Apple peel powder, methods of making, and uses thereof
IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0018833
(2004-12-20)
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등록번호 |
US-8551554
(2013-10-08)
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발명자
/ 주소 |
|
출원인 / 주소 |
- Cornell Research Foundation, Inc.
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대리인 / 주소 |
LeClairRyan, a Professional Corporation
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인용정보 |
피인용 횟수 :
0 인용 특허 :
10 |
초록
▼
The present invention relates to a method of making a powder from apple peel by providing an apple peel, subjecting the apple peel to a phytochemical preservation treatment, drying the treated apple peel, and grinding the dried, treated apple peel to a powder. A powder from apple peel having a pheno
The present invention relates to a method of making a powder from apple peel by providing an apple peel, subjecting the apple peel to a phytochemical preservation treatment, drying the treated apple peel, and grinding the dried, treated apple peel to a powder. A powder from apple peel having a phenolic content and a flavonoid content similar to fresh apple peel on a fresh weight basis, where the powder has a water activity of less than 0.30 is also disclosed. The present invention also relates to a method of treating cancer in a patient by administering a powder from apple peel to a patient under conditions effective to treat cancer. Also disclosed is a method of inhibiting proliferation of cancer cells by contacting cancer cells with a powder from apple peel under conditions effective to inhibit proliferation of the cancer cells.
대표청구항
▼
1. A powder obtained from apple peel that has been subjected to phytochemical preservation wherein the powder has a phenolic content and a flavonoid content similar to fresh apple peel on a fresh weight basis, wherein the powder has a water activity of less than 0.30 and the phenolic content of the
1. A powder obtained from apple peel that has been subjected to phytochemical preservation wherein the powder has a phenolic content and a flavonoid content similar to fresh apple peel on a fresh weight basis, wherein the powder has a water activity of less than 0.30 and the phenolic content of the powder is at least about 92% of the phenolic content of fresh apple peel. 2. The powder according to claim 1, wherein the powder comprises flavonoids in a concentration of about 250-450 mg catechin equivalents per 100 grams of fresh apple peel. 3. The powder according to claim 1, wherein the powder comprises anthocyanins in a concentration of about 1-50 mg cyanidin 3-glucoside equivalents per 100 grams of fresh apple peel. 4. The powder according to claim 1, wherein the powder has an antioxidant activity of about 200-300μmol vitamin C equivalents per 1 gram of fresh apple peel. 5. The powder according to claim 1, wherein the powder has antiproliferative activity with a median effective dose EC50 of about 9-15 mg fresh apple peel/mL. 6. A capsule comprising the powder according to claim 1. 7. A tablet comprising the powder according to claim 1 in compressed form. 8. A foodstuff comprising the powder according to claim 1. 9. The foodstuff according to claim 8, wherein the foodstuff is selected from the group consisting of sauce, tea, candy, cereals, breads, fruit mixes, fruit salads, salads, snack bars, fruit leather, health bars, granola, smoothies, soups, juices, cakes, pies, shakes, ice cream, and health drinks.
이 특허에 인용된 특허 (10)
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Glass Richard W. (College Station TX) Koerner Dennis W. (Bedford TX), Crisp apple snack and process for making same.
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Jakobsson Maja (Alnarp SEX) Skjldebrand Christina (Gothenburg SEX) Sjholm Ingegerd (Alnarp SEX), Dehydrofreezing of peeled apple pieces.
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Sikora Paul Thomas,IEX ; Grocholski Wlodzimierz Ludwik, Dried product and a drying process.
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Haddad, William F.; Shure, Kenneth B.; Liu, Zhong, Food additives having enlarged concentration of phenolics extracted from fruits and vegetables and process of obtaining the same.
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Haddad, William F.; Kutty, Vinod; Shure, Kenneth B., Food additives having enlarged concentration of phenolics extracted from fruits, and process of obtaining the same.
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Johnston Ian F. (4001 Westerly Pl. ; Suite 106 Newport Beach CA 92660), Food from non-edible fruit by-products and method for production.
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Howard, Alan Norman; Nigdikar, Shaja Vijay; Rajput-Williams, Jayshri; Williams, Norman Ross, Food supplements containing polyphenols.
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Paufique, Jean-Jacques, Process for the extraction of an active principle from teguments of apple, active principle obtained, and composition for counteracting the consequences of oxidative stress of the skin.
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Tanabe Masayuki,JPX ; Kanda Tomomasa,JPX ; Yanagida Akio,JPX, Process for the production of fruit polyphenols from unripe rosaceae fruit.
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Nieuwenhuizen, Arie Gijsbert; Van Laere, Katrien Maria Jozefa, Reducing appetite in mammals by administering procyanidin and hydroxycitric acid.
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