Polymer composites for biomedical applications and methods of making
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-018/00
A61B-018/12
A61B-018/20
출원번호
US-0797453
(2010-06-09)
등록번호
US-8771265
(2014-07-08)
발명자
/ 주소
Truckai, Csaba
출원인 / 주소
DFINE, Inc.
대리인 / 주소
Vista IP Law Group LLP
인용정보
피인용 횟수 :
0인용 특허 :
15
초록▼
A biomedical polymer composite that exhibits ultra-low thermal conductivity properties. In a preferred embodiment, the biomedical polymer composite comprises a base polymer component with a dispersed thermally non-conductive filler component consisting of glass or ceramic nanospheres or microspheres
A biomedical polymer composite that exhibits ultra-low thermal conductivity properties. In a preferred embodiment, the biomedical polymer composite comprises a base polymer component with a dispersed thermally non-conductive filler component consisting of glass or ceramic nanospheres or microspheres that have a thermal conductivity of less than 5 W/m-K, and preferably less than 2 W/m-K. In one embodiment, the polymer composite has an electrically conductive filler and can be used in a filament for treating arteriovascular malformations. In another embodiment, the polymeric composite can be used as an energy-coupling means to apply energy to tissue.
대표청구항▼
1. A method of thermally treating tissue in a body, comprising: selecting a targeted portion of a tissue structure to be ablated using transmitted energy;identifying a nearby insulation portion of tissue to be insulated from the transmitted energy;introducing a flowable material into a delivery lume
1. A method of thermally treating tissue in a body, comprising: selecting a targeted portion of a tissue structure to be ablated using transmitted energy;identifying a nearby insulation portion of tissue to be insulated from the transmitted energy;introducing a flowable material into a delivery lumen of an elongate introducer, such that the flowable material flows through the delivery lumen, exits out a distal opening of the elongate introducer, and is deposited onto the insulation portion of tissue, thereby forming an insulative layer on the insulation portion of tissue;electrically coupling a radiofrequency (RF) energy source to a conductive liquid or gel electrode contacting the targeted portion of the tissue structure;transmitting RF energy from the RF energy source to the targeted portion of the tissue structure via the conductive liquid or gel electrode to thereby treat at least a portion of the targeted portion of the tissue structure. 2. The method of claim 1, wherein introducing the flowable material comprises extruding the flowable material through the delivery lumen. 3. The method of claim 2, wherein extruding comprises manually actuating an extrusion device configured to induce flow of the flowable material out the distal opening of the elongate introducer. 4. The method of claim 1, wherein the insulative layer comprises a base polymer and a dispersed nonconductive filler. 5. The method of claim 4, wherein the nonconductive filler comprises hollow microspheres. 6. The method of claim 4, wherein the base polymer comprises a bio-absorbable material. 7. The method of claim 5, wherein the hollow microspheres comprise a ceramic or glass. 8. The method of claim 4, wherein the base polymer is selected from the group consisting of: polyamide, polycarbonate, polystyrene, polyacrylonitrile, polyacetal, thermoplastic modified cellulose, polysulfone, thermoplastic polyester, PET, poly(ethyl acrylate), poly(methyl methacrylate), nylon, fluoropolymer, polyvinylidene fluoride, and ethylene tetrafluoroethylene. 9. The method of claim 1, wherein the insulative layer has a thermal conductivity of less than about 5 W/m-K. 10. The method of claim 1, wherein the insulative layer comprises a thermochromic material.
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