IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0317495
(2005-12-22)
|
등록번호 |
US-8663311
(2014-03-04)
|
발명자
/ 주소 |
- Besselink, Petrus Antonius
- Yribarren, Travis
- Von Oepen, Randolf
|
출원인 / 주소 |
|
대리인 / 주소 |
Novak Druce Connolly Bove + Quigg LLP
|
인용정보 |
피인용 횟수 :
2 인용 특허 :
67 |
초록
▼
Expandable biodegradable devices formed of bistable and multistable unit cells for use in devices, such as stents and graft systems, are provided, in which the device has two or more stable configurations, including a contracted configuration and an expanded configuration, the contracted stable conf
Expandable biodegradable devices formed of bistable and multistable unit cells for use in devices, such as stents and graft systems, are provided, in which the device has two or more stable configurations, including a contracted configuration and an expanded configuration, the contracted stable configuration having a smaller diameter than the expanded configuration.
대표청구항
▼
1. An expandable support device comprising: an expandable tube formed of a plurality of unit cells, each unit cell having a length, at least one unit cell of said plurality of unit cells having a stable contracted configuration and a stable expanded configuration, said at least one unit cell compris
1. An expandable support device comprising: an expandable tube formed of a plurality of unit cells, each unit cell having a length, at least one unit cell of said plurality of unit cells having a stable contracted configuration and a stable expanded configuration, said at least one unit cell comprising a rigid segment extending the length of said unit cell, anda flexible segment extending the length of said unit cell, the flexible segment being more flexible than the rigid segment such that when said unit cell is forcibly expanded in a radially outward direction from the stable contracted configuration toward the stable expanded configuration, said unit cell passes a transition point between the stable contracted configuration and the stable expanded configuration, and once said unit cell passes the transition point, the difference in flexibility between the flexible segment and the rigid segment causes the unit cell to automatically move further toward the expanded configuration. 2. The device of claim 1, wherein the expandable tube comprises a biodegradable material selected from the group consisting of: poly(L-lactide-coglycolide), polyhydroxyalkanoate, polyester amide, a chitosan and genipin structure and a silicon and iron composite. 3. The device of claim 1, wherein the rigid segment is coupled to the flexible segment. 4. The device of claim 1, wherein the flexible segment undergoes rotational motion during expansion. 5. The device of claim 1, wherein the flexible segment is arcuate prior to expansion of the unit cell. 6. The device of claim 1, wherein the plurality of unit cells define a wall having a plurality of slots therethrough with at least a portion of the plurality of slots having a wave-like shape when the device is in the stable contracted configuration. 7. The device of claim 6, wherein the wave-like shape transitions to an expanded wave-like shape when the device is expanded. 8. The device of claim 1, further comprising a tubular sleeve mounted on the plurality of unit cells. 9. The device of claim 8, wherein the tubular sleeve comprises a drug or bioactive agent. 10. The device of claim 1, wherein the flexible segment has a smaller cross-section than the rigid segment. 11. The device of claim 10, wherein the rigid segment remains unflexed during transition of the flexible segment from the stable contracted configuration to the stable expanded configuration. 12. The device of claim 1, wherein the flexible segment is coupled to the rigid segment by plastic hinges. 13. The device of claim 1, wherein the flexible segment is coupled to the rigid segment by elastic hinges. 14. The device of claim 1, wherein the radially outward force is applied by pneumatic, hydraulic, mechanical or electromechanical means. 15. The device of claim 1, wherein the device has a larger diameter in the stable expanded configuration than in the stable contracted configuration. 16. The device of claim 1, wherein one or more of the unit cells have a symmetrical load-displacement characteristic around the transition point. 17. The device of claim 1, wherein one or more of the unit cells have an asymmetrical load-displacement characteristic around the transition point, with the expanded configuration being the more stable configuration. 18. The device of claim 1, wherein one or more of the unit cells have an asymmetrical load-displacement characteristic around the transition point, with the contracted configuration being the more stable configuration. 19. The expandable support device of claim 1, wherein the rigid segment and the flexible segment each have a generally longitudinal wave-like shape, and wherein the rigid segment and the flexible segment are generally in phase when the unit cell is in the stable contracted configuration and generally out of phase when the unit cell is in the stable expanded configuration. 20. The expandable support device of claim 1, wherein the rigid segment and the flexible segment each have an arcuate shape, and at least a first portion of the flexible segment is generally concave when the unit cell is in the stable contracted configuration and at least a portion the flexible segment is generally convex when the unit cell is in the stable expanded configuration. 21. The expandable support device of claim 1, wherein no external influence is required after said unit cell passes the transition point to expand said unit cell from the transition point to the stable expanded configuration. 22. The expandable support device of claim 1, wherein the expandable support device is configured for deployment in a blood vessel. 23. The device of claim 1, wherein the expandable tube is formed at least partially of a biodegradable material. 24. An expandable support device comprising: an expandable tube formed of a plurality of unit cells, at least one unit cell of said plurality of unit cells having a stable contracted configuration and stable expanded configuration, wherein: during a first phase of expansion, said at least one unit cell is expanded beyond a transition point by application of a radially outward force to the expandable tube;during a second phase of expansion that occurs after said unit cell is expanded beyond the transition point, said unit cell automatically expands further toward the stable expanded configuration; andafter the expandable tube is forcibly compressed such that said unit cell is contracted past the transition point, the at least one unit cell is configured to automatically contract further toward the stable contracted configuration. 25. The device of claim 24, wherein the expandable tube comprises a biodegradable material selected from the group consisting of: poly(L-lactide-co-glycolide), polyhydroxyalkanoate, polyester amide, a chitosan and genipin structure and a silicon and iron composite. 26. The device of claim 24, wherein the plurality of unit cells define a wall having a plurality of slots therethrough with at least a portion of the plurality of slots having a wave-like shape when the device is in the stable contracted configuration. 27. The device of claim 24, further comprising a tubular sleeve mounted on the plurality of unit cells. 28. The device of claim 27, wherein the tubular sleeve comprises a drug or bioactive agent. 29. The device of claim 27, wherein no external influence is required after said unit cell passes the transition point to expand said unit cell from the transition point to the stable expanded configuration. 30. The device of claim 24, wherein the expandable tube is formed at least partially of a biodegradable material.
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