An ophthalmic dispenser and method of filling and dispensing fluid stored therein. The dispenser includes a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and
An ophthalmic dispenser and method of filling and dispensing fluid stored therein. The dispenser includes a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and a nozzle having a valve defining an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween. The valve interface is connectable in fluid communication with the outlet aperture, and at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to pumped fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The rigid housing is mountable within a cartridge which, in turn, is mountable within a dispenser housing including an eyelid depressor and a trigger for simultaneously actuating the eyelid depressor and pump.
대표청구항▼
1. A method comprising: providing a plurality of cartridges for storing and dispensing an ophthalmic fluid, the plurality of cartridges being substantially identical to one another and each having a vial, a pump, and a nozzle, the vial including an interior fluid receiving chamber defined therein, t
1. A method comprising: providing a plurality of cartridges for storing and dispensing an ophthalmic fluid, the plurality of cartridges being substantially identical to one another and each having a vial, a pump, and a nozzle, the vial including an interior fluid receiving chamber defined therein, the pump being in fluid communication with the fluid receiving chamber for pumping a fluid received therein from the fluid receiving chamber, the nozzle being disposed in fluid communication with the pump for allowing the passage of the pumped fluid therethrough, the cartridge further having a casing that receives the nozzle, the pump, and the vial within, which are arranged in that order along a longitudinal axis moving in a direction toward a posterior end of the cartridge, and the cartridge further having a first actuator operatively coupled to the pump;installing at least one of the plurality of cartridges in an ophthalmic dispenser having a second actuator configured to be operatively coupled to the cartridge, wherein actuation of the second actuator initiates dispensing; andusing at least one of the cartridges to dispense ophthalmic fluid without installing the cartridge in an ophthalmic dispenser having a second actuator configured to be to operatively coupled to the cartridge. 2. A method as defined in claim 1, wherein the first actuator is coupled to the casing. 3. A method as defined in claim 1, wherein the nozzle includes a valve including a valve seat and a flexible valve cover forming an interface therebetween, wherein the interface is in fluid communication with the pump. 4. A method as defined in claim 3, wherein the valve seat and the interface are annular and axially-extending, and the valve further includes an outlet aperture coupled in fluid communication between the valve seat and the pump, wherein the interface is connectable in fluid communication with the outlet aperture. 5. A method as defined in claim 3, wherein at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the interface at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. 6. A method as defined in claim 1, wherein the nozzle includes a valve including an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween, wherein the interface is connectable in fluid communication with the outlet aperture, and at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. 7. A method as defined in claim 1, wherein the pump moves in a direction during pumping that is different than a direction that the first actuator moves during actuation. 8. A method as defined in claim 1, wherein the pump moves in a direction during pumping that is transverse to a direction that the first actuator moves during actuation. 9. A method as defined in claim 1, wherein the pump moves in a direction during pumping that is substantially parallel to the longitudinal axis. 10. A method as defined in claim 1, wherein the casing includes the first actuator. 11. A method as defined in claim 1, wherein upon actuation of the first actuator, either (i) the vial moves relative to the casing to actuate the pump or (ii) one part of the casing moves relative to another part of the casing to actuate the pump. 12. A method comprising: providing a plurality of cartridges for storing and dispensing an ophthalmic fluid, the plurality of cartridges being substantially identical to one another and each having a vial, a pump, and a nozzle, the vial including an interior fluid receiving chamber defined therein, the pump being in fluid communication with the fluid receiving chamber for pumping a fluid received therein from the fluid receiving chamber, the nozzle being disposed in fluid communication with the pump for allowing the passage of the pumped fluid therethrough, the cartridge further having a casing that receives the nozzle, the pump, and the vial within, which are arranged in that order along a longitudinal axis moving in a direction toward a posterior end of the cartridge, and the cartridge further having an actuator operatively coupled to the pump;providing a plurality of dispensers adapted to receive and operate the cartridges, the plurality of cartridges being substantially identical to one another and being capable of operation as a stand alone unit or in the dispenser;selling at least one of the cartridges in combination with at least one of the dispensers; andselling at least one of the cartridges without a dispenser. 13. A method as defined in claim 12, wherein the actuator is coupled to the casing. 14. A method as defined in claim 12, wherein the nozzle includes a valve including a valve seat and a flexible valve cover forming an interface therebetween, wherein the interface is in fluid communication with the pump. 15. A method as defined in claim 14, wherein the valve seat and the interface are annular and axially-extending, and the valve further includes an outlet aperture coupled in fluid communication between the valve seat and the pump, wherein the interface is connectable in fluid communication with the outlet aperture. 16. A method as defined in claim 14, wherein at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the interface at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. 17. A method as defined in claim 2, wherein the nozzle includes a valve including an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween, wherein the interface is connectable in fluid communication with the outlet aperture, and at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. 18. A method as defined in claim 12, wherein the pump moves in a direction during pumping that is different than a direction that the actuator moves during actuation. 19. A method as defined in claim 12, wherein the pump moves in a direction during pumping that is transverse to a direction that the actuator moves during actuation. 20. A method as defined in claim 12, wherein the pump moves in a direction during pumping that is substantially parallel to the longitudinal axis. 21. A method as defined in claim 12, wherein the casing includes the actuator. 22. A method as defined in claim 12, wherein upon actuation of the actuator, either (i) the vial moves relative to the casing to actuate the pump or (ii) one part of the casing moves relative to another part of the casing to actuate the pump. 23. A method for filling an ophthalmic dispenser, the ophthalmic dispenser comprising: a rigid housing defining a first fluid-receiving chamber, and a flange defining a second fluid-receiving chamber axially spaced relative to the first fluid receiving chamber and connectable in fluid communication therewith; a flexible bladder defining an axially-extending body portion receivable within the first fluid-receiving chamber of the housing, a first annular sealing surface, and a second annular sealing surface axially spaced on an opposite side of the first annular sealing surface relative to the axially-extending body portion and receivable within the flange of the housing; a pump coupled in fluid communication with the first fluid-receiving chamber; a nozzle comprising a valve including an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween, wherein the interface is connectable in fluid communication with the outlet aperture, and at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween; and at least one spring drivingly connected to at least one of the pump and housing, wherein the spring moves at least one of the pump and housing relative to the other to actuate the pump, the method comprising the steps of: (i) introducing an ophthalmic fluid into at least the first fluid-receiving chamber of the housing;(ii) inserting the axially-elongated body portion of the flexible bladder at least partially into the first fluid-receiving chamber of the housing such that the first fluid receiving chamber is filled with ophthalmic fluid and at least part of the second fluid-receiving chamber is filled with ophthalmic fluid; and(iii) forming a first substantially fluid-tight seal between the first annular sealing surface of the bladder and the housing, forming a second substantially fluid-tight seal between the second annular sealing surface of the bladder and the flange of the housing such that the first fluid-receiving chamber is filled with ophthalmic fluid substantially without any gas therein, and the second fluid-receiving chamber is at least partially filled with ophthalmic fluid. 24. A method as defined in claim 23, further comprising the step of collapsing the flexible bladder prior to inserting the bladder into the first fluid-receiving chamber of the housing.
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