[특허]Frozen compositions and methods for piercing a substrate

The Invention Science Fund I, LLC

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Frozen compositions and methods for piercing a substrate

특허상세정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	G06F-019/00 A61M-037/00 A61K-009/00 A61K-031/7088 A61K-009/16 A61K-009/24 A61K-038/38 A61K-009/14 A61K-038/48 A61K-031/70 A61K-033/00 A61K-031/337 A61K-039/145 A61K-031/00 A61K-045/06 C07K-016/28 A61K-031/74 A61K-009/08 C07K-016/30 A61K-009/19 A61K-009/20 A61K-041/00 C07K-016/22 A61K-009/28 A61K-009/12 A61K-039/00
미국특허분류(USC)	702/019; 604/173
출원번호	US-0586071 (2009-09-15)
등록번호	US-8798932 (2014-08-05)
발명자 / 주소	Boyden, Edward S. Cook, Daniel B. Hyde, Roderick A. Leuthardt, Eric C. Myhrvold, Nathan P. Sweeney, Elizabeth A. Wood, Jr., Lowell L.
출원인 / 주소	The Invention Science Fund I, LLC
인용정보	피인용 횟수 : 2 인용 특허 : 133

초록

Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

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1. A system comprising: at least one computing device;one or more instructions that when executed on the at least one computing device cause the at least one computing device to receive a first input associated with a first possible dataset,the first possible dataset including data representative of at least one parameter for making or administering at least one frozen ice piercing implement, wherein the frozen ice piercing implement consists essentially of frozen ice and contains at least one detection material; andone or more instructions that when executed generate an output to a user readable display. 2. The system of claim 1, further including one or more instructions that when executed on the at least one computing device cause the at least one computing device to compare a value associated with the first possible dataset with a second dataset including values of at least one predictive parameter for making the at least one frozen ice piercing implement. 3. The system of claim 2, further including one or more instructions that when executed on the at least one computing device cause the at least one computing device to determine a graphical illustration of the second possible dataset. 4. The system of claim 1, wherein the at least one parameter for making the at least one frozen ice piercing implement includes one or more of: constitution of the at least one frozen ice piercing implement, formulation of the at least one frozen ice piercing implement, size of the at least one frozen ice piercing implement, density of the at least one frozen ice piercing implement, shape of the at least one frozen ice piercing implement, physical structure of the at least one frozen ice piercing implement, or physical or chemical integrity of the at least one frozen ice piercing implement. 5. The system of claim 1, wherein the at least one parameter for administering the at least one frozen ice piercing implement includes one or more of: substrate type; substrate function; substrate size; substrate constitution; substrate architecture; substrate durability; substrate temperature; temperature of administration conditions; depth of administration of the at least one frozen ice particle composition or frozen ice piercing implement; substrate source; one or more temporal coordinates; one or more spatial coordinates; presence or absence of at least one agent; presence or absence of at least one microparticle, nanoparticle, lens, tunable lens, sensor, transducer, actuator, detector, heater, valve, gate, channel, detection material, pump, power source, injector, controller, receiver, transmitter, or circuit; angle of administration of the at least one frozen ice piercing implement; force of administration of the at least one frozen ice piercing implement, velocity of administration of the at least one frozen ice piercing implement; quantity of frozen ice piercing implement devices administered; rate of administration of more than one frozen ice piercing implements; method of administration of at least one frozen ice piercing implement; timing of administration of at least one frozen ice piercing implement; or rate of delivery of at least one agent of the frozen piercing implement. 6. The system of claim 2, further including one or more instructions that when executed on the at least one computing device cause the at least one computing device to determine from the comparison at least one parameter for making or administering at least one frozen ice piercing implement to at least one substrate. 7. The system of claim 1, further including one or more instructions that when executed on the at least one computing device cause the at least one computing device to access the first possible dataset in response to the first input. 8. The system of claim 1, further including one or more instructions that when executed on the at least one computing device cause the at least one computing device to generate the first possible dataset in response to the first input. 9. The system of claim 1, further including one or more instructions that when executed on the at least one computing device cause the at least one computing device to determine a graphical illustration of the first possible dataset. 10. The system of claim 1, wherein the at least one computing device includes one or more of a desktop computer, workstation computer, or computing system. 11. The system of claim 1, wherein the at least one computing device includes one or more of a cluster of processors, a networked computer, a tablet personal computer, a laptop computer, a mobile device, a mobile telephone, or a personal digital assistant computer. 12. The system of claim 1, wherein the output includes one or more instructions for making the at least one frozen ice piercing implement. 13. The system of claim 1, wherein the output includes at least one graphical description of the at least one frozen ice piercing implement. 14. The system of claim 1, wherein the user readable display is readable by at least one person, or computer. 15. The system of claim 1, wherein the user readable display includes one or more of a display of one or more differences identified by the comparison of at least one value related to the first input and at least one value related to at least one property of the at least one frozen ice piercing implement. 16. The system of claim 1, wherein the user readable display includes one or more of a display of one or more differences identified by the comparison of at least one value related to a second input and at least one value related to at least one parameter for administration of the at least one frozen ice piercing implement. 17. A system comprising: circuitry for accepting a first input associated with one or more parameters for making at least one frozen ice piercing implement, wherein the at least one frozen ice piercing implement consists essentially of frozen ice and includes a detection material;circuitry for accepting a second input associated with one or more parameters for administering at least one frozen ice piercing implement to at least one substrate;circuitry for processing the first input and the second input; andcircuitry for generating an output to a user readable display. 18. The system of claim 17, wherein the one or more parameters for making at least one frozen ice piercing implement include at least one value derived from an image. 19. The system of claim 17, further including circuitry for displaying results of the processing. 20. The system of claim 17, further including circuitry for transmitting one or more signals that include information related to the processing the first input and the second input. 21. The system of claim 17, wherein the output includes one or more instructions for making the at least one frozen ice piercing implement. 22. The system of claim 17, wherein the output includes at least one graphical description of the at least one frozen ice piercing implement. 23. The system of claim 17, wherein the user readable display is readable by at least one person, or computer. 24. The system of claim 17, wherein the user readable display includes one or more of a display of one or more differences identified by the comparison of at least one value related to the first input and at least one value related to at least one property of the at least one frozen ice piercing implement. 25. The system of claim 17, wherein the user readable display includes one or more of a display of one or more differences identified by the comparison of at least one value related to the second input and at least one value related to at least one parameter for administration of the at least one frozen ice piercing implement. 26. A system comprising: circuitry for accepting a first input associated with at least one parameter for making at least one frozen ice piercing implement device, wherein the at least one frozen ice piercing implement consists essentially of frozen ice and includes a detection material;circuitry for accepting a second input associated with at least one parameter for administering at least one frozen ice piercing implement device to at least one substrate;circuitry for processing the first input and the second input; andcircuitry for generating an output to a user readable display. 27. The system of claim 26, wherein the at least one frozen ice piercing implement device includes at least one frozen ice piercing implement array device, frozen ice piercing implement fluidic device, or frozen ice piercing implement injection device. 28. The system of claim 26, wherein the first input includes at least one value derived from at least one image. 29. The system of claim 26, wherein the at least one characteristic of the one or more frozen ice piercing implement device includes one or more of number of frozen ice piercing implements, number of total piercing implements, size of at least one frozen ice piercing implement, constitution of at least one frozen ice piercing implement, shape of at least one frozen ice piercing implement, shape of the device, configuration of the device, spacing of at least two components of the device, spacing of at least two frozen ice piercing implements of the device, or presence or absence of at least one microparticle, nanoparticle, lens, tunable lens, sensor, transducer, actuator, detector, heater, valve, gate, channel, detection material, pump, power source, injector, controller, receiver, transmitter, or circuit. 30. The system of claim 26, wherein the first input includes at least one parameter for making the at least one frozen ice piercing implement device includes one or more of: constitution of the at least one frozen ice piercing implement of the frozen ice piercing implement device, constitution of the at least one frozen ice piercing implement device, configuration of the at least one frozen ice piercing implement or frozen ice piercing implement device, formulation of the at least one frozen ice piercing implement of the frozen ice piercing implement device, formulation of the at least one frozen ice piercing implement device, size of the at least one frozen ice piercing implement of the frozen ice piercing implement device, size of the at least one frozen ice piercing implement device, shape of the at least one frozen ice piercing implement of the frozen ice piercing implement device, shape of the at least one frozen ice piercing implement device, physical structure of the at least one frozen ice piercing implement of the frozen ice piercing implement device, physical structure of the at least one frozen ice piercing implement device, physical or chemical integrity of the at least one frozen ice piercing implement of the frozen ice piercing implement device, physical or chemical integrity of the at least one frozen ice piercing implement device, or presence or absence of at least one microparticle, nanoparticle, lens, tunable lens, sensor, transducer, actuator, detector, heater, valve, gate, channel, detection material, pump, power source, injector, controller, receiver, transmitter, or circuit, in the at least one frozen ice piercing implement or frozen ice piercing implement device. 31. The system of claim 26, wherein the second input includes at least one parameter for administering the at least one frozen ice piercing implement device includes one or more of: substrate type; substrate function; substrate size; substrate constitution; substrate architecture; substrate durability; substrate temperature; temperature of administration conditions; depth of administration of the at least one frozen ice particle composition or frozen ice piercing implement; substrate source; one or more temporal coordinates; one or more spatial coordinates; presence or absence of at least one agent; presence or absence of at least one microparticle, nanoparticle, lens, tunable lens, sensor, transducer, actuator, detector, heater, valve, gate, channel, detection material, pump, power source, injector, controller, receiver, transmitter, or circuit; angle of administration of the at least one frozen ice piercing implement device; force of administration of the at least one frozen ice piercing implement device; velocity of administration of the at least one frozen ice piercing implement device; quantity of frozen ice piercing implements of the device; quantity of frozen ice piercing implement devices administered; rate of administration of more than one frozen ice piercing implement devices; method of administration of at least one frozen ice piercing implement device; timing of administration of at least one frozen ice piercing implement; or rate of delivery of at least one agent of the device. 32. The system of claim 31, wherein the at least one agent includes at least one therapeutic agent, abrasive, explosive material, adhesive agent, or biological remodeling agent. 33. The system of claim 26, further including circuitry for transmitting one or more signals that include information related to the processing the first input and the second input. 34. The system of claim 26, wherein the output includes one or more instructions for making the at least one frozen ice piercing implement device. 35. The system of claim 26, wherein the output includes at least one graphical description of the at least one frozen ice piercing implement device. 36. The system of claim 26, wherein the user includes at least one entity. 37. The system of claim 36, wherein the entity includes at least one person, or computer. 38. The system of claim 26, wherein the user readable display includes one or more of a display of one or more differences identified by the comparison of at least one value related to the first input and at least one value related to at least one property of the at least one frozen ice piercing implement device. 39. The system of claim 26, wherein the user readable display includes one or more of a display of one or more differences identified by the comparison of at least one value related to the second input and at least one value related to at least one parameter for administration of the at least one frozen ice piercing implement device. 40. A system comprising: at least one computing device;circuitry for selecting a combination of at least two parameters related to the content of one or more frozen ice therapeutic piercing implements, wherein the one or more frozen ice therapeutic piercing implements consist essentially of frozen ice and include a detection material,wherein the content of one or more frozen ice therapeutic piercing implements further includes at least one of a therapeutic agent including one or more of an analgesic, anesthetic, antibiotic, anti-inflammatory agent, anti-coagulant, or chemotherapeutic agent; andcircuitry for generating an output indicating the combination to a user readable display. 41. The system of claim 40, wherein the detection material includes at least one colorimetric material or electronic identification device. 42. A system comprising: at least one computing device;one or more instructions that when executed on the at least one computing device cause the at least one computing device to receive a first input associated with a first possible dataset,the first possible dataset including data representative of at least one parameter for making or administering at least one frozen ice piercing implement, wherein the frozen ice piercing implement consists essentially of frozen ice and contains at least one therapeutic agent, at least one adhesive agent, or at least one biological remodeling agent; andone or more instructions that when executed generate an output to a user readable display. 43. A system comprising: at least one computing device;circuitry for selecting a combination of at least two parameters related to the content of one or more frozen ice therapeutic piercing implements, wherein the one or more frozen ice therapeutic piercing implements consist essentially of frozen ice and include at least one therapeutic agent, at least one adhesive agent, or at least one biological remodeling agent,wherein the therapeutic agent includes one or more of an analgesic, anesthetic, antibiotic, anti-inflammatory agent, anti-coagulant, or chemotherapeutic agent; andcircuitry for generating an output indicating the combination to a user readable display.

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Frozen compositions and methods for piercing a substrate

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