Techniques for determining morphological stability of cardiac cycles
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/04
A61N-001/00
출원번호
US-0104794
(2011-05-10)
등록번호
US-8594775
(2013-11-26)
발명자
/ 주소
Ghosh, Subham
Gillberg, Jeffrey M.
출원인 / 주소
Medtronic, Inc.
대리인 / 주소
Soldner, Michael C.
인용정보
피인용 횟수 :
9인용 특허 :
1
초록▼
A method includes retrieving electrogram (EGM) data for N cardiac cycles from a memory of an implantable medical device. N is an integer greater than 1. The method further include categorizing each of the N cardiac cycles into one of a plurality of categories based on a morphology of the N cardiac c
A method includes retrieving electrogram (EGM) data for N cardiac cycles from a memory of an implantable medical device. N is an integer greater than 1. The method further include categorizing each of the N cardiac cycles into one of a plurality of categories based on a morphology of the N cardiac cycles and performing comparisons between pairs of the N cardiac cycles. Each of the comparisons between two cardiac cycles includes detecting a mismatch between the two cardiac cycles when the two cardiac cycles are in different categories, and detecting a match between the two cardiac cycles when the two cardiac cycles are in the same category. Additionally, the method includes classifying the rhythm of the N cardiac cycles based on a number of detected matches and detected mismatches.
대표청구항▼
1. A method comprising: retrieving electrogram (EGM) data for N cardiac cycles from a memory of an implantable medical device, wherein N is an integer greater than 1;categorizing each of the N cardiac cycles into one of a plurality of categories based on a morphology of the N cardiac cycles;performi
1. A method comprising: retrieving electrogram (EGM) data for N cardiac cycles from a memory of an implantable medical device, wherein N is an integer greater than 1;categorizing each of the N cardiac cycles into one of a plurality of categories based on a morphology of the N cardiac cycles;performing comparisons between pairs of the N cardiac cycles, each of the comparisons between two cardiac cycles including: detecting a mismatch between the two cardiac cycles when the two cardiac cycles are in different categories; anddetecting a match between the two cardiac cycles when the two cardiac cycles are in the same category; andclassifying the rhythm of the N cardiac cycles based on a number of detected matches and detected mismatches, wherein categorizing each of the N cardiac cycles comprises categorizing a single cardiac cycle of the N cardiac cycles based on at least one of a positive peak value of the single cardiac cycle, a negative peak value of the single cardiac cycle, and an order in which the positive peak value and the negative peak value occur in the single cardiac cycle, and further comprising:categorizing the single cardiac cycle as a dominantly positive cycle when the positive peak value is greater than the absolute value of the negative peak value by a first threshold amount; andcategorizing the single cardiac cycle as a dominantly negative cycle when the absolute value of the negative peak value is greater than the positive peak value by a second threshold amount. 2. The method of claim 1, wherein the implantable medical device includes at least one of a pacemaker and a cardioverter-defibrillator. 3. The method of claim 1, further comprising categorizing the single cardiac cycle as one of initially positive or initially negative when the positive peak value is not greater than the absolute value of the negative peak value by the first threshold amount and when the absolute value of the negative peak value is not greater than the positive peak value by the second threshold amount. 4. The method of claim 3, wherein categorizing the single cardiac cycle as initially positive comprises determining that the positive peak value occurs before the negative peak value in the single cardiac cycle, and wherein categorizing the single cardiac cycle as initially negative comprises determining that the negative peak value occurs before the positive peak value in the single cardiac cycle. 5. The method of claim 1, wherein performing comparisons between pairs of the N cardiac cycles comprises performing N*(N−1)/2 comparisons. 6. The method of claim 1, wherein classifying the rhythm comprises: classifying the rhythm as a monomorphic ventricular tachycardia when the number of detected matches is greater than or equal to a threshold number of matches; andclassifying the rhythm as at least one of a polymorphic ventricular tachycardia or ventricular fibrillation when the number of detected matches is less than the threshold number of matches. 7. The method of claim 1, wherein each of the comparisons between the two cardiac cycles includes detecting a match between the two cardiac cycles when the two cardiac cycles are in the same category and the two cardiac cycles have a second quantifiable morphological similarity. 8. The method of claim 7, wherein the second quantifiable morphological similarity is a peak-to-peak amplitude, and wherein each of the comparisons between the two cardiac cycles includes detecting a match between the two cardiac cycles when the two cardiac cycles are in the same category and when a difference in the peak-to-peak amplitudes of the two cardiac cycles is less than a threshold amplitude. 9. The method of claim 7, wherein the second quantifiable morphological similarity includes slope values of the two cardiac cycles, areas of the two cardiac cycles, and ratios of peak values of the two cardiac cycles. 10. The method of claim 1, wherein N is an integer greater than or equal to 12. 11. A medical device comprising: a memory; anda processing module configured to: retrieve electrogram (EGM) data for N cardiac cycles from the memory, wherein N is an integer greater than 1;categorize each of the N cardiac cycles into one of a plurality of categories based on a morphology of the N cardiac cycles;perform comparisons between pairs of the N cardiac cycles, each of the comparisons between two cardiac cycles including: detecting a mismatch between the two cardiac cycles when the two cardiac cycles are in different categories; anddetecting a match between the two cardiac cycles when the two cardiac cycles are in the same category; andclassify the rhythm of the N cardiac cycles based on a number of detected matches and detected mismatches, wherein the processing module is configured to categorize a single cardiac cycle of the N cardiac cycles based on at least one of a positive peak value of the single cardiac cycle, a negative peak value of the single cardiac cycle, and an order in which the positive peak value and the negative peak value occur in the single cardiac cycle, and wherein the processing module is configured to:categorize the single cardiac cycle as a dominantly positive cycle when the positive peak value is greater than the absolute value of the negative peak value by a first threshold amount; andcategorize the single cardiac cycle as a dominantly negative cycle when the absolute value of the negative peak value is greater than the positive peak value by a second threshold amount. 12. The medical device of claim 11, further comprising a housing configured to be implanted in a patient, wherein the housing houses the memory and the processing module. 13. The medical device of claim 11, wherein the processing module is configured to categorize the single cardiac cycle as one of initially positive or initially negative when the positive peak value is not greater than the absolute value of the negative peak value by the first threshold amount and when the absolute value of the negative peak value is not greater than the positive peak value by the second threshold amount. 14. The medical device of claim 13, wherein the processing module is configured to categorize the single cardiac cycle as initially positive when the positive peak value occurs before the negative peak value in the single cardiac cycle, and wherein the processing module is configured to categorize the single cardiac cycle as initially negative when the negative peak value occurs before the positive peak value in the single cardiac cycle. 15. The medical device of claim 11, wherein the processing module is configured to: classify the rhythm as a monomorphic ventricular tachycardia when the number of detected matches is greater than or equal to a threshold number of matches; andclassify the rhythm as one of a polymorphic ventricular tachycardia and ventricular fibrillation when the number of detected matches is less than the threshold number of matches. 16. The medical device of claim 11, wherein each of the comparisons between the two cardiac cycles includes detecting a match between the two cardiac cycles when the two cardiac cycles are in the same category and the two cardiac cycles have a second quantifiable morphological similarity. 17. The medical device of claim 16, wherein the second quantifiable morphological similarity is a peak-to-peak amplitude, and wherein each of the comparisons between the two cardiac cycles includes detecting a match between the two cardiac cycles when the two cardiac cycles are in the same category and when a difference in the peak-to-peak amplitudes of the two cardiac cycles is less than a threshold amplitude.
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