최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0267525 (2008-11-07) |
등록번호 | US-8626257 (2014-01-07) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 474 |
Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a
Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
1. A method for evaluating a change in a sensitivity of an analyte sensor over a predetermined time period, the method comprising: receiving sensor data from an analyte sensor, wherein the sensor data comprises one or more sensor analyte values measured in a biological sample of a host;intermittentl
1. A method for evaluating a change in a sensitivity of an analyte sensor over a predetermined time period, the method comprising: receiving sensor data from an analyte sensor, wherein the sensor data comprises one or more sensor analyte values measured in a biological sample of a host;intermittently calculating a sensitivity of the analyte sensor based at least in part on reference analyte data; andevaluating, using an electronic device, a change in sensitivity by evaluating a plurality of time-spaced sensitivity calculations over a predetermined time period, wherein evaluating a change in sensitivity is based at least in part on applying, throughout a sensor session, a priori sensitivity information, wherein the a priori sensitivity information comprises an expected profile that is a function of time. 2. The method of claim 1, wherein the predetermined time period is less than or equal to about 30 minutes. 3. The method of claim 2, wherein the predetermined time period is less than or equal to about 20 minutes. 4. The method of claim 3, wherein the predetermined time period is less than or equal to about 10 minutes. 5. The method of claim 2, wherein evaluating a change in sensitivity comprises evaluating at least two sensitivity measurements during the predetermined time period. 6. The method of claim 5, further comprising averaging and/or filtering the at least two sensitivity measurements prior to evaluating the at least two sensitivity measurements. 7. The method of claim 2, wherein evaluating a change in sensitivity comprises comparing the change in sensitivity with one or more criteria. 8. The method of claim 7, further comprising using a most recent sensitivity calculation evaluated to calibrate the analyte sensor when the change in sensitivity meets the one or more criteria. 9. The method of claim 7, further comprising not using a most recent sensitivity calculation evaluated to calibrate the analyte sensor when the change in sensitivity does not meet the one or more criteria. 10. The method of claim 2, wherein intermittently calculating a sensitivity of the analyte sensor comprises intermittently receiving a reference analyte value. 11. The method of claim 2, wherein intermittently receiving a reference analyte value comprises periodically receiving a measured analyte concentration from a reference analyte solution. 12. The method of claim 2, wherein intermittently receiving a reference analyte value comprises receiving a reference analyte value obtained from an in vitro analyte monitor. 13. The method of claim 2, wherein evaluating a change in sensitivity is iteratively performed on the plurality of time-spaced sensitivity calculations over the predetermined time period. 14. The method of claim 1, wherein the predetermined time period is at least about 30 minutes. 15. The method of claim 14, wherein the predetermined time period is at least about 60 minutes. 16. The method of claim 14, wherein the predetermined time period is at least about 120 minutes. 17. The method of claim 14, wherein evaluating a sensitivity is iteratively performed on the plurality of time-spaced sensitivity calculations over the predetermined time period. 18. The method of claim 14, wherein evaluating a sensitivity comprises evaluating all sensitivity calculations over a sensor session. 19. The method of claim 1, wherein the a priori sensitivity information defines a range of acceptable change in sensitivity. 20. The method of claim 1, wherein the analyte sensor comprises a first working electrode and a second working electrode, wherein the first working electrode is configured to provide a first signal comprising an analyte component and a baseline component and wherein the second working electrode is configured to provide a second signal comprising a baseline component without an analyte component. 21. The method of claim 20, wherein intermittently calculating a sensitivity of the analyte sensor is based at least in part on the first signal. 22. The method of claim 20, wherein intermittently calculating a sensitivity of the analyte sensor is based at least in part on the second signal. 23. The method of claim 20, further comprising subtracting the second signal from the first signal to obtain a subtracted signal, wherein intermittently calculating a sensitivity of the analyte sensor is based at least in part on the subtracted signal. 24. The method of claim 1, wherein the analyte sensor is intermittently exposed to a biological sample and to a reference solution. 25. The method of claim 24, wherein intermittently calculating a sensitivity of the analyte sensor is based at least in part on a signal obtained when the analyte sensor is exposed to a biological sample. 26. The method of claim 24, wherein intermittently calculating a sensitivity of the analyte sensor is based at least in part on a signal obtained when the analyte sensor is exposed to a reference solution. 27. The method of claim 24, wherein intermittently calculating a sensitivity of the analyte sensor is based at least in part on a signal obtained when the analyte sensor is exposed to a biological sample and a signal obtained when the analyte sensor is exposed to a reference solution. 28. The method of claim 1, further comprising drawing blood to the analyte sensor by using a flow control device.
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