Oxygen-delivery closed cell foam matrix for wound treatment
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61F-013/00
A61F-013/02
A61K-009/70
A61K-009/14
A61L-015/00
A61L-015/16
출원번호
US-0752939
(2000-12-29)
등록번호
US-8679523
(2014-03-25)
발명자
/ 주소
Gibbins, Bruce L.
Hopman, Lance D.
출원인 / 주소
Kimberly-Clark Worldwide, Inc.
대리인 / 주소
Dority & Manning, P.A.
인용정보
피인용 횟수 :
2인용 특허 :
137
초록▼
The present invention comprises methods and compositions for delivery devices. More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide having oxygen and optionally active agents incorpo
The present invention comprises methods and compositions for delivery devices. More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide having oxygen and optionally active agents incorporated therein. The matrix may be formed into any desired shape for treatment of compromised tissue or for delivery of oxygen to a localized environment.
대표청구항▼
1. An oxygen-delivery wound treatment device comprising closed cells and walls, the device comprising: a) a formed biocompatible matrix comprising a swellable, cross-linked polyacrylamide, a non-gellable polysaccharide, and a sodium carbonate catalyst;b) gaseous oxygen, wherein the gaseous oxygen is
1. An oxygen-delivery wound treatment device comprising closed cells and walls, the device comprising: a) a formed biocompatible matrix comprising a swellable, cross-linked polyacrylamide, a non-gellable polysaccharide, and a sodium carbonate catalyst;b) gaseous oxygen, wherein the gaseous oxygen is contained in the closed cells; andc) dissolved oxygen, wherein the dissolved oxygen is present in moisture in the walls, wherein the gaseous oxygen and the dissolved oxygen are produced when hydrogen peroxide is reacted with the sodium carbonate catalyst. 2. The matrix of claim 1, further comprising at least one active agent. 3. The matrix of claim 1, wherein the matrix comprises a stranded configuration. 4. The matrix of claim 1, further comprising a water loss control agent comprising petrolatum, glycolipids, ceramides, free fatty acids, cholesterol, triglycerides, sterylesters, cholesteryl sulfate, linoleic ethyl ester, or silicone oil. 5. The matrix of claim 1, further comprising a plasticizer comprising glycerol, water, propylene glycol, or butanol. 6. The matrix of claim 1, further comprising a hydration control agent comprising isopropyl alcohol, ethanol, glycerol, butanol, or propylene glycol. 7. The matrix of claim 1, wherein the non-gellable polysaccharide is guar gum. 8. An oxygen delivery wound treatment device comprising closed cells and walls, the device comprising; a) a formed biocompatible matrix comprising a swellable, cross-linked polyacrylamide, a non-gellable polysaccharide, and a sodium carbonate catalyst;b) gaseous oxygen, wherein the gaseous oxygen is contained in the closed cells,c) dissolved oxygen, wherein the dissolved oxygen is present in moisture in the walls, wherein the gaseous oxygen and the dissolved oxygen are produced when hydrogen peroxide is reacted with the sodium carbonate catalyst; andd) at least one active agent. 9. The matrix of claim 8, wherein the matrix comprises a stranded configuration. 10. The matrix of claim 8, further comprising a water loss control agent comprising petrolatum, glycolipids, ceramides, free fatty acids, cholesterol, triglycerides, sterylesters, cholesteryl sulfate, linoleic ethyl ester, or silicone oil. 11. The matrix of claim 8, further comprising a plasticizer comprising glycerol, water, propylene glycol, or butanol. 12. The matrix of claim 8, further comprising a hydration control agent comprising isopropyl alcohol, ethanol, glycerol, butanol, or propylene glycol. 13. The matrix of claim 8, wherein the non-gellable polysaccharide is guar gum.
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