초록 ▼

The present invention provides a dissolvable medical sealing device (3, 4; 6, 7; 9) for closing a wound in vessel. A sealing device (3, 4, 6, 7, 9) according to the invention is made of a material that dissolves by means of physical processes, rather than by means of chemical or biological processes

The present invention provides a dissolvable medical sealing device (3, 4; 6, 7; 9) for closing a wound in vessel. A sealing device (3, 4, 6, 7, 9) according to the invention is made of a material that dissolves by means of physical processes, rather than by means of chemical or biological processes. Such a sealing device (3, 4; 6, 7; 9) can be made of polyethylene glycol, polypropylene glycol, copolymers containing ethylene glycol and propylene glycol, polyvinyl alcohol or polyvinyl pyrolidone, or any combinations thereof.

대표청구항 ▼

1. An implantable wound closure device for closing a wound in a vessel, comprising: a first sealing device configured to be positioned against an inner surface of a wall of the vessel, anda fastener fastened to the first sealing device, wherein the fastener is configured to pass through the wound an

1. An implantable wound closure device for closing a wound in a vessel, comprising: a first sealing device configured to be positioned against an inner surface of a wall of the vessel, anda fastener fastened to the first sealing device, wherein the fastener is configured to pass through the wound and to keep the first sealing device in place,wherein the first sealing device is made of a polymer material,wherein the first sealing device is configured to dissolve by erosion caused by physical processes occurring within the vessel without chemical or biological degradation,wherein, upon implantation, the first sealing device is configured to dissolve by erosion caused by the physical processes occurring within the vessel at at least one exposed surface of the first sealing device that is exposed to an interior of the vessel, andwherein the first sealing device consists of one or more of the following: polypropylene glycol, polyacrylic acid, polyvinyl methyl ether-maleic anhydride, xanthan gum, guar gum, and pectin. 2. An implantable wound closure device according to claim 1, further comprising a second sealing device made of a polymer material, adapted to be positioned against an outer surface of the wall of the vessel, and configured to dissolve by physical processes without substantial chemical or biological degradation. 3. An implantable wound closure device according to claim 1, wherein the first sealing device is configured to dissolve in water by erosion caused by physical processes without substantial chemical or biological degradation. 4. An implantable wound closure device according to claim 1, wherein the first sealing device is configured to start dissolving essentially immediately after positioning of the first sealing device within the vessel. 5. An implantable wound closure device according to claim 1, wherein the first sealing device is configured to dissolve in seven days or less after the implantation. 6. An implantable wound closure device according to claim 1, wherein the first sealing device is configured to dissolve in three days or less after the implantation. 7. An implantable wound closure device according to claim 1, wherein the first sealing device is configured to dissolve in 24 hours after the implantation. 8. An implantable wound closure device according to claim 1, wherein the first sealing device is water-soluble. 9. An implantable wound closure device according to claim 1, wherein the first sealing device comprises polypropylene glycol. 10. An implantable wound closure device according to claim 1, wherein the first sealing device is configured to erode due to blood flow wear on the first sealing device. 11. An implantable wound closure device according to claim 1, wherein the first sealing device is configured to dissolve inside the vessel after three days and before seven days. 12. An implantable wound closure device according to claim 1, wherein the first sealing device is configured to dissolve inside the vessel in less than seven days. 13. An implantable wound closure device according to claim 1, wherein the first sealing device and the fastener are made from different materials. 14. An implantable wound closure device according to claim 1, wherein the fastener is configured to dissolve later than the first sealing device after the first sealing device is implanted in the vessel. 15. An implantable wound closure device for closing a wound in a vessel, comprising: a first sealing device configured to be positioned against an inner surface of a wall of the vessel, anda fastener fastened to the first sealing device, wherein the fastener is configured to pass through the wound and to keep the first sealing device in place,wherein the first sealing device is made of a polymer material,wherein the first sealing device is configured to dissolve by erosion caused by physical processes occurring within the vessel without chemical or biological degradation,wherein, upon implantation, the first sealing device is configured to dissolve by erosion caused by the physical processes occurring within the vessel at at least one exposed surface of the first sealing device that is exposed to an interior of the vessel, andwherein the first sealing device comprises at least 90% by weight of one or more of the following: polypropylene glycol, polyacrylic acid, polyvinyl methyl ether-maleic anhydride, xanthan gum, guar gum, and pectin. 16. An implantable wound closure device according to claim 15, further comprising a second sealing device made from a polymer material, adapted to be positioned against an outer surface of the wall of the vessel, and configured to dissolve by physical processes without substantial chemical or biological degradation. 17. An implantable wound closure device according to claim 15, wherein the first sealing device is configured to dissolve in water by erosion caused by physical processes without substantial chemical or biological degradation. 18. An implantable wound closure device according to claim 15, wherein the first sealing device is configured to start dissolving essentially immediately after positioning of the first sealing device within the vessel. 19. An implantable wound closure device according to claim 15, wherein the first sealing device is configured to dissolve in three days or less after the implantation. 20. An implantable wound closure device according to claim 15, wherein the first sealing device is configured to erode due to blood flow wear on the first sealing device. 21. An implantable wound closure device according to claim 15, wherein the first sealing device is configured to dissolve inside the vessel after three days and before seven days. 22. An implantable wound closure device according to claim 15, wherein the first sealing device is configured to dissolve inside the vessel in less than seven days.