Automatic baroreflex modulation responsive to adverse event
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61N-001/362
A61N-001/36
출원번호
US-0480063
(2012-05-24)
등록번호
US-8712531
(2014-04-29)
발명자
/ 주소
Kieval, Robert S
Burns, Matthew M
Serdar, David J
출원인 / 주소
CVRx, Inc.
대리인 / 주소
Patterson Thuente Pedersen, P.A.
인용정보
피인용 횟수 :
8인용 특허 :
275
초록▼
A system for providing baroreflex stimulation comprises a sensor to detect a parameter and provide a signal indicative of the parameter and a baroreflex stimulator. The baroreflex stimulator includes a driver to provide a control signal adapted to deliver a baroreflex therapy and a controller to rec
A system for providing baroreflex stimulation comprises a sensor to detect a parameter and provide a signal indicative of the parameter and a baroreflex stimulator. The baroreflex stimulator includes a driver to provide a control signal adapted to deliver a baroreflex therapy and a controller to receive the signal indicative of the parameter and modulate the control signal based on the signal indicative of the parameter to change the baroreflex therapy from a first baroreflex therapy to a second baroreflex therapy.
대표청구항▼
1. A method for operating an implantable medical device, the medical device having a control system contained within an implantable housing, and an electrode coupled to the control system and implanted in contact with a blood vessel, the method comprising: performing a first therapy using the medica
1. A method for operating an implantable medical device, the medical device having a control system contained within an implantable housing, and an electrode coupled to the control system and implanted in contact with a blood vessel, the method comprising: performing a first therapy using the medical device according to a program stored in the control system, including delivering a first baroreflex stimulation signal through the electrode to stimulate a baroreceptor within a wall of the blood vessel, the first therapy programmed to treat a physiological condition through a baroreflex response; andin response to detecting a predetermined threshold value, automatically performing a second therapy using the medical device according to a program stored in the control system, including delivering a second baroreflex stimulation signal through the electrode to stimulate the baroreceptor, the second therapy programmed to treat the physiological condition through a baroreflex response, wherein the second therapy is different from the first therapy. 2. The method of claim 1, wherein performing the first therapy includes withholding therapy and performing the second therapy includes providing baroreflex stimulation. 3. The method of claim 1, wherein performing the first therapy includes providing baroreflex stimulation and performing the second therapy includes withholding therapy. 4. The method of claim 1, wherein the electrode is positioned within a blood vessel. 5. The method of claim 1, wherein the electrode is positioned at least partially surrounding a blood vessel. 6. A method for operating an implantable medical device, the medical device having a control system contained within an implantable housing, and an electrode coupled to the control system and implanted in contact with a blood vessel, the method comprising: performing a first therapy using medical device according to a program stored in the control system, including delivering a first baroreflex stimulation signal through the electrode to stimulate a baroreceptor within a wall of the blood vessel, the first therapy programmed to treat a physiological condition through a baroreflex response; andin response to detecting a predetermined parameter, automatically performing a second therapy using the medical device according to a program stored in the control system, including delivering a second baroreflex stimulation signal through the electrode to stimulate the baroreceptor, the second therapy programmed to treat the physiological condition through a baroreflex response, wherein the second therapy is different from the first therapy. 7. The method of claim 6, wherein the predetermined parameter is selected from the set consisting of: a blood pressure below a lower predetermined threshold, a blood pressure above a higher predetermined threshold, and a specific physiologic event indicative of a need for therapy to treat hypertension and/or heart failure. 8. The method of claim 1, wherein the predetermined threshold value is selected from the group consisting of: blood pressure, heart rate, body movement, activity levels, respiration, and nerve activity. 9. The method of claim 1, wherein each of the first therapy and the second therapy include at least one characteristic selected from the group consisting of: pulse amplitude, pulse frequency, pulse width, pulse duration, pulse waveform, pulse polarity and pulse phase, andwherein the difference between the second therapy and the first therapy comprises a difference in the at least one characteristic. 10. The method of claim 1, wherein the physiological condition is selected from the group consisting of: hypertension, heart failure, cardiovascular disorders, renal disorders, nervous system disorders and low blood pressure. 11. The method of claim 1, wherein the electrode is implanted in contact with a wall of a blood vessel selected from the group consisting of: a carotid sinus, an aortic arch, a common carotid artery, a subclavian artery, a brachiocephalic artery, and a heart. 12. The method of claim 6, wherein the predetermined parameter is selected from the group consisting of: blood pressure, heart rate, body movement, activity levels, respiration, and nerve activity. 13. The method of claim 6, wherein each of the first therapy and the second therapy include at least one characteristic selected from the group consisting of: pulse amplitude, pulse frequency, pulse width, pulse duration, pulse waveform, pulse polarity and pulse phase, andwherein the difference between the second therapy and the first therapy comprises a difference in the at least one characteristic. 14. The method of claim 6, wherein the physiological condition is selected from the group consisting of: hypertension, heart failure, cardiovascular disorders, renal disorders, nervous system disorders and low blood pressure. 15. The method of claim 6, wherein the electrode is implanted in contact with a wall of a blood vessel selected from the group consisting of: a carotid sinus, an aortic arch, a common carotid artery, a subclavian artery, a brachiocephalic artery, and a heart.
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이 특허에 인용된 특허 (275)
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