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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0473355 (2012-05-16) |
등록번호 | US-8784400 (2014-07-22) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 20 인용 특허 : 521 |
Devices and methods for delivering substances to lung tissue through an extra-anatomic passage created in an airway.
1. A method of accessing lung tissue through an opening in an airway wall, the method comprising: advancing a catheter into the lung;advancing the catheter through the opening in the airway wall to access a treatment site in lung tissue beyond the airway wall;accessing the treatment site using the c
1. A method of accessing lung tissue through an opening in an airway wall, the method comprising: advancing a catheter into the lung;advancing the catheter through the opening in the airway wall to access a treatment site in lung tissue beyond the airway wall;accessing the treatment site using the catheter; andperforming a procedure at the treatment site. 2. The method of claim 1, wherein accessing the treatment site using the catheter and performing a procedure at the treatment site comprises delivering a substance through the opening to treat a region of diseased tissue beyond the airway wall in the lung. 3. The method of claim 2, wherein the step of delivering the substance through the opening comprises delivering the substance through the opening to treat a tumor. 4. The method of claim 2, wherein the substance comprises a substance selected from the group consisting of antimetabolites, antithrobotics, anticoagulants, antiplatelet agents, thorombolytics, antiproliferatives, anti-inflammatories, agents that inhibit hyperplasia, agents that inhibit restenosis, anti-angiogenic agents or angiogenesis inhibitors, smooth muscle cell inhibitors, growth factors, growth factor inhibitors, cell adhesion inhibitors, cell adhesion promoters and a combination thereof. 5. The method of claim 1, further comprising preventing closure of the opening wherein said preventing step is performed using a mechanical means. 6. The method of claim 5, wherein said mechanical means comprises an act selected from the group consisting of a) inserting an implant within and b) dilating the opening. 7. The method of claim 1, further comprising creating the opening. 8. The method of claim 1 wherein the catheter comprises a rounded distal end. 9. A method of accessing lung tissue through an opening in an airway wall, the method comprising: advancing a catheter into the lung;advancing a rounded end of the catheter through the opening in the airway wall to access a treatment site in lung tissue beyond the airway wall;accessing the treatment site using the catheter; andperforming a procedure at the treatment site. 10. The method of claim 9, wherein performing a procedure at the treatment site using the catheter comprises delivering a substance through the opening to treat a region of diseased tissue beyond the airway wall in the lung. 11. The method of claim 10, wherein the step of delivering the substance through the opening comprises delivering the substance through the opening to treat a tumor. 12. The method of claim 10, further comprising creating the opening. 13. The method of claim 9, further comprising preventing closure of the opening wherein said preventing step is performed using a mechanical means. 14. The method of claim 13, wherein said mechanical means comprises an act selected from the group consisting of a) inserting an implant within and b) dilating the opening. 15. A method of accessing lung tissue through an opening in an airway wall, the method comprising: advancing a catheter into the lung;enlarging the opening;advancing a rounded end of the catheter into the opening in the airway wall to access a treatment site in lung tissue beyond the airway wall;preventing closure of the opening;accessing the treatment site using the catheter; andperforming a procedure at the treatment site. 16. The method of claim 15, wherein performing a procedure at the treatment site using the catheter comprises delivering a substance through the opening to treat a region of diseased tissue beyond the airway wall in the lung. 17. The method of claim 15, further comprising delivering electrical energy with the catheter. 18. The method of claim 15, wherein preventing closure of the opening is performed using a mechanical means. 19. The method of claim 18, wherein said mechanical means comprises an act selected from the group consisting of a) inserting an implant in the opening, b) dilating the opening, and c) temporarily holding open the opening with an instrument. 20. The method of claim 15, wherein a piercing member is withdrawn from the opening prior to advancing the rounded end of the catheter.
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