooperate with a rotating platform to rotate the separation device; andan outer housing including a base and a sidewall that define a receptacle that accommodates the separation device and includes an interface operable to transfer torque from the rotating platform to the separation device when the separation device is seated in the receptacle;a cover configured to engage the outer housing to provide a seal therebetween and maintain the separation device in a sterile condition when seated within the receptacle, the cover includes a conduit extending therethrough, the conduit is operable to cooperate with the inlet port when the separation device is seated in the receptacle to permit introduction of the composition through the cover and into the separation device through the inlet port while the separation device is maintained in a sterile condition;wherein the rotating platform is external to the outer housing and is selectively coupled to the outer housing at the interface to supply torque to the separation device; andwherein upon rotation of the separation device by the rotating platform about a midpoint between the first end and the second end along the longitudinal axis in a plane that is perpendicular to a longitudinal axis along which the torque is applied and restricting rotation of the separation device about the longitudinal axis, the separator is operable to separate a first component of the composition having a first density from a second component of the composition having a second density, the first component is separated in a first area of the separation chamber between the divider and the first end and the second component is separated in a second area of the separation chamber between the divider and the second end. 9. The system of claim 1, wherein the sidewall is cylindrical and the longitudinal axis extends through an axial center of the separation chamber. 10. The system of claim 1, wherein the sidewall includes a locking device that is at a first portion of the sidewall opposite to a second portion of the sidewall including the inlet port and the outlet port, the locking device is configured to engage an interface at a base of the housing that transfers torque from the torque generating device to the housing. 11. The system of claim 1, wherein the housing further comprises: a base;a cover configured to selectively engage one of the separation device or the housing to provide a seal therebetween that maintains the separation device in a sterile condition when seated in the housing; anda conduit extending through the cover and in communication with the inlet port for introducing the composition into the separation device without opening the cover to maintain the separation device in a sterile condition as the composition is introduced;wherein the torque generating device is external to the housing and selectively coupled to the housing at the base. 12. The system of claim 11, wherein the cover is mounted directly to the separation device and rotates with the separation device. 13. The system of claim 11, wherein the cover is mounted directly to the housing and is stationary when the separation device is rotating. 14. The system of claim 11, wherein the conduit is movable to selectively engage and disengage the separation device without removing the cover. 15. A system for separating components of a composition according to density comprising: A separation device including: A first end and a second end opposite to the first end, wherein a first longitudinal axis extends between the first end and the second end;A sidewall extending between the first end and the second end, the sidewall defining a separation chamber;A movable buoy within the separation chamber for separating components of the composition according to density; andAn inlet port and an outlet port each extending through the sidewall between the first end and the second end;A housing including a base, a housing sidewall extending from the base, and a cover, the housing defines a compartment configured to receive the separation device therein such that the first longitudinal axis is substantially parallel to the base, and maintain the separation device in a sterile condition; andA torque generating device external to the housing and selectively coupled to the housing to transfer torque to the separation device when seated in the compartment to rotate the separation device about a midpoint between the first end and the second end along the first longitudinal axis in a plane that is both substantially perpendicular to a second longitudinal axis along which the torque is applied and substantially parallel to the base. 16. The system of claim 15, wherein a first distance between the first end and the second end is greater than a second distance between opposing sides of the sidewall. 17. The system of claim 15, wherein the sidewall is a cylindrical sidewall. 18. The system of claim 15, wherein the movable buoy includes a buoy movable along the first longitudinal axis. 19. The system of claim 15, further comprising a counterbalance within the separation chamber at the second end, the separator is closer to the first end than to the second end. 20. The system of claim 15, further comprising a conduit extending through the cover and in communication with the inlet port for introducing the composition into the separation device without opening the cover to maintain the separation device in a sterile condition as the composition is introduced, the conduit is movable to selectively engage and disengage the separation device without removing the cover.
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