IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0539065
(2003-12-18)
|
등록번호 |
US-8591812
(2013-11-26)
|
우선권정보 |
SE-0203772 (2002-12-19) |
국제출원번호 |
PCT/SE03/02001
(2003-12-18)
|
§371/§102 date |
20050615
(20050615)
|
국제공개번호 |
WO2004/057319
(2004-07-08)
|
발명자
/ 주소 |
- Aastrup, Teodor
- Smith, Jan
- Anderson, Henrik
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
0 인용 특허 :
8 |
초록
▼
A piezoelectric sensor arrangement for analysis of fluid samples includes a signal source, a measuring device and a docking system. The sensor arrangement comprises a first part capable of receiving a sensor element that exposes a piezoelectric quartz crystal, a second part comprising fluid channels
A piezoelectric sensor arrangement for analysis of fluid samples includes a signal source, a measuring device and a docking system. The sensor arrangement comprises a first part capable of receiving a sensor element that exposes a piezoelectric quartz crystal, a second part comprising fluid channels for the sample and a flow cell element, which preferably is removable and which comprises a recess, and inlet and outlet fluid channels for leading a fluid through the recess. The first and second parts are movable in relation to each other between a closed position and an open position and are arranged such that in the closed position the recess of the flow cell element is sealingly covered by the piezoelectric quartz crystal so that a flow cell is formed by the flow cell element and the quartz crystal.
대표청구항
▼
1. A piezoelectric sensor arrangement for analysis of at least one liquid sample, comprising: a signal source;a measuring device; anda docking system comprising a first part and a second part, wherein said first part comprises means for receiving a sensor element which sensor element comprises a pie
1. A piezoelectric sensor arrangement for analysis of at least one liquid sample, comprising: a signal source;a measuring device; anda docking system comprising a first part and a second part, wherein said first part comprises means for receiving a sensor element which sensor element comprises a piezoelectric quartz crystal having a freely accessible electrode and which electrode is positioned to contact the liquid sample when in use, said means for receiving comprising an opening allowing said sensor element to contact a flow cell element when in use;said second part comprises liquid sample channels to conduct the sample and a flow cell element;said flow cell element comprises an abutting part provided with an outwardly open recess surrounded by an abutting surface, inlet liquid sample channels, and outlet liquid sample channels;said inlet fluid channels and said outlet liquid sample channels are configured to lead the liquid sample through said recess;said abutting surface and a portion of said abutting part closest to said abutting surface are made of an elastic material;said elastic material is capable of forming a seal against the surface of the piezoelectric quartz crystal;said first and second part are movable in relation to each other between a closed position and an open position;when said first and second parts are moved from said open position to said closed position an upper surface of said abutting part of said flow cell element comes into abutment with said piezoelectric quartz crystal; andwhen said first and second parts are in said closed position a seal forms between said piezoelectric quartz crystal and said recess of said flow cell element to create a flow cell. 2. A sensor arrangement according to claim 1, wherein the flow cell element is removable. 3. A sensor arrangement according to claim 1, wherein said elastic material has a hardness of 10-95° Shore. 4. A sensor arrangement according to claim 3, wherein said elastic material has a hardness of 45-95° Shore. 5. A sensor arrangement according to claim 1, wherein the first part is arranged to move slidably with relation to the second part, so that the quartz crystal comes into abutment with the flow cell element in the second part. 6. A sensor arrangement according to claim 1, wherein the first part is guided between said closed and open positions by means of guide rods. 7. A sensor arrangement according to claim 1, wherein the first part is guided along a linear path. 8. A sensor arrangement according to claim 1, wherein the means for receiving the sensor element has a cavity provided with a slot, through which the sensor element can be inserted and an opening through which the crystal of the sensor element can come into contact with the flow cell element. 9. A sensor arrangement according to claim 1, wherein the second part comprises a sample providing part that has a recess in which the flow cell element is arranged and an operating part that includes means for movement of said first part. 10. A sensor arrangement according to claim 9, wherein the means for movement of said first part includes a screw which is connected by thread engagement to the first part and which is operated by a handle. 11. A sensor arrangement according to claim 1, wherein the second part is provided with electrical contacts for connection with electrical contact areas on the sensor element. 12. A sensor arrangement according to claim 11, wherein the electrical contacts are spring loaded contacting pins. 13. A sensor arrangement according to claim 11, wherein the electrical contacts are arranged on a sample providing part. 14. A sensor arrangement according to claim 1, wherein the recess of the flow cell element has a shape that corresponds to the shape of the first electrode. 15. A flow cell element for use in the piezoelectric sensor arrangement of claim 1, comprising: an abutting part comprising an outwardly open recess, inlet liquid sample channels, and outlet liquid sample channels, wherein said inlet liquid sample channels and said outlet liquid sample channels lead the liquid sample through said recess;said recess is surrounded by an abutting surface;said abutting surface and a portion of the abutting part closest to the abutting surface is made of an elastic material;said abutting surface is adapted to come into direct abutment with the surface of the piezoelectric quartz crystal in a sensor element, so as to form a flow cell together with the sensor element, by being sealingly covered by the crystal, when the first and second parts of the piezoelectric sensor arrangement are moved from an open position to a closed position,wherein the inlet and outlet liquid sample channels are arranged closer to the periphery of the recess than to the center of the recess and diametrically opposed to each other,wherein the abutting surface that surrounds the recess comprises a ridge having a smooth upper surface; the recess has a bottom, and said bottom of the recess is a flat surface, andwherein the flow cell element is formed from one piece of elastic material. 16. A flow cell element according to claim 15, wherein said elastic material has a hardness of 10-95° Shore. 17. A flow cell element according to claim 16, wherein said elastic material has a hardness of 45-95° Shore. 18. A flow cell element according to claim 15, wherein the ridge has a width of 0.05-1 mm. 19. A flow cell element according to claim 15, wherein the recess has a depth of 0.01-0.5 mm. 20. A flow cell element according to claim 15, wherein the elastic material is selected from the group consisting of polyurethane, silicone and PDMS. 21. A flow cell element according to claim 15, wherein the recess has a depth of 0.05-0.2 mm. 22. A flow cell element according to claim 15, wherein the recess has extensions in which the inlet and outlet liquid sample channels are arranged. 23. A flow cell element for use in the piezoelectric sensor arrangement of claim 1, comprising: an abutting part comprising an outwardly open recess, inlet liquid sample channels, and outlet liquid sample channels, wherein said inlet liquid sample channels and said outlet liquid sample channels lead the liquid sample through said recess;said recess is surrounded by an abutting surface;said abutting surface and a portion of the abutting part closest to the abutting surface is made of an elastic material;said abutting surface is adapted to come into direct abutment with the surface of the piezoelectric quartz crystal in a sensor element, so as to form a flow cell together with the sensor element, by being sealingly covered by the crystal, when the first and second parts of the piezoelectric sensor arrangement are moved from an open position to a closed position,wherein the abutting surface is constituted by a ridge that has a smooth upper surface, the inner edge of the ridge forming the periphery of the recess,wherein the recess has a bottom, and said bottom is a flat surface, andwherein the flow cell element is formed from one piece of elastic material.
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