Monitoring, analysis, and regulation of eating habits
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/04
A61B-005/103
A61B-005/117
A61N-001/00
출원번호
US-0573722
(2005-08-18)
등록번호
US-8612016
(2013-12-17)
국제출원번호
PCT/IL2005/000904
(2005-08-18)
§371/§102 date
20081218
(20081218)
국제공개번호
WO2006/018851
(2006-02-23)
발명자
/ 주소
Kliger, Anat
Policker, Shai
Aviv, Ricardo
출원인 / 주소
Metacure Limited
대리인 / 주소
Dippert, William H.
인용정보
피인용 횟수 :
3인용 특허 :
106
초록▼
Gastric apparatus is provided, including one or more sensors, adapted to generate respective sensor signals responsive to activity of a gastrointestinal tract of a subject. A control unit is configured with an eating detection threshold selected from the group consisting of: a predetermined threshol
Gastric apparatus is provided, including one or more sensors, adapted to generate respective sensor signals responsive to activity of a gastrointestinal tract of a subject. A control unit is configured with an eating detection threshold selected from the group consisting of: a predetermined threshold, and a threshold determined during a calibration procedure. The control unit is adapted to receive and analyze the sensor signals, and identify an aspect of at least one of the sensor signals indicative of periodic activity of the gastrointestinal tract. The control unit modifies the eating detection threshold responsive to identifying the aspect of the signals that is indicative of the periodic activity, and determines that an eating event has occurred responsive to the modified eating detection threshold and at least one of the analyzed sensor signals. Other embodiments are also described.
대표청구항▼
1. Gastric apparatus, comprising: one or more sensors, configured to generate respective sensor signals responsive to activity of a gastrointestinal tract of a subject; anda control unit, configured with an eating detection threshold selected from the group consisting of: a predetermined threshold,
1. Gastric apparatus, comprising: one or more sensors, configured to generate respective sensor signals responsive to activity of a gastrointestinal tract of a subject; anda control unit, configured with an eating detection threshold selected from the group consisting of: a predetermined threshold, and a threshold determined during a calibration procedure, and configured to: receive and analyze the sensor signals,identify an aspect of at least one of the sensor signals representing periodic activity of the gastrointestinal tract,modify the eating detection threshold responsive to identifying the aspect of the signals representing the periodic activity, anddetermine whether an eating event has occurred responsive to the modified eating detection threshold and at least one of the analyzed sensor signals,wherein the control unit is configured to modify the eating detection threshold responsive to identifying that the periodic activity is of a migrating motor complex (MMC). 2. The apparatus according to claim 1, wherein the control unit is configured to receive and analyze the sensor signals at a first time and a second time after the first time, and to modify the eating detection threshold responsive to a relationship between the sensor signals received at the first and the second times. 3. The apparatus according to claim 1, wherein the control unit is configured to identify the aspect representing the periodic activity which has a period of between 30 and 50 minutes. 4. The apparatus according to claim 1, wherein the one or more sensors comprise one or more implantable mechanical sensors. 5. The apparatus according to claim 1, wherein the one or more sensors comprise one or more implantable electrodes. 6. The apparatus according to claim 1, wherein the control unit is configured to identify the aspect representing the periodic activity which has a period of between 50 and 90 minutes. 7. The apparatus according to claim 1, wherein the control unit is configured to identify the aspect representing the periodic activity which has a period of between 90 and 120 minutes. 8. The apparatus according to claim 1, further comprising a set of one or more current-application electrodes, wherein the control unit is configured to drive the current-application electrodes to apply a current to tissue of the subject. 9. The apparatus according to claim 8, wherein the control unit is configured to drive the current-application electrodes to apply the current to the tissue in response to analysis of the eating event. 10. The apparatus according to claim 9, wherein the control unit is configured to drive the current-application electrodes to apply an ingestion control signal to the tissue in response to the analysis of the eating event. 11. The apparatus according to claim 10, wherein the control unit is configured to configure the ingestion-control signal to cause an effect in the subject selected from the group consisting of: a sensation of discomfort, a sensation of minor nausea, vertigo, pain, a contraction of the esophagus, a contraction of the lower esophageal sphincter, a feeling of satiation, and gastric dysrhythmia. 12. The apparatus according to claim 1, wherein the sensors are configured to be coupled to a stomach of the subject. 13. The apparatus according to claim 1, wherein the apparatus is configured to treat a condition of the subject. 14. The apparatus according to claim 13, wherein the apparatus is configured to treat obesity of the subject. 15. The apparatus according to claim 1, wherein the control unit is configured to apply a treatment to the subject in response to analysis of the eating event. 16. The apparatus according to claim 1, wherein the one or more sensors comprise at least two impedance sensors, which are configured to measure an electrical impedance between respective stomach sites, and wherein the eating detection threshold is an eating detection impedance threshold. 17. The apparatus according to claim 16, wherein the at least two impedance sensors are configured to measure the impedance between respective fundic sites, and wherein the eating detection impedance threshold is an eating detection fundic impedance threshold. 18. The apparatus according to claim 1, wherein the one or more sensors comprise at least one antral sensor, and wherein the control unit is configured to identify the aspect representing antral periodic electrical activity. 19. The apparatus according to claim 1, wherein the control unit is configured to determine that the eating event has occurred responsive to finding that a value of the at least one of the analyzed sensors signals crosses the modified eating detection threshold. 20. The apparatus according to claim 1, wherein the control unit is configured to determine a period of the periodic activity during a calibration period. 21. Gastric apparatus, comprising: one or more sensors, configured to generate respective sensor signals responsive to activity of a gastrointestinal tract of a subject; anda control unit, configured with an eating detection threshold selected from the group consisting of: a predetermined threshold, and a threshold determined during a calibration procedure, and configured to: receive and analyze the sensor signals,identify an aspect of at least one of the sensor signals representing periodic activity of the gastrointestinal tract,modify the eating detection threshold responsive to identifying the aspect of the signals representing the periodic activity, anddetermine whether an eating event has occurred responsive to the modified eating detection threshold and at least one of the analyzed sensor signals,wherein in modifying the eating detection threshold, the control unit is configured to modify the eating detection threshold in a threshold-modification direction, andwherein the control unit is configured, at a later time at least 30 minutes following modifying the eating detection threshold, to further modify the eating detection threshold in the threshold-modification direction responsive to identifying at the later time the aspect of the signals representing the periodic activity. 22. Gastric apparatus, comprising: one or more sensors, configured to generate respective sensor signals responsive to activity of a gastrointestinal tract of a subject; anda control unit, configured with an eating detection threshold selected from the group consisting of: a predetermined threshold, and a threshold determined during a calibration procedure, and configured to: receive and analyze the sensor signals,identify an aspect of at least one of the sensor signals representing periodic activity of the gastrointestinal tract,modify the eating detection threshold responsive to identifying the aspect of the signals representing the periodic activity, anddetermine whether an eating event has occurred responsive to the modified eating detection threshold and at least one of the analyzed sensor signals,wherein the control unit is configured, at a later time at least 30 minutes following modifying the eating detection threshold, to at least partially restore the eating detection threshold towards a previous value thereof, responsive to not identifying at the later time the aspect of the signals representing the periodic activity. 23. The apparatus according to claim 22, wherein the control unit is configured to modify the eating detection threshold responsive to identifying that the periodic activity is of a migrating motor complex (MMC). 24. Gastric apparatus, comprising: one or more sensors, configured to generate respective sensor signals responsive to activity of a gastrointestinal tract of a subject; anda control unit, configured with an eating detection threshold selected from the group consisting of: a predetermined threshold, and a threshold determined during a calibration procedure, and configured to: receive and analyze the sensor signals,identify an aspect of at least one of the sensor signals representing periodic activity of the gastrointestinal tract,modify the eating detection threshold responsive to identifying the aspect of the signals representing the periodic activity, anddetermine whether an eating event has occurred responsive to the modified eating detection threshold and at least one of the analyzed sensor signals,wherein the control unit is configured to receive and analyze the sensor signals at a first time and a second time after the first time, and to modify the eating detection threshold responsive to a relationship between the sensor signals received at the first and the second times, andwherein the control unit is configured to modify the eating detection threshold responsive to the relationship, wherein the first time is between 30 and 50 minutes prior to the second time. 25. The apparatus according to claim 24, wherein the control unit is configured to identify the sensor signals received at the first time as representing a migrating motor complex (MMC) and to identify the sensor signals received at the second time as representing a MMC, and to modify the eating detection threshold responsive to identifying the sensor signals received at the first and the second times as representing the MMC.
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