초록

Stabilized cationic ammonium compounds are described. The compounds are stabilized with pyridine-based chelators and/or heteroketo-based chelators that impede the generation of nitrogen comprising groups from the cationic ammonium compounds.

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1. A composition comprising a cationic ammonium compound and a pyridine-based chelator, a heteroketo-based chelator, or both, the chelator being one which impedes the generation of a nitrogen comprising group from the cationic ammonium compound within the composition wherein the nitrogen comprising

1. A composition comprising a cationic ammonium compound and a pyridine-based chelator, a heteroketo-based chelator, or both, the chelator being one which impedes the generation of a nitrogen comprising group from the cationic ammonium compound within the composition wherein the nitrogen comprising group comprises a trimonium group. 2. A composition comprising a cationic ammonium compounds having the formula: wherein q, t and v are each independently 0 or 1 with the proviso that the sum of q, t and v is equal to 1, each R is independently hydrogen, C1-12 alkyl, C1-12 hydroxy alkyl or where q′, t′ and v′ are each independently 0 or 1 with the proviso that the sum of q′, t′ and v′ is equal to 1, each R1 is independently a hydrogen, C1-12 alkyl, or a C1-12 hydroxy alkyl, each R2 is independently hydrogen, C1-3 alkyl, monosaccharyl, oligosaccharyl or polysaccharyl, each n is independently an integer from 1 to about 12, r is an integer from 0 to about 5, X− is an anionic counterion, the cationic ammonium compound being stabilized with a chelator, comprising pyridine-based chelator, heteroketo-based chelator or both. 3. The composition according to claim 2 wherein the anionic counterion is organic or inorganic. 4. The composition according to claim 2 wherein the chelator comprises groups represented by the formulae wherein: each R3 is independently N or O and each u is 0 or 1 with the proviso that u is not 1 when R3 is O;each R4 is independently H, OH, NH2, NO2,  where D isH or a cation selected from the group consisting of Na, K, Li, Ca, Mg or N(R8)4 where each R8 is independently H or a C1-3 alkyl;each R5 is independently  where each Z independently H, C1-3 alkyl N(R8)2, OD, arylor where each Y in independently H, OH, a C1-6 alkyl or aryl, and each Z1 is independentlyO or N—Y;R6 is O or N—Y; andR7 is H or a C1-6 alkyl. 5. The composition according to claim 2 wherein the cationic ammonium compound is a salt of hydroxypropyltri (C1-C3 alkyl) ammonium mono-substituted-saccharide, salts of hydroxypropyltri (C1-C3 alkyl) ammonium mono-substituted polyols, dihydroxypropyltri (C1-C3 alkyl) ammonium salts, dihydroxypropyldi (C1-C3 alkyl) mono(hydroxyethyl) ammonium salts, guar hydroxypropyl trimonium salts, 2,3-dihydroxypropyl tri(C1-C3 alkyl or hydroxalkyl) ammonium salts or mixtures thereof. 6. The composition according to claim 2 wherein the cationic ammonium compound is 1,2-dihydroxypropyltrimonium chloride. 7. A composition comprising: (a) (b) a cosmetically acceptable carrier; and(c) a preservative wherein q, t and v are each independently 0 or 1 with the proviso that the sum of q, t and v is equal to 1, each R is independently hydrogen, C1-12 alkyl, C1-12hydroxy alkyl or where q′, t′ and v′ are each independently 0 or 1 with the proviso that the sum of q′, t′ and v′ is equal to 1, each R1 is independently a hydrogen, C1-12 alkyl, or a C1-12 hydroxy alkyl, each R2 is independently hydrogen, C1-3 alkyl, monosaccharyl, oligosaccharyl or polysaccharyl, each n is independently an integer from 1 to about 12, r is an integer from 0 to about 5, X− is an anionic counterion, the cationic ammonium compound being stabilized with a chelator comprising pyridine-based chelator, heteroketo-based chelator, or both. 8. The composition according to claim 7 wherein the composition is topically applied to the body. 9. The composition according to claim 8 wherein the composition is a leave-on or rinse off composition. 10. The composition according to claim 9 wherein the composition is a moisturizing composition. 11. The composition according to claim 9 wherein the cationic ammonium compound is a salt of a hydroxypropyltri (C1-C3 alkyl) ammonium mono-substituted saccharide, salts of hydroxypropyltri (C1-C3 alkyl) ammonium mono-substituted polyols, dihydroxypropyltri (C1-C3 alkyl) ammonium salts, dihydroxypropyldi (C1-C3 alkyl) mono(hydroxyethyl) ammonium salts, guar hydroxypropyl trimonium salts, 2,3-dihydroxypropyl tri(C1-C3 alkyl or hydroxalkyl) ammonium salts or mixtures thereof. 12. The composition according to claim 8 wherein the cationic ammonium compound is 1,2-dihydroxypropyltrimonium chloride. 13. The composition according to claim 9 wherein the composition comprises from about 0.02 to about 30% by weight cationic ammonium compound and from about 0.01 to about 7% by weight chelator. 14. The composition according to claim 9 wherein the chelator comprises groups represented by the formulae wherein: each R3 is independently N or O and each u is 0 or 1 with the proviso that u is not 1 when R3 is O;each R4 is independently H, OH, NH2, NO2,  where D isH or a cation selected from the group consisting of Na, K, Li, Ca, Mg or N(R8)4 where each R8 is independently H or a C1-3 alkyl;each R5 is independently  were each Z independently H, C1-3 alkyl N(R8)2, OD, arylor where each Y in independently H, OH, a C1-6 alkyl or aryl, and each Z1 is independentlyO or N—Y:R6 is O or N—Y; andR7 is H or a C1-6 alkyl. 15. The composition according to claim 9 wherein the chelator is chelidamic acid. 16. The composition according to claim 9 wherein the composition further comprises a humectant. 17. The composition according to claim 9 wherein the composition further comprises a substituted urea. 18. The composition according to claim 16 wherein the humectant is glycerine. 19. A method for stabilizing a cationic ammonium compound comprising the steps of: a) contacting the cationic ammonium compound with a pyridine-based chelator and/or a heteroketo-based chelator; andb) impeding the formation of a nitrogen comprising groupwherein the nitrogen comprising group comprises a trimonium group.