Compositions and methods for therapeutic delivery with frozen particles
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-051/00
A61K-009/14
A61K-009/00
출원번호
US-0380568
(2009-02-26)
등록번호
US-8551505
(2013-10-08)
발명자
/ 주소
Boyden, Edward S.
Hyde, Roderick A.
Leuthardt, Eric C.
Myhrvold, Nathan P.
Sweeney, Elizabeth A.
Wood, Jr., Lowell L.
출원인 / 주소
The Invention Science Fund I, LLC
인용정보
피인용 횟수 :
0인용 특허 :
159
초록▼
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particula
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
대표청구항▼
1. A method of providing at least one therapeutic agent to at least one biological tissue of a subject, comprising: delivering at least one therapeutic composition including at least one anti-inflammatory agent to at least one biological tissue, wherein the at least one therapeutic composition inclu
1. A method of providing at least one therapeutic agent to at least one biological tissue of a subject, comprising: delivering at least one therapeutic composition including at least one anti-inflammatory agent to at least one biological tissue, wherein the at least one therapeutic composition includes one or more frozen particles including at least one frozen gas of helium, neon, xenon, krypton, or bromine, andwherein delivering includes delivering by propulsion at a predetermined pressure. 2. The method of claim 1, wherein the at least one therapeutic composition is propelled to a desired location of the at least one biological tissue. 3. The method of claim 1, wherein delivering at least one therapeutic composition includes accelerating the therapeutic composition toward at least one biological tissue. 4. The method of claim 3, wherein the at least one therapeutic composition is accelerated to a predetermined velocity for delivery of the at least one therapeutic composition to a desired location of the at least one biological tissue. 5. The method of claim 1, wherein delivering at least one therapeutic composition to at least one biological tissue includes propelling a plurality of therapeutic compositions toward the at least one biological tissue. 6. The method of claim 1, wherein delivering the at least one therapeutic composition occurs prior to, during, or subsequent to surgery. 7. The method of claim 1, wherein the at least one biological tissue is located in at least one of in situ, in vitro, in vivo, in utero, in planta, or ex vivo. 8. The method of claim 1, wherein the at least one biological tissue is transplanted or implanted into at least one subject. 9. The method of claim 7, wherein the at least one biological tissue is ingested by at least one subject. 10. The method of claim 7, wherein the at least one biological tissue includes at least one biological tissue from at least one donor or recipient. 11. The method of claim 7, wherein the at least one biological tissue includes at least one cell mass. 12. The method of claim 11, wherein the at least one cell mass includes at least one benign or malignant tumor. 13. The method of claim 1, further including delivering to the at least one biological tissue at least one of a polymer, biopolymer, nanoparticle, or detection material. 14. The method of claim 13, wherein the detection material includes at least one electronic identification device. 15. The method of claim 14, wherein the at least one electronic identification device includes at least one radio frequency identification device. 16. The method of claim 13, wherein the detection material includes at least one radioactive element. 17. The method of claim 13, wherein the detection material includes at least one colorimetric substance. 18. The method of claim 13, wherein the detection material includes at least one of a diamagnetic particle, ferromagnetic particle, paramagnetic particle, super paramagnetic contrast agent, or other magnetic particle. 19. The method of claim 1, wherein the subject includes at least one invertebrate or vertebrate animal. 20. The method of claim 1, wherein the subject includes at least one human. 21. The method of claim 19, wherein the subject includes at least one of livestock, pet, undomesticated herd animal, wild animal, or a product animal. 22. The method of claim 1, wherein the at least one therapeutic composition further includes one or more reinforcement agents. 23. The method of claim 1, wherein the at least one therapeutic composition further includes one or more explosive materials. 24. A method of providing at least one therapeutic agent to at least one biological tissue, comprising: delivering at least one therapeutic composition to at least one biological tissue of a subject;wherein the at least one therapeutic composition includes one or more frozen particles including at least one frozen gas of helium, neon, xenon, krypton, bromine; and includespaclitaxel; and wherein the delivering includes delivering by propulsion at a predetermined pressure. 25. The method of claim 24, wherein the at least one therapeutic composition further includes one or more reinforcement agents. 26. The method of claim 24, wherein the at least one therapeutic composition further includes one or more explosive materials.
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Topalian Harry H. (Dover DE) Wyss Clement R. (Lewes DE) Kenyon Ralph E. (Dover DE) Dec Anthony F. (Dover DE), Frozen aerated ready-to-eat gelatin composition.
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Brinegar Chris (587 Locksley Rd. Boulder Creek CA 95006) Gilmore James (6385 Camino Verde Dr. San Jose CA 95119) Johnson Michael (6385 Camino Verde Dr. San Jose CA 95119) Walker Nigel (5385 Broadway , Ice-mediated introduction of substances into biological material.
Power Wendy ; Reed Michael A. ; Frustaci Dominick J. ; Larocque Gerald ; Marchetti Brenda, Method and apparatus for determining quantity of liquid in a container and/or lack of motion thereof.
Westergaard Knud E. (Rolighedsvej 16 9560 Hadsund DKX), Method and apparatus for particle blasting using particles of a material that changes its state.
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Cates Michael C. (Solana Beach CA) Hamm Richard R. (San Diego CA) Lewis Michael W. (Wichita KS) Schmitz Wayne N. (St. Louis MO), Method and system for removing a coating from a substrate using radiant energy and a particle stream.
Sanford John C. (Geneva NY) Wolf Edward D. (Ithaca NY) Allen Nelson K. (Newfield NY), Method for transporting substances into living cells and tissues and apparatus therefor.
Bellhouse Brian J. (Islip GB2) Sarphie David F. (Witney GB2) Greenford John C. (Abingdon GB2), Method of delivering powder transdermally with needless injector.
Costantino Henry R. ; Jaworowicz Warren E. ; Tracy Mark A. ; Beganski Christopher P., Method of producing sub-micron particles of biologically active agents and uses thereof.
Cummins Thomas J. (Rochester NY) Ekeze Tobias D. (Rochester NY), Methods of extracting nucleic acids and PCR amplification without using a proteolytic enzyme.
Rhim Won-Kyu (Pasadena CA) Hyson Michael T. (Glendale CA) Chung Sang-Kun (Diamond Bar CA) Colvin Michael S. (Malibu CA) Chang Manchium (Los Angeles CA), Monodisperse, polymeric microspheres produced by irradiation of slowly thawing frozen drops.
Shih, Hong; Leonte, Oana M.; Daugherty, John E.; Huang, Tuochuan; Goldspring, Gregory J.; May, Michael C., On-line chamber cleaning using dry ice blasting.
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