Artificial bone and joint compositions and methods of use and manufacture
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
C04B-035/057
C04B-035/44
A61F-002/28
A61F-002/30
출원번호
US-0852795
(2010-08-09)
등록번호
US-8778822
(2014-07-15)
발명자
/ 주소
McGowan, Kenneth A.
출원인 / 주소
Cabertech, Inc.
대리인 / 주소
Buchanan Ingersoll & Rooney PC
인용정보
피인용 횟수 :
0인용 특허 :
21
초록▼
The present invention provides a ceramic porous body for in-vitro and in-vivo use comprising a composition comprising a calcium aluminate (CA) containing phase and optionally at least one of an accelerator, a retarder, a surfactant, a foaming agent, a reactive alumina, water, a fiber, and a biologic
The present invention provides a ceramic porous body for in-vitro and in-vivo use comprising a composition comprising a calcium aluminate (CA) containing phase and optionally at least one of an accelerator, a retarder, a surfactant, a foaming agent, a reactive alumina, water, a fiber, and a biologically active material, and combinations thereof. Ceramic compositions are provides as well as method of using the ceramic compositions and methods of manufacturing a ceramic porous body. The ceramic porous bodies of this invention may be used as artificial bones, joints, in-vitro support structures, and in-vivo support structures for cells, tissues, organs, and nerve growth and regeneration.
대표청구항▼
1. A porous ceramic composition consisting essentially of: a calcium aluminate (CA) containing phase having the formula CnAy, wherein n is an integer from about 1 to about 12 and y is an integer from about 1 to about 24, said CA containing phase having at least a CaAl2O4 phase and a CaAl4O7 phase, i
1. A porous ceramic composition consisting essentially of: a calcium aluminate (CA) containing phase having the formula CnAy, wherein n is an integer from about 1 to about 12 and y is an integer from about 1 to about 24, said CA containing phase having at least a CaAl2O4 phase and a CaAl4O7 phase, including phosphate containing phases resulting from the interaction of CnAy, CnAy-hydrates wherein n is an integer from about 1 to about 12 and y is an integer from about 1 to about 24, CaO, AlnOy, and AlnOy-hydrates wherein n is an integer from about 1 to about 12 and y is an integer from about 1 to about 24 with PnOyx, wherein in the formula PnOy n is an integer 1, 2, or 3 and y is an integer 3, 4, or 7 and x is a negatively charged integer of 1, 3, or 4; anda biologically active material that comprises one or more proteins for promoting bone growth. 2. The porous ceramic composition of claim 1 further including interconnected porosity. 3. The porous ceramic composition of claim 1 that supports stem cells. 4. The porous ceramic composition of claim 3 wherein said stem cells differentiate into osteoblasts. 5. The ceramic porous composition of claim 1 that is rehydrated in-vivo. 6. The porous ceramic composition of claim 1 further including wherein said phosphate is a raw material for osteoblast precipitation of natural bone. 7. The porous ceramic composition of claim 6 wherein said phosphate is calcium orthophosphate.
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이 특허에 인용된 특허 (21)
McGowan, Kenneth A., Artificial bone and joint compositions and methods of use and manufacture.
Axen,Niklas; Bjorklund,Kajsa; Hermansson,Leif; Engqvist,Hakan, Method of making structured ceramic coatings and coated devices prepared with the method.
Bajpai Praphulla K. (Dayton OH) Graves George A. (Dayton OH), Porous ceramic carriers for controlled release of proteins, polypeptide hormones, and other substances within human and/.
Hermansson,Leif; Kraft,Lars; Engqvist,H{dot over (a)}kan; Hermansson,Irmeli; Ahnfelt,Nils Otto; Gomez Ortega,Gunilla, Powdered material and ceramic material manufactured therefrom.
Wieland Klaus (Wiesbaden DEX) Weichert Thomas (Hohenstein DEX) Eschner Axel (Wiesbaden DEX) Whrmeyer Christoph (Wiesbaden DEX), Refractory or fireproof brick as tin bath bottom brick.
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