IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0891428
(2010-09-27)
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등록번호 |
US-8571618
(2013-10-29)
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발명자
/ 주소 |
- Lamego, Marcelo
- Merritt, Sean
- Kiani, Massi Joe E.
|
출원인 / 주소 |
- Cercacor Laboratories, Inc.
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대리인 / 주소 |
Knobbe Martens Olson & Bear LLP
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인용정보 |
피인용 횟수 :
166 인용 특허 :
286 |
초록
▼
This disclosure describes, among other features, systems and methods for customizing calibration curves, parameter algorithms, and the like to individual users. An initial calibration curve generated based on a population can be used as a starting point in an algorithm for measuring a physiological
This disclosure describes, among other features, systems and methods for customizing calibration curves, parameter algorithms, and the like to individual users. An initial calibration curve generated based on a population can be used as a starting point in an algorithm for measuring a physiological parameter such as glucose. The measurement algorithm can determine one or more initial measurement values for a user based on the initial calibration curve. In certain embodiments, one or more alternative measurements, such as invasive or minimally invasive measurements, can periodically or sporadically be input into the measurement algorithm. The algorithm can use the alternative measurements to adapt the calibration curve to the individual. As a result, measurements for the individual can more accurately reflect the individual's actual parameter values.
대표청구항
▼
1. A device capable of producing a signal responsive to light attenuated by tissue at a measurement site, the device comprising: an optical sensor configured to emit light on tissue of a living person, detect the light after attenuation by the tissue, and output a signal responsive to the attenuated
1. A device capable of producing a signal responsive to light attenuated by tissue at a measurement site, the device comprising: an optical sensor configured to emit light on tissue of a living person, detect the light after attenuation by the tissue, and output a signal responsive to the attenuated light; anda processor configured to: receive the signal from the optical sensor;process the signal with a measurement algorithm to determine a first measurement of a physiological parameter, wherein the physiological parameter is glucose, and wherein the measurement algorithm comprises a plurality of basis functions and associated weights, wherein the measurement algorithm is configured to apply a combination of the basis functions and the weights to the signal to determine the first measurement,receive a second measurement of the physiological parameter from an alternative source, the second measurement being an invasive or minimally-invasive glucose measurement, andadaptively adjust the measurement algorithm based at least partly on the second measurement by adapting the weights of the measurement algorithm. 2. The device of claim 1, wherein the processor is further configured to adaptively adjust the measurement algorithm by adjusting a calibration curve associated with the measurement algorithm. 3. The device of claim 1, wherein the alternative source comprises an invasive measurement device. 4. The device of claim 1, wherein the alternative source comprises a minimally-invasive measurement device. 5. The device of claim 1, wherein the alternative source comprises a finger-prick device. 6. The device of claim 1, wherein the alternative source comprises an input of the second measurement provided by the living person. 7. A device capable of producing a signal responsive to light attenuated by tissue at a measurement site, the device comprising: a processor configured to: receive a signal from an optical sensor, the signal representing physiological information of a patient;process the signal with a measurement algorithm to determine a first measurement of a physiological parameter, wherein the physiological parameter is glucose, and wherein the measurement algorithm comprises a plurality of basis functions and associated weights, wherein the measurement algorithm is configured to apply a combination of the basis functions and the weights to the signal to determine the first measurement;receive a second measurement of the physiological parameter from an alternative source, the second measurement being an invasive or minimally-invasive glucose measurement; andadaptively adjust the measurement algorithm based at least partly on the second measurement by adapting the weights of the measurement algorithm. 8. The device of claim 7, wherein the processor is further configured to adaptively adjust the measurement algorithm by adjusting a calibration curve associated with the measurement algorithm. 9. The device of claim 7, wherein the alternative source comprises an invasive measurement device. 10. The device of claim 7, wherein the alternative source comprises a minimally-invasive measurement device. 11. The device of claim 7, wherein the alternative source comprises a finger-prick device. 12. The device of claim 7, wherein the alternative source comprises an input of the second measurement provided by the patient. 13. A method of producing a signal responsive to light attenuated by tissue at a measurement site, the method comprising: receiving a signal from an optical sensor, the signal representing physiological information of a patient;processing the signal with a measurement algorithm, by one or more processors, to determine a first measurement of a physiological parameter, wherein the physiological parameter is glucose, and wherein the measurement algorithm comprises a plurality of basis functions and associated weights, wherein the measurement algorithm is configured to apply a combination of the basis functions and the weights to the signal to determine the first measurement;receiving a second measurement of the physiological parameter from an alternative source, the second measurement being an invasive or minimally-invasive glucose measurement; andadaptively adjusting the measurement algorithm based at least partly on the second measurement by adapting the weights of the measurement algorithm. 14. The method of claim 13, wherein the processor is further configured to adaptively adjust the measurement algorithm by adjusting a calibration curve associated with the measurement algorithm. 15. The method of claim 13, wherein the alternative source comprises an invasive measurement device. 16. The method of claim 13, wherein the alternative source comprises a minimally-invasive measurement device. 17. The method of claim 13, wherein the alternative source comprises a finger-prick device. 18. The method of claim 13, wherein the alternative source comprises an input of the second measurement provided by the patient.
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