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Vectors expressing SARS immunogens, compositions containing such vectors or expression products thereof, methods and assays for making and using

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-039/12
  • A61K-039/215
  • C12P-019/34
  • C12P-021/04
  • C12P-021/06
  • C12N-015/09
  • C12N-015/63
  • C12N-015/64
  • C12N-015/66
출원번호 US-0873424 (2004-06-21)
등록번호 US-8541003 (2013-09-24)
발명자 / 주소
  • Anderson, D. Karl
  • Holtz-Corris, Kathleen M.
  • Chubet, Rick
  • Adams, Daniel
  • Cox, Manon
출원인 / 주소
  • Protein Sciences Corporation
대리인 / 주소
    Vedder Price P.C.
인용정보 피인용 횟수 : 1  인용 특허 : 41

초록

SARS (severe acute respiratory syndrome virus, a coronavirus) immunogens, antigens, or epitopes, nucleic acid molecules encoding such immunogens, antigens, or epitopes; vectors containing such nucleic acid molecules, e.g., viral vectors such as baculovirus vectors, DNA vectors, such as DNA plasmid v

대표청구항

1. A recombinant baculovirus vector that expresses: (a) a baculovirus signal peptide; and(b) a SARS S protein,wherein expression of the SARS S protein is under control of a polyhedrin promoter. 2. The recombinant baculovirus vector of claim 1, wherein the baculovirus signal peptide comprises an amin

이 특허에 인용된 특허 (41)

  1. Matsuo Kazuhiro,JPX ; Chujo Yoshitomo,JPX ; Yamazaki Akihiro,JPX ; Honda Mitsuo,JPX ; Yamazaki Shudo,JPX ; Tasaka Hiromichi,JPX, Anti-acids secretory recombinant BCG vaccine.
  2. Barbour Alan George ; Bergstrom Sven,SEX ; Hansson Lennart,SEX, Borrelia burdorferi Osp A and B proteins and immunogenic peptides.
  3. Timothy J. Miller ; Sharon Klepfer ; Albert Paul Reed ; Elaine V. Jones, Canine coronavirus S gene and uses therefor.
  4. Audonnet Jean-Christophe,FRX ; Baudu Philippe,FRX, Canine herpesvirus based recombinant live vaccine, in particular against canine distemper, rabies or the parainfluenza 2 virus.
  5. Rota,Paul A.; Anderson,Larry J.; Bellini,William J.; Burns,Cara Carthel; Campagnoli,Raymond; Chen,Qi; Comer,James A.; Emery,Shannon L.; Erdman,Dean D.; Goldsmith,Cynthia S.; Humphrey,Charles D.; Icen, Coronavirus isolated from humans.
  6. Pillai Subramonia (Rochester NY) Eby Ronald (Rochester NY), Cytokine and hormone carriers for conjugate vaccines.
  7. Briles David E. ; Yother Janet L., DNA encoding a truncated pneumogoccal surface protein (PspA).
  8. Briles David E. ; Yother Janet L. ; McDaniel Larry S., Epitopic regions of pneumococcal surface protein A.
  9. Briles David E. ; Yother Janet L. ; McDaniel Larry S., Epitopic regions of pneumococcal surface protein A.
  10. Briles David E. ; Yother Janet L. ; McDaniel Larry S. ; Wu Hong-Yin, Epitopic regions of pneumococcal surface protein a.
  11. Briles David E. ; Yother Janet L., Immunoassay comprising a truncated pneumococcal surface protein A (PspA).
  12. David Gary S. (La Jolla CA) Greene Howard E. (Carlsbad CA), Immunometric assays using monoclonal antibodies.
  13. Smith Gale Eugene ; DeBartolomeis James ; Voznesenski Andrei Igorevitch, Insect cells or fractions as adjuvant for antigens.
  14. Smith Gale E. (Bryan TX) Summers Max D. (Bryan TX), Method for producing a recombinant baculovirus expression vector.
  15. Smith Gale E. (Bryan TX) Summers Max D. (Bryan TX), Method for producing a recombinant baculovirus expression vector.
  16. Smith Gale E. ; Volvovitz Franklin ; Wilkinson Bethanie E. ; Voznesensky Andrei I. ; Hackett Craig S., Method for producing influenza hemagglutinin multivalent vaccines.
  17. Smith Gale Eugene ; Volvovitz Franklin ; Wilkinson Bethanie Eident ; Hackett Craig Stanway, Method for producing influenza hemagglutinin multivalent vaccines using baculovirus.
  18. Koprowski Hilary (Wynnewood PA) Gerhard Walter U. (Philadelphia PA) Croce Carlo M. (Philadelphia PA), Method of producing antibodies.
  19. Briles David E. ; Wu Hong-Yin, Mucosal administration of pneumococcal antigens.
  20. Gail Eugene Smith ; James T. Matthews ; Edwin D. Kilbourne ; Bert E. Johansson ; Bethanie E. Wilkinson ; Andrei I. Voznesensky ; Craig S. Hackett ; Franklin Volvovitz, Neuraminidase-supplemented compositions.
  21. Briles David E. ; McDaniel Larry S. ; Yamamoto Masafumi ; Kiyono Hiroshi, Oral administration of pneumoccal antigens.
  22. Briles David E. ; McDaniel Larry S. ; Yamamoto Masafumi ; Kiyono Hiroshi, Oral administration of pneumococcal antigens.
  23. Briles David E. ; McDaniel Larry S. ; Yamamoto Masafumi ; Kiyono Hiroshi, Oral administration of pneumococcal antigens.
  24. David E. Briles ; Larry S. McDaniel ; Edwin Swiatlo ; Janet Yother ; Marilyn J. Crain ; Susan Hollingshead ; Rebecca Tart ; Alexis Brooks-Walter, Pneumococcal surface proteins and uses thereof.
  25. Audonnet Jean-Christophe,FRX ; Bouchardon Annabelle,FRX ; Riviere Michel,FRX, Polynucleotide vaccine formula against canine pathologies.
  26. Souza Lawrence M. (Thousand Oaks CA), Production of human pluripotent granulocyte colony-stimulating factor.
  27. Dunn Ashley R. (North Balwyn AUX) Gough Nicholas M. (North Balwyn AUX) Metcalf Donald (Balwyne AUX), Recombinant DNA molecules.
  28. Wasmoen Terri ; Chu Hsien-Jue, Recombinant feline Immunodeficiency virus subunit vaccines employing baculoviral-expressed envelope glycoproteins derive.
  29. Paoletti Enzo ; Gettig Russell, Recombinant poxvirus-feline infectious peritionitis virus, compositions thereof and methods for making and using them.
  30. Dale Beverly ; Yamanaka Miles ; Acree William M. ; Chavez ; Jr. Lloyd G., Recombinant structural and non-structural proteins of FIPV and method of immunizing.
  31. Jean-Christophe Francis Audonnet FR; Philippe Guy Nicolas Baudu FR; Michel Albert Emile Riviere FR, Recombinant vaccine containing feline herpes virus type 1 particularly for treating feline infectious peritonitis.
  32. Smith Gale E. ; Foellmer Harald G. ; Knell John ; DeBartolomeis James ; Voznesensky Andrei I., Spodoptera frugiperda single cell suspension cell line in serum-free media, methods of producing and using.
  33. Briles David E. ; Hollingshead Susan ; Becker Robert, Strain selection of pneumococcal surface proteins.
  34. Briles David E. (Birmingham AL) Yother Janet L. (Birmingham AL) McDaniel Larry S. (Birmingham AL), Structural gene of pneumococcal protein.
  35. Briles David E. ; Yother Janet L., Structural gene of pneumococcal protein.
  36. Briles David E. ; Yother Janet L., Structural gene of pneumococcal protein.
  37. Taizou Sugioka JP; Shinichi Miura JP; Masami Mihara JP; Shinobu Yamao JP; Masahiro Nakamichi JP, Styrenic resin composition and semiconductor carrier device.
  38. Alving Carl R. ; Glenn Gregory M., Transdermal delivery system for antigen.
  39. Briles David E. ; Yother Janet L., Truncated PSPA lacking a functional cell membrane anchor region.
  40. Smith Gale E. ; Volvovitz Franklin ; Wilkinson Bethanie E. ; Voznesensky Andrei I. ; Hackett Craig S., Vaccine comprising a baculovirus produced influenza hemagglutinin protein fused to a second protein.
  41. Briles David E. ; Wu Hong-Yin, immunogenic compositions for mucosal administration of pneumococcal surface protein A (PspA).

이 특허를 인용한 특허 (1)

  1. Lawrence, Paulraj; Bey, Russell, Recombinant spike protein subunit based vaccine for porcine epidemic diarrhea virus (PEDV).
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