초록 ▼

A closed loop system or semi-closed loop system for infusing insulin using sensor values applies a redundant sensor system as a fail-safe method against sensor failure. The redundant glucose sensors are used corroborate each other and a failing sensor is detected if the sensors no longer corroborate

A closed loop system or semi-closed loop system for infusing insulin using sensor values applies a redundant sensor system as a fail-safe method against sensor failure. The redundant glucose sensors are used corroborate each other and a failing sensor is detected if the sensors no longer corroborate each other. The use of redundant sensors has the additional benefit of producing better sensor signals compared to the use of a single sensor.

대표청구항 ▼

1. A closed loop system or semi-closed loop system for infusing insulin using sensor values comprising: a first glucose sensor located at a first site generating a first glucose reading;a second glucose sensor located at a second site generating a second glucose reading;a controller configured to pe

1. A closed loop system or semi-closed loop system for infusing insulin using sensor values comprising: a first glucose sensor located at a first site generating a first glucose reading;a second glucose sensor located at a second site generating a second glucose reading;a controller configured to perform the steps of: deriving a first predictive value for the first glucose sensor corresponding to the first glucose reading using the second glucose reading as an input,deriving a second predictive value for the second glucose sensor corresponding to the second glucose reading using the first glucose reading as an input,determining a first error between the first predictive value and the first glucose reading,determining a second error between the second predictive value and the second glucose reading,comparing a sum of the absolute error values of the first and the second errors to a threshold,determining a failing sensor exists if the sum of the absolute error values exceeds the threshold,determining whether the first glucose sensor or the second glucose sensor has the least error in the sensor signal if the sum of the absolute error values does not exceed the threshold,calculating a blood glucose value based on the glucose sensor having the least error in the sensor signal, andreporting the calculated blood glucose value; andan infusion pump delivering insulin based on the reported blood glucose value. 2. The system of claim 1, wherein the controller further performs the steps of: requesting a meter glucose value if the sum of the absolute error values exceeds the threshold; andcomparing the meter glucose value to the first and the second glucose readings to determine if the first or the second glucose sensor is failing. 3. The system of claim 1, wherein the first glucose sensor and the second glucose sensor use different types of technology. 4. The system of claim 1, wherein the first site is subcutaneous tissue, and the second site is blood plasma. 5. The system of claim 1, wherein the first site and the second site are subcutaneous tissue. 6. The system of claim 1, wherein the steps of deriving a first predictive value and deriving a second predictive value use a first and a second adaptive filter. 7. The system of claim 1, wherein the reported blood glucose value is calculated based on the predictive value for the glucose sensor having the least error in the sensor signal. 8. The system of claim 1, wherein the reported blood glucose value is calculated based on the glucose reading generated by the glucose sensor having the least error in the sensor signal. 9. The system of claim 1, wherein the reported blood glucose value is calculated based on the glucose sensor having the least error in the sensor signal and a calibration factor for calibrating the sensor signal from the glucose sensor having the least error in the sensor signal. 10. A closed loop system or semi-closed loop system for infusing insulin using sensor values comprising: a first glucose sensor located at a first site generating a first glucose reading;a second glucose sensor located at a second site generating a second glucose reading;a controller configured to perform the steps of: deriving a first predictive value for the first glucose sensor corresponding to the first glucose reading using the second glucose reading as an input,deriving a second predictive value for the second glucose sensor corresponding to the second glucose reading using the first glucose reading as an input,determining a first error between the first predictive value and the first glucose reading,determining a second error between the second predictive value and the second glucose reading,comparing a sum of the absolute error values of the first and the second errors to a threshold,determining a failing sensor exists if the sum of the absolute error values exceeds the threshold,determining whether the first glucose reading or the second glucose reading is a more reliable glucose reading based on whether the first glucose sensor or the second glucose sensor has the least error in the sensor signal if the sum of the absolute error values does not exceed the threshold, andcalculating a blood glucose value based on the more reliable glucose reading corresponding to the glucose sensor having the least error in the sensor signal; andan infusion pump delivering insulin based on the calculated blood glucose value. 11. The system of claim 10, wherein the controller further performs the step of: reporting the calculated blood glucose value. 12. The system of claim 10, wherein the first glucose sensor and the second glucose sensor corroborate each other. 13. The system of claim 10, wherein the controller further performs the steps of: requesting a meter glucose value if the sum of the absolute error values exceeds the threshold; andcomparing the meter glucose value to the first and the second glucose readings to determine if the first or the second glucose sensor is failing. 14. The system of claim 10, wherein the first glucose sensor and the second glucose sensor use different types of technology. 15. The system of claim 10, wherein the first site is subcutaneous tissue, and the second site is blood plasma. 16. The system of claim 10, wherein the first site and the second site are subcutaneous tissue. 17. The system of claim 10, wherein the steps of deriving a first predictive value and deriving a second predictive value use a first and a second adaptive filter. 18. The system of claim 10, wherein the calculated blood glucose value is calculated based on the predictive value for the glucose sensor having the least error in the sensor signal. 19. The system of claim 10, wherein the calculated blood glucose value is calculated based on the glucose reading generated by the glucose sensor having the least error in the sensor signal. 20. The system of claim 10, wherein the calculated blood glucose value is calculated based on the glucose sensor having the least error in the sensor signal and a calibration factor for calibrating the sensor signal from the glucose sensor having the least error in the sensor signal.