Method of reshaping a heart valve annulus using an intravascular device
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61F-002/24
A61B-017/00
출원번호
US-0846850
(2004-05-14)
등록번호
US-8784482
(2014-07-22)
발명자
/ 주소
Rahdert, David A.
Machold, Timothy R.
Macoviak, John A.
Chang, Robert T.
출원인 / 주소
MVRx, Inc.
대리인 / 주소
Ryan Kromholz & Manion, S.C.
인용정보
피인용 횟수 :
37인용 특허 :
47
초록▼
Devices, systems, and methods employ an implant that is sized and configured to attach in, on, or near the annulus of a dysfunctional heart valve. In use, the implant extends either across the minor axis of the annulus, or across the major axis of the annulus, or both. The implant restores to the he
Devices, systems, and methods employ an implant that is sized and configured to attach in, on, or near the annulus of a dysfunctional heart valve. In use, the implant extends either across the minor axis of the annulus, or across the major axis of the annulus, or both. The implant restores to the heart valve annulus and leaflets a more functional anatomic shape and tension. The more functional anatomic shape and tension are conducive to coaptation of the leaflets, which, in turn, reduces retrograde flow or regurgitation.
대표청구항▼
1. A method comprising identifying for treatment a heart having a right atrium and a left atrium separated by an interatrial septum, the left atrium including a mitral valve having an annulus with a minor axis with a native length extending along an annular plane in a posterior-to-anterior direction
1. A method comprising identifying for treatment a heart having a right atrium and a left atrium separated by an interatrial septum, the left atrium including a mitral valve having an annulus with a minor axis with a native length extending along an annular plane in a posterior-to-anterior direction within the left atrium,providing an implant comprising a rail portion, a posterior portion joined to the rail portion, and an anterior portion joined to the rail portion,deploying the implant through an intravascular path from the right atrium through the interatrial septum into the left atrium including positioning the anterior portion of the implant entirely inside the heart and solely within the right atrium in contact solely with the interarterial septum above an anterior region of the annulus,positioning the posterior portion of the implant entirely inside the heart and solely within the left atrium in contact solely with tissue above a posterior region of the annulus, andpositioning the rail portion of the implant entirely inside the heart and solely within the left atrium in a path that spans across the minor axis of the annulus between the posterior region above the annulus and the interarterial septum above the anterior region of the annulus, andshortening the native length of the minor axis of the annulus including anchoring the posterior portion of the implant solely to tissue inside the heart in a wall of the left atrium above the posterior region of the annulus, andpulling on the anterior portion of the implant from within the right atrium to place the rail portion in tension within the left atrium, whereby the pulling exerts a pulling force on tissue within the left atrium at or near the posterior region of the annulus to draw the posterior region of the annulus inwardly toward the anterior region of the annulus without exerting a pulling force on the anterior region of the annulus, to thereby shorten the annulus along the minor axis, andanchoring the anterior portion of the implant solely to tissue in the interatrial septum solely within the right atrium above the anterior region of the annulus to hold the tension on the rail portion. 2. A method according to claim 1, wherein the rail portion comprises a wire-form structure. 3. A method according to claim 1, wherein the rail portion comprises an elastic material. 4. A method according to claim 1, wherein the deploying the implant includes collapsing the implant for placement within a catheter. 5. A method according to claim 1, wherein anchoring the anterior portion includes coupling a tissue-engaging fixation element on the anterior portion solely within the right atrium above the anterior region of the annulus.
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