IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0711749
(2010-02-24)
|
등록번호 |
US-8608696
(2013-12-17)
|
발명자
/ 주소 |
- DiMeo, Andrew J.
- Cox, Nathan M.
- Grove, Steven P.
- Lee, Samuel
- Oltmans, Luke D.
- Sauer, Kathryn H.
|
출원인 / 주소 |
- North Carolina State University
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
1 인용 특허 :
97 |
초록
▼
A cooling device includes a target fluid inlet, a target fluid outlet, an inner conduit, and a chamber surrounding the inner conduit. The inner conduit communicates with the target fluid inlet and the target fluid outlet, and provides a flow path for a target fluid to be cooled. The chamber contains
A cooling device includes a target fluid inlet, a target fluid outlet, an inner conduit, and a chamber surrounding the inner conduit. The inner conduit communicates with the target fluid inlet and the target fluid outlet, and provides a flow path for a target fluid to be cooled. The chamber contains a first endothermic reactant and includes a reactant inlet selectively alterable from a closed state to an open state. When the reactant inlet is in the closed state, the first endothermic reactant is isolated from a second endothermic reactant and no endothermic reaction occurs. When the reactant inlet is in the open state, the reactant inlet provides a flow path for enabling the second endothermic reactant to come into contact with the first endothermic reactant in the chamber for initiating the endothermic reaction and cooling the target fluid in the inner conduit.
대표청구항
▼
1. A method for cooling a target fluid, the method comprising: flowing a target fluid from a target fluid inlet of a cooling device, through a plurality of inner conduits of the cooling device, and to a target fluid outlet of the cooling device; andwhile flowing the target fluid through the inner co
1. A method for cooling a target fluid, the method comprising: flowing a target fluid from a target fluid inlet of a cooling device, through a plurality of inner conduits of the cooling device, and to a target fluid outlet of the cooling device; andwhile flowing the target fluid through the inner conduits, removing heat from the target fluid by conducting an endothermic reaction in the cooling device, wherein conducting the endothermic reaction includes mixing a first endothermic reactant with a second endothermic reactant in a chamber of the cooling device surrounding, but physically isolated from, the inner conduits. 2. The method of claim 1, wherein: conducting the endothermic reaction further includes altering a reactant inlet of the cooling device from a closed state to an open state;in the closed state, the first endothermic reactant is isolated from the second endothermic reactant in the chamber and no endothermic reaction occurs; andin the open state, the reactant inlet provides a flow path for enabling the second endothermic reactant to come into contact with the first endothermic reactant in the chamber for initiating the endothermic reaction and cooling the target fluid in the inner conduit. 3. The method of claim 2, wherein altering the reactant inlet comprises placing an external source of the second endothermic reactant in fluid communication with the reactant inlet to establish a flow of the second endothermic reactant from the external source, through the reactant inlet and into the chamber. 4. The method of claim 2, wherein: the reactant inlet comprises a barrier, which in the closed state divides the chamber into a first region and a second region physically isolated from the first region;prior to altering the reactant inlet from the closed state to the open state, the first region contains the first endothermic reactant and the second region contains the second endothermic reactant; andaltering the reactant inlet comprises opening the barrier to establish fluid communication between the first region and the second region. 5. The method of claim 1, further comprising flowing cooled target fluid from the target fluid outlet to a patient. 6. The method of claim 1, wherein the target fluid comprises saline solution. 7. The method of claim 6, wherein the target fluid further comprises a therapeutically active drug. 8. The method of claim 1, further comprising cooling the target fluid to a temperature of about 3 to 4 degrees Celsius. 9. The cooling device of claim 1, wherein the first endothermic reactant comprises an inorganic salt. 10. The cooling device of claim 9, wherein the second endothermic reactant comprises water. 11. A method of treating a patient, the method comprising: flowing a target fluid to be cooled from a reservoir through a target fluid inlet of a cooling device, and into a plurality of inner conduits of the cooling device, the cooling device comprising a chamber surrounding the inner conduits and containing a first endothermic reactant, the chamber including a reactant inlet selectively alterable from a closed state to an open state, wherein in the closed state the first endothermic reactant is isolated from a second endothermic reactant and no endothermic reaction occurs;initiating the endothermic reaction and cooling the target fluid in the inner conduits by altering the reactant inlet from the closed state to the open state, wherein the reactant inlet provides a flow path for enabling the second endothermic reactant to come into contact with the first endothermic reactant in the chamber;flowing the cooled target fluid through a target fluid outlet of the cooling device into a cooled-fluid-receiving tube; andadministering to the patient the cooled target fluid in the cooled-fluid-receiving tube intravenously to reduce a core body temperature of the patient. 12. The method of claim 11, wherein the cooled target fluid is administered to the patient until the patient reaches a state of hypothermia. 13. The method of claim 11, wherein: the reactant inlet comprises a barrier, which in the closed state divides the chamber into a first region and a second region physically isolated from the first region;prior to altering the reactant inlet from the closed state to the open state, the first region contains the first endothermic reactant and the second region contains the second endothermic reactant; andaltering the reactant inlet comprises breaking the barrier to establish fluid communication between the first region and the second region.
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