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다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0771783 (2010-04-30) |
등록번호 | US-8649871 (2014-02-11) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 4 인용 특허 : 319 |
Methods, systems, and apparatus for quantifying the quality of a fiducial time marker for a candidate heart beat, quantifying the quality of a candidate heart beat, or determining a time of beat sequence of the patient's heart. A fiducial time marker is obtained for a candidate heart beat. A quality
Methods, systems, and apparatus for quantifying the quality of a fiducial time marker for a candidate heart beat, quantifying the quality of a candidate heart beat, or determining a time of beat sequence of the patient's heart. A fiducial time marker is obtained for a candidate heart beat. A quality index of said candidate heart beat is set to a first value. The candidate heart beat is tested with at least one beat validity test. At least a second value is added to said quality index of said candidate heart beat if said candidate heart beat passes said at least one beat validity test. The candidate heart beat is tested with at least a second heart beat validity test. At least a third value is added to said quality index of said candidate heart beat if said candidate heart beat passes said at least second heart beat validity test. In one class of beat validity test, a constraint defining a pass is modified at one or more times after the most recent prior valid heart beat that is greater than a constraint modification time threshold.
1. A non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform a method for determining a time of beat sequence of the patient's heart, comprising: obtaining a time series of fiducial time markers for candidate heart beats;identifying
1. A non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform a method for determining a time of beat sequence of the patient's heart, comprising: obtaining a time series of fiducial time markers for candidate heart beats;identifying valid heart beats from said candidate heart beats by subjecting a plurality of said candidate heart beats to at least one beat validity test, said at least one beat validity test comprising at least one interbeat interval test applied to a candidate heart beat interval derived from a candidate heart beat and at least one prior heart beat;accepting as valid heart beats the candidate heart beats that pass said at least one beat validity test, wherein a constraint defining said pass is modified after a time period since the most recent prior valid heart beat greater than a constraint modification time threshold; andperforming at least one responsive action based upon at least one said valid heart beat, the responsive action selected from the group consisting ofissuing a detection for an epileptic seizure event;delivering a neurostimulation therapy to the patient to treat an epileptic seizure event;warning at least one of a caregiver, the patient, or a physician; andlogging said modified constraint to a memory. 2. The non-transitory computer readable program storage unit of claim 1, wherein delivering a neurostimulation therapy comprises one of initiating a programmed neurostimulation therapy; andmodifying a programmed neurostimulation therapy to obtain a second neurostimulation therapy and applying said second neurostimulation therapy to a target neural structure. 3. The non-transitory computer readable program storage unit of claim 1, wherein the constraint is modified by relaxing said constraint by from about 1% to about 50%. 4. The non-transitory computer readable program storage unit of claim 1, wherein the constraint is modified by relaxing said constraint by greater than about 50%. 5. The non-transitory computer readable program storage unit of claim 1, wherein the constraint is modified by tightening said constraint by greater than about 1%. 6. The non-transitory computer readable program storage unit of claim 1, wherein the constraint is modified once after the constraint modification time threshold is passed. 7. The non-transitory computer readable program storage unit of claim 1, wherein the constraint is modified at a plurality of times after the constraint modification time threshold is passed. 8. The non-transitory computer readable program storage unit of claim 1, wherein the constraint is modified according to a step function at one or more times after the constraint modification time threshold is passed. 9. The non-transitory computer readable program storage unit of claim 1, wherein the constraint is modified according to a linear function over a range of times after the constraint modification time threshold is passed. 10. The non-transitory computer readable program storage unit of claim 1, wherein the constraint is modified according to a non-linear function over a range of times after the constraint modification time threshold is passed. 11. The non-transitory computer readable program storage unit of claim 1, wherein the constraint is modified to no more than a finite maximum value or no less than a finite minimum value. 12. A medical device, comprising: a sensor adapted to detect a candidate heart beat;a cardiac data collection module operatively coupled to said sensor, said cardiac data collection module adapted to obtain a time series of fiducial time markers for candidate heart beats; anda constraint-modifying heart beat validation module operatively coupled to said sensor and said cardiac data collection module, said constraint-modifying heart beat validation module adapted to identify valid heart beats from said candidate heart beats by subjecting a plurality of said candidate heart beats to at least one beat validity test, said at least one beat validity test comprising determining a candidate heart beat interval based on a candidate heart beat and at least one prior heart beat, said at least one beat validity test further comprising at least one interbeat interval test applied to said candidate heart beat, and accepting as valid heart beats the candidate heart beats that pass said at least one beat validity test, wherein a constraint defining said pass is modified after a time period since the most recent prior valid heart beat greater than a constraint modification time threshold; andat least one responsive action module adapted to perform at least one action based upon at least one said valid heart beat, the responsive action module selected from the group consisting ofa seizure detection module;a neurostimulation delivery module;a warning module; anda modified constraint logging module. 13. The medical device of claim 12, wherein the responsive action module is a seizure detection module. 14. A method for determining a time of beat sequence of the patient's heart, comprising: obtaining a time series of fiducial time markers for candidate heart beats;identifying valid heart beats from said candidate heart beats by subjecting a plurality of said candidate heart beats to at least one beat validity test, said at least one beat validity test comprising at least one interbeat interval test applied to a candidate heart beat interval derived from a candidate heart beat and at least one prior heart beat;accepting as valid heart beats the candidate heart beats that pass said at least one beat validity test, wherein a constraint defining said pass is modified after a time period since the most recent prior valid heart beat greater than a constraint modification time threshold; andperforming at least one responsive action based upon at least one said valid heart beat, the responsive action selected from the group consisting ofissuing a detection for an epileptic seizure event;delivering a neurostimulation therapy to the patient to treat an epileptic seizure event;warning at least one of a caregiver, the patient, or a physician; andlogging said modified constraint to a memory. 15. The method of claim 14, wherein delivering a neurostimulation therapy comprises one of initiating a programmed neurostimulation therapy; andmodifying a programmed neurostimulation therapy to obtain a second neurostimulation therapy and applying said second neurostimulation therapy to a target neural structure. 16. The method of claim 14, wherein the constraint is modified once after the constraint modification time threshold is passed. 17. The method of claim 14, wherein the constraint is modified according to a linear function over a range of times after the constraint modification time threshold is passed. 18. The method of claim 14, wherein the constraint is modified to no more than a finite maximum value or no less than a finite minimum value.
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