A method for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural orifice or lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to wh
A method for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural orifice or lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.
대표청구항▼
1. A prosthetic annulus delivery system comprising: a foldable annuloplasty annular ring configured to have a folded configuration and an un-folded configuration;an expansion assembly comprising an expansion member removably connected to said foldable annular ring when in said folded configuration a
1. A prosthetic annulus delivery system comprising: a foldable annuloplasty annular ring configured to have a folded configuration and an un-folded configuration;an expansion assembly comprising an expansion member removably connected to said foldable annular ring when in said folded configuration and said un-folded configuration, and an actuating catheter connected to said expansion member;an outer catheter coaxially slideably mounted over said expansion assembly between a first position covering said expansion assembly and a second position uncovering said expansion assembly, said catheter having a forward end adapted to receive therein said foldable annular ring and said expansion member when said catheter is arranged in said first position and said annular ring is in said folded configuration, and wherein said expansion assembly is adapted to unfold said annular ring and expel said annular ring from within said forward end of said catheter when said catheter is arranged in said second position uncovering said expansion assembly and said annular ring; anda mechanical tissue interface system, wherein said foldable annular ring is adapted to be secured to tissue adjacent said foldable annular ring when said foldable annular ring is unfolded and wherein said mechanical tissue interface system is configured to respond to an applied force to adhere to the adjacent tissue. 2. The system of claim 1, wherein said annular ring is adapted to fit in a mitral valve opening of a heart. 3. The system of claim 1, wherein said annular ring is adapted to fit in an aortic valve opening of a heart. 4. The system of claim 1, wherein said annular ring is adapted to fit in a pulmonary valve opening of a heart. 5. The system of claim 1, wherein said annular ring is adapted to fit in a tricuspid valve opening of a heart. 6. The system of claim 1, wherein said mechanical tissue interface system comprises retention barbs. 7. The system of claim 1, wherein said expansion member comprises implant support arms that expand to deploy said folded annular ring to a radial dimension. 8. The system of claim 1, wherein said annular ring is radially expandable. 9. The system of claim 1, wherein said annular ring and said mechanical tissue interface system are integrated into a one-piece design. 10. The system of claim 1, wherein said annuloplasty annular ring includes a flexible band. 11. A prosthetic annulus delivery system comprising: a foldable annuloplasty annular ring having a folded configuration and an unfolded configuration;an expansion assembly comprising an expansion member removeably coupled to the annular ring when in both a folded and unfolded configuration, and an actuating catheter connected to said expansion member;an outer catheter coaxially slideably mounted over said expansion assembly between a first position covering said expansion assembly and a second position uncovering said expansion assembly, said catheter having a forward end adapted to receive therein said foldable annular ring and said expansion member when said catheter is arranged in said first position and said annular ring is in said folded configuration, and wherein said expansion assembly is adapted to unfold said annular ring and expel said annular ring from within said forward end of said catheter when said catheter is arranged in said second position uncovering said expansion assembly and said annular ring;a core catheter slideably mounted within the actuating catheter and having a forward end connected to said expansion member; anda mechanical tissue interface system adapted for securing the annular ring in the unfolded configuration to tissue adjacent thereto. 12. A prosthetic annulus delivery system comprising: a foldable annuloplasty annular ring having a folded configuration and an unfolded configuration, the annular ring adapted to be attached to tissue adjacent an anatomical lumen or orifice;an expansion assembly comprising a radial expansion member adapted to be removeably coupled to the annular ring when both in the folded configuration and the unfolded configuration, and an actuating catheter coupled to the expansion member;a longitudinal outer catheter coaxially slideably mounted over the expansion assembly, the catheter having a forward end adapted to capture internally therein the annular ring when in the folded configuration and the expansion member attached to the annular ring when in the folded configuration, wherein the actuating catheter is adapted to unfold the annular ring radially from the folded configuration when the expansion member is exposed by moving the actuating catheter longitudinally relative to the outer catheter and expelling the annular ring from within the catheter; andan adjustment tool adapted to be releasably coupled to the annular ring when in the folded and unfolded configuration for adjusting the size of the annular ring when in the unfolded configuration. 13. The system of claim 12, wherein the expansion member comprises implant support arms that expand to deploy the folded annular ring to a radial dimension. 14. The system of claim 12, further including a core catheter slideably mounted within the actuating catheter and having a forward end connected to said expansion member. 15. The system of claim 1, further including a core catheter slideably mounted within the actuating catheter and having a forward end connected to said expansion member. 16. A prosthetic annulus delivery system for a foldable annuloplasty annular ring, comprising: a foldable annuloplasty annular ring having a folded configuration and an un-folded configuration, the annular ring adapted to be attached to tissue adjacent an anatomical orifice or lumen;a longitudinal catheter having a hollow interior;an expansion assembly coaxially slideably mounted within the interior of the catheter, the expansion assembly removeably coupled to the annular ring when in both the folded configuration and the un-folded configuration,wherein the expansion assembly is moveable relative to the catheter from a first position wherein the expansion assembly and the annular ring in the fold configuration are arranged within the interior of the catheter, and a second position wherein the expansion assembly and the annular ring in the un-folded configuration are arranged outside the interior of the catheter; andan adjustment tool adapted to be releasably coupled to the annular ring for adjusting at least one of the size and shape of the annular ring. 17. The system of claim 16, wherein the expansion assembly includes an expansion member attached to the annular ring, an actuating catheter attached to the expansion member and having a hollow interior, and a core catheter slideable mounted within the interior of the actuating catheter and attached to the expansion member.
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