[특허]Clotting cascade initiating apparatus and methods of use and methods of closing wounds

Clotting cascade initiating apparatus and methods of use and methods of closing wounds 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61B-017/08 A61D-001/00 A61K-035/14
출원번호	US-0852094 (2013-03-28)
등록번호	US-8652169 (2014-02-18)
발명자 / 주소	Nowakowski, Karol L
출원인 / 주소	Closys Corporation
대리인 / 주소	Sara, Esq., Charles S.
인용정보	피인용 횟수 : 0 인용 특허 : 82

초록 ▼

Wound closure methods and apparatuses are provided which utilize blood fluid by activating the clotting cascade of the blood fluid outside the body within a substantially enclosed sterile container then introducing coagulated blood to the wound site. Methods and apparatuses for providing ways of inhibiting anticoagulants and slowing fibrin clot degradation are also disclosed. Kits for practicing the invention singularly or in combination with and/or associated with preferred procedures are also disclosed.

대표청구항 ▼

1. A method of treating a wound on a blood vessel of a patient using an apparatus comprising: collecting whole blood from the patient into a sterile containment chamber of the apparatus;exposing the whole blood to a procoagulant in the containment chamber to generate autologous clotted blood;transferring at least a portion of the autologous clotted blood through an opening of the apparatus placed proximate the wound to subcutaneously deliver the at least the portion of the autologous clotted blood proximate the wound. 2. The method of claim 1 wherein the collecting comprises collecting the whole blood from the wound on the blood vessel via the opening of the apparatus. 3. The method of claim 2 further comprising: establishing fluid communication between the apparatus and the blood vessel via the opening; andverifying the fluid communication. 4. The method of claim 3 wherein the verifying the fluid communication comprises collecting whole blood within a lumen distinct from the containment chamber. 5. The method of claim 4 wherein the verifying comprises visualization of at least a portion of the whole blood collected within the lumen. 6. The method of claim 1 wherein the procoagulant is predisposed within the apparatus. 7. The method of claim 1 wherein the procoagulant is predisposed within the containment chamber. 8. The method of claim 1 wherein the procoagulant comprises a porous matrix. 9. The method of claim 1 wherein the procoagulant comprises a porous matrix selected from the group consisting of cotton and diatomaceous earth. 10. The method of claim 1 wherein the procoagulant comprises glass. 11. The method of claim 1 wherein the procoagulant comprises a synthetic polymer. 12. The method of claim 11 wherein the synthetic polymer is selected from the group consisting of dacron, silicone, polyurethane, polycarbonate, polyethylene, polyvinylchloride, polypropylene, and nylon. 13. The method of claim 1 wherein the procoagulant comprises thrombin, collagen, fibrin, and fibrinogen. 14. The method of claim 1 wherein the procoagulant comprises heat. 15. The method of claim 1 wherein the procoagulant comprises aminocaproic acid. 16. The method of claim 1 wherein the whole blood contains an anticoagulant. 17. The method of claim 1 further comprising treating the whole blood with an anticoagulant inhibitor. 18. The method of claim 17 wherein the anticoagulant inhibitor is an agent capable of binding an anticoagulant. 19. The method of claim 18 wherein the anticoagulant inhibitor comprises diethylaminoethyl cellulose. 20. The method of claim 1 further comprising treating the whole blood with an anticlot inhibitor.

이 특허에 인용된 특허 (82)

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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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연합인증

Clotting cascade initiating apparatus and methods of use and methods of closing wounds 원문보기

초록 ▼

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Clotting cascade initiating apparatus and methods of use and methods of closing wounds 원문보기

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대표청구항 ▼

연구과제 타임라인

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