초록 ▼

A kit for treatment of acne vulgaris, said formulation of the kit effectively inhibiting or killing Proprionibacterium without antibiotics. A preferred formulation alleviates the four pathogenic factors of acne. In a preferred method using the kit, a first skin-wash formulation comprising a higher z

A kit for treatment of acne vulgaris, said formulation of the kit effectively inhibiting or killing Proprionibacterium without antibiotics. A preferred formulation alleviates the four pathogenic factors of acne. In a preferred method using the kit, a first skin-wash formulation comprising a higher zinc pyrithione concentration than the second leave-on formulation is applied to the affected area and subsequently washed off the skin with water. Then, a second leave-on formulation, preferably comprising a minimum of 0.25% zinc pyrithione with additional ingredients for eliminating or reducing other pathogenic factors of acne vulgaris, is applied to the skin. The kit includes a skin-wash component and a leave-on component comprising the acne treatment of the invention. Formulations are preferably applied as creams, lotions or emulsions.

대표청구항 ▼

1. A kit for treatment of acne, consisting essentially of: a. a first container of about 1.0% to about 2.5% zinc pyrithione; andb. a second container of at least 0.25% zinc pyrithione, therapeutically effective amounts of linoleic acid, and a gallic acid ester selected from the group consisting of p

1. A kit for treatment of acne, consisting essentially of: a. a first container of about 1.0% to about 2.5% zinc pyrithione; andb. a second container of at least 0.25% zinc pyrithione, therapeutically effective amounts of linoleic acid, and a gallic acid ester selected from the group consisting of propyl gallate, n-octyl gallate, n-dodecyl gallate, and combinations thereof. 2. The kit according to claim 1, wherein the contents of said first container are in cream form. 3. The kit according to claim 1, wherein the contents of said second container are in cream form. 4. The kit according to claim 1, wherein the contents of said first container are in lotion form. 5. The kit according to claim 1, wherein the contents of said second container are in lotion form. 6. The kit according to claim 1, wherein the contents of said first container are in emulsion form. 7. The kit according to claim 1, wherein the contents of said second container are in emulsion form. 8. A kit for treatment of acne, consisting essentially of: a. a first container having salicylic acid and about 1.0% to about 2.5% zinc pyrithione; andb. a second container of at least 0.25% zinc pyrithione, therapeutically effective amounts of linoleic acid, and a gallic acid ester selected from the group consisting of propyl gallate, n-octyl gallate, n-dodecyl gallate, and combinations thereof. 9. The kit according to claim 8, wherein the contents of said first container are in cream form. 10. The kit according to claim 8, wherein the contents of said second container are in cream form. 11. The kit according to claim 8, wherein the contents of said first container are in lotion form. 12. The kit according to claim 8, wherein the contents of said second container are in lotion form. 13. The kit according to claim 8, wherein the contents of said first container are in emulsion form. 14. The kit according to claim 8, wherein the contents of said second container are in emulsion form. 15. A kit for treatment of acne, consisting essentially of: a. a first container of about 1.0% to about 2.5% zinc pyrithione; andb. a second container of at least 0.25% zinc pyrithione, therapeutically effective amounts of linoleic acid, and a gallic acid ester selected from the group consisting of propyl gallate, n-octyl gallate, n-dodecyl gallate, and combinations thereof, and therapeutically effective amounts of an additional active ingredient selected from the group consisting of: salicylic acid, retinaldehyde, gamma-linolenic acid, cis 4,7,10,13,16,19-docosahexaenoic acid, cis-6,9,12,15-octatetraenoic acid, arachidonic acid, alpha-linolenic acid, palmitoleic acid, oleic acid, myristoleic acid, zinc salt, pyridoxine hydrochloride, azelaic acid, green tea catechins, flavonoids, isoflavonoids, ethyl laurate, ethyl linoleate, beta-sitosterol, progesterone, spironolactone, Vitamin E, nordihydroguaiaretic acid, dexpanthenol, glycyrrhetinic acid, and combinations thereof. 16. The kit according to claim 15, wherein the contents of said first container are in cream form. 17. The kit according to claim 15, wherein the contents of said second container are in cream form. 18. The kit according to claim 15, wherein the contents of said first container are in lotion form. 19. The kit according to claim 15, wherein the contents of said second container are in lotion form. 20. The kit according to claim 15, wherein the contents of said first container are in emulsion form. 21. The kit according to claim 15, wherein the contents of said second container are in emulsion form.